日本耳鼻咽喉科学会会報
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
82 巻, 8 号
選択された号の論文の8件中1~8を表示しています
  • 杉田 麟也, 市川 銀一郎, 後藤 重雄, 柏木 譲治
    1979 年 82 巻 8 号 p. 751-757
    発行日: 1979/08/20
    公開日: 2008/03/19
    ジャーナル フリー
    Bacteriological investigation of the middle ear and nasopharynx in 132 patients with fresh acute purulent otitis media was performed. Results are as follows:
    1. Complete bacterial coincidence was noted in 80% of 132 cases, partial coincidence in 12%, and no coincidence in 8%. Considerable coincidence of bacteria in the middle ear and nasopharynx occurred in 92% of 132 cases.
    2. Staphylococcus aureus could not be expected as a pathogen in most of these cases. From the results of present investigation, it is concluded that the pathogens of acute otitis media may be suspected from the bacterial culture of the nasopharynx. A82-0751-22162
  • 酒井 昇, 寺土 吉彦
    1979 年 82 巻 8 号 p. 758-763
    発行日: 1979/08/20
    公開日: 2008/03/19
    ジャーナル フリー
    Desmoid tumor is a benign fibrous neoplasma which arises from musculoaponeurotic structures throughout the body and is classified between benign and malignant tumors. This tumor was first described by Macfarlane in 1832 as a abdominal wall tumor and usually it was seen in the abdominal wall of multiparous woman. But since then, desmoid tumors which arose from elsewhere other than the abdominal wall have been reported, so that they were classified into two types; abdominal desmoid and extra-abdominal desmoid tumors. Both types have been reported in many cases until now. Among extra-abdominal desmoid tumors, the cases seen in the face and head were so rare that we could find only about 20 cases in the world literature. Recently we experienced a case of desmoid tumor in the facial region. The patient was a 28-year-old male whose chief complaint was the swelling of the lateral surface of the external nose on both sides. It was surgically removed and pathologically proved as desmoid tumor. Desmoid tumor of the external nose has been reported only in one case by Masson so far, and because of its rarity, we reported one case with a review of the literature.
  • 主として小脳性眼運動異常
    亀井 民雄, 金子 裕, 石井 英男, 森川 昭広
    1979 年 82 巻 8 号 p. 764-775
    発行日: 1979/08/20
    公開日: 2008/03/19
    ジャーナル フリー
    A case of Louis-Bar's syndrome (ataxia telangiectasia) in a 9-year-old girl was presented and * study was made of the nature and origin of oculomotor abnormalities in association with the syndrome.
    1. Nature of the oculomotor abnormalities
    The following abnormalities were observed: 1) hypometric saccades; 2) difficulty of keeping eye position (notably non-central gaze); 3) coarse fixation jerks; 4) downward vertical nystagmus elicited on lateral gaze; 5) weak convergence; 6) suppression of optokinetic nystagmus; 7) disturbance of smooth following eye movements; 8) Roth-Bielschowsky sign; 9) flutter-like oscillations of the eye (Cogan). In addition to these, fixation nystagmus is also reported in the literature. To be noted is that the symptoms 3), 7) and 9) are entirely new additions to the ocular manifestations of this syndrome.
    2. Origin
    Aside from these oculomotor abnormalities, conspicuous cerebellar symptoms were the only neurologic manifestations in the present case. Along with recent demonstration that the pathology of the central nervous system of the syndrome is characterized by diffuse atrophy occurring almost within the confines of the cerebellum or at least by the absence of significant lesions in the brain stem and cerebrum, it was suggested that the oculomotor abnormalities mentioned above are all of cerebellar origin. In this connection, special reference was made to the symptoms 5), 6), 8) and 9).
  • 坂井 真, 三宅 浩郷, 新川 敦
    1979 年 82 巻 8 号 p. 776-784
    発行日: 1979/08/20
    公開日: 2008/03/19
    ジャーナル フリー
  • 沖津 卓二, 河本 和友, 金子 豊, 湯浅 涼
    1979 年 82 巻 8 号 p. 785-792
    発行日: 1979/08/20
    公開日: 2008/03/19
    ジャーナル フリー
    Using the impedance audiometry, screening of children in the first grade of an elementary school was performed. The children were investigated with pure tone andiometry, impedance audiometry and otoscopy. Screening using pure tone audidnetry was performed at frequencies of 1 and 4 kHz. The hearing threshold more than 20 dB HL was considered pathological in one or both of the frequencies. Screening impedance audiometry was performed with the Madsen impedance bridge ZO 70 (probe tone 220 Hz) and the pressure in the external ear canal was variated from -400 to +200 mmH2O. The screening was performed by tympanometry and measurement of acoustic impedance or static compliance. Out of 145 children, 6 children (4. 1%) with secretory otitis media were discovered by impedance audiometry. Out of these 6 cases, only one was found by pure tone audiometry. Five out of these six children had no subjective symptoms. The results indicated that the screening using impedance audiometry (tympanometry) was more efficient than the screening using pure tone audiometry and otoscopy in the detection of secretory otitis media. In this study, some problems, such as cost of the instrument, time-consumptiveness and high over-referral rate, were pointed out to introduce the impedance audiometry for school screening. However, tympanometry is recommended as a complement of pure tone screening in screening of children.
