日本耳鼻咽喉科学会会報
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
94 巻, 2 号
選択された号の論文の16件中1~16を表示しています
  • 空間認知による固視,歩行の制御
    高橋 正紘, 岡田 行弘, 斉藤 晶, 武井 泰彦, 竹内 泉, 神崎 仁, 富沢 郁子, 宇山 啓子
    1991 年 94 巻 2 号 p. 161-169
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    We reported a new theory for daily vestibular functions which advocates top-down regulation of posture and gaze by supposing the coordinates in the brain. The hypothesis consists of three principles ; first, the vestibular system is primarily a sensory system to detect spatial orientation ; second, multisensory integrations reconstruct three-dimensional coordinates in the brain, which ascertain spatial orientation ; third, daily behaviours like gazing or walking are controlled in a feed -forward manner by programming on the coordinates in the brain. The hypothesis was useful to understand strategic differences between active and passive movements, to distinct gaze control from ocular reflexes, to apply the rules of gaze control to posture control, and to clarify the mechanism to produce motion sickness.
  • 隈上 秀高, 中島 成人, 崎浜 教之
    1991 年 94 巻 2 号 p. 170-176
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    Five patients with juvenile nasopharyngeal angiofibroma were found between 1984 and 1990 in our department. Clinical findings, treatment, and postoperative follow-up were reported. Two patients belonged to stage III and remnant 3 patients belonged to stage I. In cases of stage I, a surgical approach through the suprahyoid pharyngotomy was a worthy procedure to try, because angiofibroma was observed under direct vision and hemostasis was easy. In therapeutic planning, the authors emphasized the need of a preoperative staging classification based on CT scanning and selective angiography. In immunohistochemical studies, Langerhans cells with S-100 protein positive were found. Fibroblasts revealed estradiol positive but testosterone showed negative in all cases. Thus, juvenile nasopharyngeal angiofibroma was considered to be neoplasm related estradiol.
  • 正常耳,中心穿孔を伴う単純化膿性中耳炎,真珠腫性中耳炎の比較
    山岨 達也, 菊地 茂, 竹内 直信, 原田 勇彦, 野村 恭也
    1991 年 94 巻 2 号 p. 177-182
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    The structures of the anterior epitympanic recess and its surrounding tissues were examined among non-inflammatory ear, chronic otitis media with central perforation and cholesteatoma, using axial scans of high resolution computed tomography.
    The length and width of the recess, as well as the number of the slices where the cog was determined, had no significant differences among them. Thus, the bony structure of the recess was considered to be seldom influenced by inflammatory processes.
    In the non-inflammatory ear, the degree of pneumatization around the recess was similar to that of the petrous apex cells and lower than that of the mastoid cells. In the chronic otitis media with central perforation and cholesteatoma, the pneumatization of the whole temporal bones was suppressed and the tendency was also found that the cells around the recess were less pneumatized than the mastoid cells.
    When cholesteatoma invaded into the anterior epitympanic recess, the destruction of the bony protrusion of the lateral wall between the recess and the epitympanum was recognized, as well as the disappearance of the cog. The bony protrusion was considered to be an inferior extention of the cog toward the anterior tympanic spine.
  • 村上 泰, 安田 範夫, 斉藤 裕子, 任 書熹, 中井 茂
    1991 年 94 巻 2 号 p. 183-191
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    In order to obtain a more objective method to evaluate epithelial disorders and carcinomas of the hypopharynx, the expression pattern of cytokeratins (CKs) was investigated by ABC technique using several kinds of monoclonal antibodies that react monospecifically with each subclass of CKs.
    In normal epithelia, CK-19 was strongly positive in the basal layer but apparently reduced in suprabasal layers and completely negative in superficial layers, while CK-13 showed a striking contrast to CK-19, being expressed within the whole thickness of epithelia except only in the basal layer.
    These 2 subclasses were also observed in " abnormal " epithelia, and characteristic changes of their combination were demonstrated in proportion to the histological gradings.
    In invasive carcinomas, CK-19 was strongly positive in all carcinoma cells of poorly differentiated carcinomas. It was sporadically positive in moderately differentiated carcinomas, the more differentiated the more sporadic. It was completely negative in well differentiated carcinomas. CK-13, on the other hand, was negative in poorly differentiated carcinomas but positive in keratinized cells of moderately or well differentiated carcinomas. Strong expression of CK-1 was observed only in well keratinized cells of hyperkeratotic epithelia and well differentiated carcinomas.
    These characteristic findings are consistently observed in all samples and, then, may be useful in evaluating epithelial disorders and carcinomas of the hypopharynx, when used in conjunction with standard histological techniques. It seems most likely that these results play a part in investigating normal and abnormal processes of cell differentiation.
