巻号一覧
後続誌
前身誌
84 巻, 12 号
選択された号の論文の8件中1～8を表示しています
- |<
- <
- 1
- >
- >|
-
瘻管洗滌 染色法と顕微鏡下全摘術関谷 透, 大山 英樹, 松尾 隆晶, 平田 哲康, 奥園 達也1981 年 84 巻 12 号 p. 1529-1535
発行日: 1981/12/20
公開日: 2008/03/19
ジャーナル フリーIncomplete excision of the infected congenital auricular fistula is often accompanied by formation of a draining sinus and by formation of the bizzare scars. Branching of the fistula often makes total excision difficult.
There are several cases who were treated with a careless incision and draining of the infected fistula by general physicians or pediatricians and sometimes even by otolaryngologists.
The purpose of this paper is to emphasize the following: 1. conservative management of the infected fistula could be done by an irrigation in the fistula sinus with saline solution and diluted antibiotics solution. 2. repeated injection of dyes such as methylene blue, indigo carmine into the tract prior to surgery may be helpful in defining its extent. 3. complete excision of the stained fistula was done meticulously under surgical microscope.
The cases with infected auricular fistula with draining sinus after the first incision and drainage were reported, and a literature review was made with a brief comment on its conservative and surgical managements.抄録全体を表示PDF形式でダウンロード (2449K) -
柴原 義博, 沖津 卓二, 金子 豊, 佐久間 真弓, 河本 和友1981 年 84 巻 12 号 p. 1536-1541
発行日: 1981/12/20
公開日: 2008/03/19
ジャーナル フリーIn our previous study, it was emphasized that impedance screening was more efficient than the pure tone screening and the otoscopy for identifying middle ear pathology. On the other hand, it was also pointed out that there were some problems, such as time-consumptiveness and high over-refferal rate to introduce the impedance screening for school children.
The present study was undertaken to ascertain whether the impedance screening was actually more effective than the other tests (audiometry and otoscopy) for identifying middle ear diseases and to investigate some methods to resolve those problems reported previously by the authors.
One hundred and ninety children in the first grade of an elementary school were examined with otoscopy, screening audiometry and impedance audiometry (tympanometry). In this time, impedance screening was performed with the tympanometer (American, Model 85 AR) which could illustrate a tympanogram automatically.
Impedance screening was indeed more efficient than the pure tone audiometric and otoscopic screening in detection of ear desease, mainly otitis media with effusion. Furthermore, impacted cerumen and perforation of drum were picked up by impedance audiometry. Beside all abnormal cases detected by otoscopy, individuals who passed the otoscopy but were in need of otologic evaluation by physician could be selected with impedance screening. It was demonstrated that the over-referral rate (57%) could be reduced to about 20% when two repeat impedance tests were imployed or pass/fail criteria for impedance screening was changed. Testing time for impedance screening could be shortened considerably using the tympanometer equipped with automatic recorder.
Findings from our study suggest that introducing the impedance audiometry for school screening improve the efficiency of ENT screening for school children.抄録全体を表示PDF形式でダウンロード (448K) -
聴性脳幹反応と温度眼振反応を指標として馬場 俊吉1981 年 84 巻 12 号 p. 1542-1553
発行日: 1981/12/20
公開日: 2008/03/19
ジャーナル フリーFifty-five comatose patients were examined by means of the auditory brainstem response (ABR) and the caloric vestibular tests. The causes of coma were: head injury, subdural hematoma, intracranial hemorrhage, cereberal thrombosis, etc. The brainstem function of these patients was evaluated by these two tests and the relationship between the results of theseresponses and the prognosis of the patients was investigated.
ABR findings were classified into four groups, i. e. normal response, slight and severe prolongation of inter wave latency (I-V), and no response including partial disappearance of the waves. Ten among 21 patients who showed normal ABRs at the first examination which was performed mostly within 24 hours after the onset of coma, died eventually. All of the 14 patients also died, who showed no response at any time after admission.
The responses of the caloric vestibular test were also classified into four types, i. e. normal response (slow deviation with quich return of the eyes), nystagmoid reaction (slow deviation with slow return), eye deviation (conjugate ocular deviation without returning), and no response. In all the patients who recovered, the results of the caloric vestibular response were clearly better than those who finally became vegetative or died. However, 3 patients among 30 who showed no response at the first examination also recovered.
All the patients who exhibited no response both in ABR and caloric vestibular test at any time of their course, died eventually.
From these results it can be concluded that the ABR and caloric vestibular tests were useful for evaluating the brainstem function and predicting the prognosis of comatose patients.抄録全体を表示PDF形式でダウンロード (1526K) -
CSF産生腫瘍東家 倫夫, 黒田 建彰, 大渕 正博, 猪川 勉, 土生 健二郎, 石川 哮1981 年 84 巻 12 号 p. 1554-1561
発行日: 1981/12/20
公開日: 2008/03/19
ジャーナル フリーA case, 50 year old male, of CSF (Colony Stimulating Factor) producing maxillary cancer was reported. His chief complaint was the remarkable swelling of the left cheek. Granulomatous tumor grew in the maxillary sinus and developed mainly to anterior-lateral direction. Histological diagnosis of the tumor was undifferentiated carcinoma.
Laboratory data showed marked leukocytosis and hypercalcemia. The white blood cell count was 67, 400/mm3 with 91% mature neutrophils. The results of sternal puncture did not indicate any supporting findings of the leukemia. There was no apparent sign of infection except for slight fever and positive CRP.