  • その分類に関する一提案
    船坂 宗太郎, 牛嶋 達次郎, 矢野 純
    1979 年 82 巻 8 号 p. 793-798
    発行日: 1979/08/20
    公開日: 2008/03/19
    ジャーナル フリー
    Ten ears of congenital ossicular fixation without deformities of the external ear were presented. They were classified into two groups, three ears with malleus and/or incus fixation and seven with stapes fixations. The surgical treatment for the former group was to remove the axed part of the ossicles for the two ears and to mobilize the ossicle for the remained one. The removal of the fixed part yielded satisfactory results, but the mobilization failed to improve the hearing. Stapedectomy and the gelfoam wire prosthesis were performed for the group of stapes fixation. The result was relatively good in some cases with the normal shaped stapes, but it was not satisfactory in other cases with the malformed stapes.
    It was conjectured from the embryogenetic consideration that the malleus and/or the incus fixation was the results of disturbances in separation process by the undifferentiated mesenchyme surrounding the ossicles, and the stapes fixation was caused by maldevelopment of the stapedial lamina.
    The authors insist that this classification is practically valid as it would suggest the maldeveloped point in ossicular genesis and results of surgical treatment.
  • 加勢 満
    1979 年 82 巻 8 号 p. 799-813
    発行日: 1979/08/20
    公開日: 2008/03/19
    ジャーナル フリー
    Using primarily and continuously cultured lymphocytes from tonsils, various factors causing the changes of occurrence in sister chromatid exchanges (SCE) together with the chromosomal aberrations (CA) were examined. The most optimal culture conditions for the SCE observation were studied in primary tonsillar lymphocytes and determined as follows: The number of cells at initiation was; 2 X 106 cells/ml, the culture medium was RPMI-1640 containing 20% fetal calf serum, 15pg/ml of phytohemagglutinin-P and 1011g/ml of 5-bromodeoxyuridine (BUdR) ; the incubation period was 72 hours at 37-C. During 72 hours, the most of cells performed two rounds of DNA replication and showed the metaphases in which each chromosome had one chromatid unifilarly substituted with BUdR and one bifilarly. These cells were submitted to the fluorescence plus Giemsa technique (FPG) for the SCE observation following the usual procedures for chromosomal analysis (flame-drying method).
    The mean number of SCE in primary tonsillar lymphocytes from 13 patients showing tonsillar hypertrophy or recurrent tonsillitis without inflammatory signs was 5. 134-0.16 SCEs/cell, while 6.57-0. 15 SCEs/cell in 14 patients with chronic inflammatory tonsils. No significant changes of the SCE scores related to the ages, the grades of hypertrophy and the mitotic indices were observed.
    In the case of tonsillar lymphocytes infected by Epstein-Barr virus (EBV), the SCE scores showed the similar values to those in the chronic tonsillitis. The treatment of these cells with an antitumor drug (mitomycin C), u chemical mutagen (4-nitroquinoline 1-oxide) and the irradiation with ultraviolet light induced significantly the increases of SCE scores before the chromatid breaks occured. Caffein known as the specific inhibitor for DNA repair enzyme increased the breaks without the SCE changes. Nicotine which seems to be related to generation of lung cancer did not show any effects on the SCE or break changes even at 10-3 M. The infection by several DNA-viruses (adeno type 5 and 12, cowpox) or RNA-viruses (rubella, Sendai and Coxsackie B-5), which induced oral or upper respiratory tract infection did not cause the significant changes of SCE scores. However, it resulted in the increases of the breaks before the viral cytopathogenic effect was appeared.
    These results seem to indicate that the analysis of SCE and CA in tonsillar lymphocytes may be a useful procedure for the follow-up of the minor action of chemical mutagens and the initial change by viral infection with the other cellular responses.
  • 三橋 重信, 平野 実
    1979 年 82 巻 8 号 p. 858-861
    発行日: 1979/08/20
    公開日: 2008/03/19
    ジャーナル フリー
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