  • 田中 信三, 平野 実, 松岡 秀隆, 井上 要二郎, 田井 良明
    1991 年 94 巻 2 号 p. 192-197
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    The complications and swallowing functions were studied in eleven patients who had undergone free jejunal autograft reconstruction after total pharyngolaryngectomy and cervical esophagotomy.All patients have had advanced cancers of the hypopharynx or cervical esophagus. Fistulla was complicated in three patients (27%), including one (9%) who died of pneumonia. Death or graft necrosis was not complicated in perioperative period. There was no patient with stenosis.Radiation necrosis of the graft and skin occured six monthes after post-operative 60 Gy irradiation in one patient. Ten patients of 11 regained swallowing function. An oral diet was started between 9 and 50 post-operative days, with an average of 19 days. The duration of a diet was from 20 to 60 minutes (mean : 37 to 40 minutes). Five patients could take a normal diet, while the another five ate gluel or liquid food. The free jejunal graft reconstruction of pharyngoesophagus was highly safe reliability and an advantage in an early recovery of swallowing function, but it had some problems with regard to post-operative irradiation and swallowing.
  • 斎藤 晶, 高橋 正紘, 岡田 行弘, 武井 泰彦, 竹内 泉, 宇山 啓子, 富沢 郁子, 神崎 仁
    1991 年 94 巻 2 号 p. 198-202
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    We observed locomotion and motion sickness in 10 normal adults wearing reversing goggles while moving outdoors.
    Horizontal reversal of the visual field produced moderate to severe ataxia and motion sickness in all subjects except one. There was marked variability in the sensitivity among different subjects. In contrast, vertical reversal produced no symptoms.
    Confusion of information relation to spatial orientation possibly caused both the motion sickness and abnormal locomotion. Horizontal reversal of visual information produces disorientation because visual information is equal in importance to that from the semicircular canals. In the case of vertical reversal of visual information, orientation may be assured by gravity. The present study suggests that motion sickness is a biological signal alerting the organism to loss of spatial orientation rather than a mere autonomic symptom produced by mismatched sensory information.It appears that motion sickness is accompanied by dysequilibrium and abnormality of locomotion.
  • 河野 正樹
    1991 年 94 巻 2 号 p. 203-207
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    One hundred and sixty four ENT patients were observed at the Kashima village hospital located on the remote, isolated islands (Islands of Koshiki), Kagoshima prefecture, during two years of April 1987 to March 1989. They were composed of the following conditions ;
    1. Of the 164 individuals, 46 cases, showing 28. 1% were admitted from the other inconvenient districts.
    2. About a half of all the patients with acute infectious diseases might be treated by their home doctors.
    3. The patients required operative care were contained in the individuals with chronic inflammatory diseases.
    4. Most of the cases with acute otitis in summer were caused by naked diving to catch the fishes in these islands.
    5. The incidence of the chronic ENT diseases such as perceptive hearing disturbances including the presbyacusis, chronic otitis media, chronic sinusitis, and laryngopharyngeal paresthesia in order, were the same as one of the previous reports in the other remote isolated islands.
    All the general practitioners worked in the remote isolated islands should be necessary to have a special training of fundamental knowledges and clinical skills in otolaryngology.
  • 今手 祐二, 兼定 啓子, 金谷 浩一郎, 関谷 透, 亀井 敏昭
    1991 年 94 巻 2 号 p. 208-213
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    A case of the localized laryngeal amyloidosis was reported. The patient was a 51-year-old female who complained of hoarseness for about a year. Pathological study on the biopsy specimen taken from both the subglottic area under laryngeal microsurgery showed the deposit of amyloid.Laryngeal microsurgery showed the deposit of amyloid at bilateral subglottic area. Electron microscopic study disclosed a typical amyloid fibrillar structure. Amyloid protein, in this case, was confirmed as protein AA appeared through the potassium permanganate treatment and immunoperoxidase technique (ABC method).
  • 酒井 俊一, 森 望, 宮口 衛, 伊東 真人
    1991 年 94 巻 2 号 p. 214-224
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    We had a total of 372 patients with maxillary carcinoma in the period from 1972 to 1983. 108 patients were treated with 50Gy irradiation, intraarterial infusion of 2000mg 5-FU and extensive Denker's operation in combination. 222 patients were treated with 50Gy. irradiation and intraarterial infusion of 2000mg 5-FU. The remaining 42 patients were treated with radio-therapy alone.
    The 5-year survival in these three groups was 48%, 43%, and 17%, respectively. The cumulative local control of the two former groups was 51%, and 33%, respectively. Total maxillectomy was performed as a second treatment only in 24 of 108 patients (22%) of the first group. Nine of them survived for 5 years and 15 died. On the other hand, 84 of 108 patients not treated with total maxillectomy consisted of 41 five year survivors and 43 deads. From the above, we believe that extensive Denker's operation plays a role to increase success rate of initial treatment, decrease in the necessity of total maxillectomy and improve survival rate, but its indication is limited.