Surgical removal of the tumor resulted rapid decrease of WBC count at the level of 10, 000/mm3. The following radiation therapy also maintained it at the level of 10, 000 to 20, 000/mm3. However, a few weeks after finishing of the radiation therapy, the tumor began to growing again. And WBC count was gradually increased in parallel with tumor size. The other interesting finding was that the serum calcium level was also well correlated to the tumor growth.
The results suggested that the tumor might produce some stimulating factors of leukocyte proliferation. There have been only several reports that a particular case of cancer produce so called colony stimulation factor (CSF). The authors, therefore, investigated to detect the CSF in patient's urine and serum, and supernatant from short-term culture of the tumor. A higher level of CSF was detected in the urine but not in the serum and culture supernatant.
From these results and clinical feature, it could be considered that this cancer was so-called CSF producing tumor.
It is said that the case with CSF producing tumor commonly shows hypercalcemia, as detected in our case. The hypercalcemia in the case reported, seemed to be caused by CSF related factor.抄録全体を表示PDF形式でダウンロード (1415K) -
三好 彰1981 年 84 巻 12 号 p. 1562-1569
発行日: 1981/12/20
公開日: 2008/03/19
ジャーナル フリーThree depressive patients who complained discomfort of throat were reported.
The first case had "Selbstmordversuch", but was afraid of visiting or being released to a psychiatrist.
The second and the third case had the past history of psychiatric treatment.
The third case was not satiated by a psychiatrist because of the doctor's less communicative attitude.
They made favorable progresses after the treatment in Department of Otolaryngology. Recently, the number of depressive patients seems to be increasing, and there are some cases as such the treatment by psychiatrist is not always satisfactory.
In this paper, the author wants to stress the importance of diagnosis and treatment for depressive patients in ENT clinic.抄録全体を表示PDF形式でダウンロード (635K) -
1. 頭頸部扁平上皮癌細胞の培養猪川 勉1981 年 84 巻 12 号 p. 1570-1578
発行日: 1981/12/20
公開日: 2008/03/19
ジャーナル フリーTo investigate the immunological cytotoxicity in human autologous system, we tried to culture squamous cell carcinoma in vitro and successfully established a maxillary cancer cell line. Twenty seven cancer tissues obtained surgically were prepared. Primary growth of tumor cells was successful in sixteen out of the 27 cases. Three out of the 16 cases were successfully transfered to passage, but the number of tumor cells in 13 cases gradually diminished, due to remarkable growth of fibroblasts. After 4 months of the establishment of primary culture, 2 of them were contaminated by fungal organisms. Finally, one case of maxillary cancer, which has still been in culture for nearly 1 year and 9 months (32nd serial subpassage), was established as a cell line of squamous cell carcinoma (KOIMC-011). Ultrastructual observation, chromosomal analysis, growing status and immunological features on cell surface confirmed the successful establishment of the cell line.抄録全体を表示PDF形式でダウンロード (2148K) -
2. 自己リンパ球の癌細胞障害性の証明猪川 勉1981 年 84 巻 12 号 p. 1579-1587
発行日: 1981/12/20
公開日: 2008/03/19
ジャーナル フリーMany investigators reported the induction of the tumor-specific cytotoxic T lymphocytes both in vivo and in vitro in syngeneic animals. However, few reports are found on human autologous cytotoxic T cell induced by the stimulation with cancer cells.
In vitro induction of human autologous cytotoxic T cells was attempted using a squamous cell carcinoma cell line established in our laboratory (KOIMC-011), which was originated from a patient with maxillary cancer. The patient is now clinically free from carcinoma. The cultured cells were used as stimulating antigen and as target cells.
Autologous cytotoxicity was markedly induced when the peripheral lymphocytes of this patient were incubated with mitomycin C-treated cancer cells for 5 days. The cytotoxic activity was found in E-rostte forming lymphocytes and was blocked when treated with monoclonal antihuman LEU-2A antibodies. The activity remained unchanged when treated with aggregated human or rabbit IgG, or incubated with cold K562.
These results suggest that the tumor-specific cytotoxic T lymphocytes contribute to the induction of cytotoxicity against cultured squamous cell carcinoma in human autologous system.抄録全体を表示PDF形式でダウンロード (737K) -
尾股 丈夫, 小針 啓生, 相川 通, 大槻 好正, 大谷 巌, 大内 仁, 竹中 正之, シエッツレ ワルター1981 年 84 巻 12 号 p. 1588-1594
発行日: 1981/12/20
公開日: 2008/03/19
ジャーナル フリーTwenty-six rabbits were exposed to a pure tone of 2kHz, 100dB for 2 hours, and were devided into five groups. Group I: immediately decapitated after acoustic exposure. Group II: decapitated 3 days after. Group III: decapitated 7 days after. Group IV: decapitated 14 days after. Group V: decapitated 30 days after. Five rabbits were used as control. The timedepending changes of the infranuclear regions of the outer hair cells of these animals were observed with an electron microscope. As the results the outer hair cells were classified, according to the histological findings, into the following groups. Normal cells, enhanced cells (small vesicles and free ribosomes were increased in number and the electron density of the matrix became higher) and reduced cells (small vesicles and free ribosomes were decreased and the electron density of the matrix became lower). Normal cells were 25% in the group I, 30% in the group III, 45% in the group IV and 60% in the group V. Enhanced cells were 8% in the group I, 7% in the group III, 3% in the group IV and 4% in the group V respectively. Reduced cells were 67% in the group I, 63% in the group III, 42% in the group IV and 36% in the group V.抄録全体を表示PDF形式でダウンロード (2790K)
- |<
- <
- 1
- >
- >|