  • 趙 榮祥, 佐藤 公則, 平野 実
    1991 年 94 巻 2 号 p. 225-230
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    A series of 60 cases (85 vocal folds) with epithelial hyperplasia of the vocal fold were statistically analysed between the clinical findings and histologic types to identify the significant factors predicting the presence or absence of atypia in the lesion. The factors of age, sex, appearance of the lesion, extent of the lesion and degree of limitation of vocal fold vibration showed significance and therefore were scored respectively for further analysis from -1 to +1 according to the possibility of atypia from low to high. More than half of the group without atypia had total score of 0 or less, while more than half of the group with atypia had total score of +4 or more. The difference between two groups was significantly high (p<0. 01). This results showed that if total score was 0 or less the possibility of atypia was very low and conservative treatment including discontinuation of smoking and follow-up can be conducted, whereas if total score was +4 or more the possibility of atypia was very high and a proper biopsy followed by laser surgery is indicated.
  • ホログラフィ干渉法による実験的研究
    前田 学
    1991 年 94 巻 2 号 p. 231-240
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    Using canine temporal bone, perforations were surgically prepared at the anterior, inferior and posterior parts of the tympanic membrane, and the influences of these perforations on the tympanic vibration were observed and analyzed by holographic interferometry.
    Normal canine tympanic membrane had its respective single maximum amplitude points at its anterior and posterior parts at a frequency from the low compass to 2 kHz or so and showed a cocentric circular vibration pattern centering mainly there around. At 3 and 4 kHz or so, the posterior and anterior parts began to show their respective sectional vibrations and with an increase in frequency, showed their further complicated multi-sectional vibrations. Resonance frequency was 1 or 2 kHz or so. The tympanic vibration following the preparation of perforations was as follows :
    1) For the posterior perforation, the frequency at which the anterior sectional vibration began passed to a higher frequency, while for the other perforations, no change was noted in vibration pattern of the remaining tympanic membrane.
    2) Comparative examination of the vibration amplitude at the mallear tip revealed that for a small perforation, no change in resonance frequency was noted regardless of the location of perforation and an increase in vibration amplitude was noted near the resonance frequency.
    3) For the anterior perforation, no change in resonance frequency was noted even with an expansion of perforation and an increase in vibration amplitude was noted near the resonance frequency.
    4) For the posterior and inferior perforations, the resonance frequency passed to a higher frequency with an expansion of perforation and an increase in vibration amplitude was noted near the resonance frequency.
    5) For any one of the perforations, the vibration amplitude of the low frequency area was inhibited, and with an expansion of the perforation, the inhibition of vibration amplitude was noted up to a higher frequency.
  • 和田 佳郎
    1991 年 94 巻 2 号 p. 241-250
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
    Motion sickness may be defined as an abnormal body response caused to certain kinds of motion in normal subjects. Although we know etiologic factors and symptoms of motion sickness, the mechanism of motion sickness remains unknown. To clarify some characteristics of motion sickness in rabbits, we observed responses of the autonomic nervous system consisting of a change in heart rate (HR), coefficient of variation of R-R interval (CV-RR), and serum adrenaline (AD)-and free fatty acid (FFA) concentrations during linear oscillatory acceleration and/or optokinetic stimulation. The following results were obtained as
    1. Although transverse and vertical linear oscillatory accelerations affected little the body responses, longitudinal linear oscillatory acceleration diminished HR and increased CV-RR and FFA.
    2. Since injection of atropine or labyrinthectomy reduced the changes of HR and CV-RR induced by longitudinal linear oscillatory acceleration the responses may originate from the vestibulo-parasympathetic nerve reflex.
    3. An increase of FFA during longitudinal linear oscillatory acceleration indicates that sympathetic nerve as well as parasympathetic nerve activities are elevated.
    4. In this study optokinetic stimulation was not so influential as linear oscillatory acceleration for provoking motion sickness in rabbits.
    5. Concomitant stimulations of optokinetic and vestibular inputs enlarged variations of these responses.
  • 太田 文彦
    1991 年 94 巻 2 号 p. 268-269
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
  • 藤本 吉秀
    1991 年 94 巻 2 号 p. 270-271
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
  • 第18回日本臨床耳科学会
    茂木 五郎
    1991 年 94 巻 2 号 p. 272-273
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
  • 坂田 英治
    1991 年 94 巻 2 号 p. 274-275
    発行日: 1991/02/20
    公開日: 2008/03/19
    ジャーナル フリー
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