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84 巻, 8 号
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ヒト胎児における組織学的観察松村 元良1981 年 84 巻 8 号 p. 815-825
発行日: 1981/08/20
公開日: 2008/03/19
ジャーナル フリーThe development of the facial nerve and its canal in the temporal bone was histologically investigated with serial sections in connection to the middle ear sugery.
Materials used were 56 Japanese human embryos and fetuses aged from the 4th to the 23rd week (3.3 to 330mm in CR or CH length) that were stored in the Human Embryo Center for Teratological Studies of Kyoto University and Department of Otolaryngology, Okayama University Medical School. The results were as follows:
1) The second arch epibranchial placode seemed to play an important role in the development of the geniculate ganglion.
2) A trunk of the facial nerve, chorda tympani nerve and N. petrosus major accomplish before the ossicles appeared at the 6th week.
3) The facial nerve was rapidly differentiated as the internal meatal, horizontal and vertical segments as with the development of the primordial stapes at the stage 17 and was gradually completed its normal running course by both the differentiation of the cartilagenous otic capsule and the pneumatization of the primitive tympanic cavity during the whole intra-uterine period.
4) The development of the facial canal began as a sulcus on the canalicular division of the precartilagenous otic capsule at the stage 21. The formation of the tympanic boundary of the horizontal segment until the 22nd week of fetal life.
5) Anson's hypothesis in which the head of malleus and the body of incus are made from Meckel's cartilage, and the handle of malleus and the long process of incus from Reichert's cartilage was supported.
6) The rate of the thickness of the facial nerve to the diameter of the facial canal was large at the horizontal segment, but it was small at the vertical segment.抄録全体を表示PDF形式でダウンロード (4712K) -
全副鼻腔手術と視神経管開放術の経験仁保 正和1981 年 84 巻 8 号 p. 826-835
発行日: 1981/08/20
公開日: 2008/03/19
ジャーナル フリーFour patients of eye lesions due to postoperative muco-pyoceles of the nasal accessory sinuses were reported. Two patients with exophthalmus received a pansinectomy. Another two patients with blindness received decompression of the optic canal through the trans-ethmoidal route (S. Niho) after a pansinectomy. The walls of muco-pyoceles were stripped off. Their postoperative courses were observed from the second to the sixth year.
Patients with exophthalmus associated with slight retrobulbar optic neuritis returned to their normal levels. One patient obtained a slight recovery of her visual acuity, although surgery was carried out 16 days after she lost her visual acuity. As mucocele of the sphenoid sinus had not destroyed the optic nerve, the cause of lesions of the optic nerve was thought to be pressure. The lost visual acuity is not always a destruction of the optic nerve. The other patients with pyocele did not recover visual acuity. Pyocele had largely worn the optic canal and the optic nerve had showed marked edematous swelling. As regards an indication of decompression of the optic canal, these results led to the suggestion that a recovery from lost visual acuity could be expected when the optic canal was not worn. As the orbit was protected by the Niho hook, orbit lesions and meningitis did not occur.
Likewise, the degree of changes and symptoms of chronic sinusitis were severe. Olfaction was markedly impaired. Chronic inflammation and cysts were observed in all sinuses including the other sides of the nasal accessory sinuses. Inasmuch as all inflammatory changes in the sinuses were removed as much as possible, clinical changes and subjective symptoms were markedly improved.抄録全体を表示PDF形式でダウンロード (2115K) -
第1報 臨床的および免疫学的検討とその文献的考察志藤 文明, 森本 賢治, 三部 重雄, 山中 昇, 形浦 昭克1981 年 84 巻 8 号 p. 836-849
発行日: 1981/08/20
公開日: 2008/03/19
ジャーナル フリーA 77 year-old male visited the Sapporo Medical College Hospital in February, 1980, complaining a tumor in the left posterior faucial pillar. Biopsy findings of the tumor revealed submucosal proliferation of pleomorphic plasma cells, but plasma cell did not increase its number in the bone marrow smear. The lesion was diagnosed as a extramedullary plasmacytoma of the pharynx and detailed examinations revealed that the patient was also suffering with pulmonary infiltration with eosinophilia and plasma cell dyscrasia.
Although there was no increase in serum M-protein, a kappa type Bence-Jones protein was demonstrated in the concentrated urine specimen by immunoelectrophoretic method. An intracytoplasmic monoclonal immunoglobulin (type IgA-kappa) was also demonstrated by immuno-histochemical method in the tumor cells.
We reviewed seventy-five cases with plasmacytoma of the head and neck region in the Japanese literature and found that five of these cases should be classified as the metastatic lesions of multiple myeloma, and four other cases were the solitary plasmacytoma of bone. Sixty-six of the reported cases were the "true" extramedullary plasmacytoma of the head and neck region and our case was found to be the eighth case located in the pharyngeal region.
The patient is free of disease after treated by the combination of surgery and radiation therapy.抄録全体を表示PDF形式でダウンロード (3043K) -
岡 嗣郎1981 年 84 巻 8 号 p. 850-857
発行日: 1981/08/20
公開日: 2008/03/19
ジャーナル フリーMany of the patients of olfactory disturbance complained that they could smelled in a moment but the smell decreased rapidly. This phenomenon seemed that it caused of the olfactory fatigue. In this study, the relationship between olfactory fatigue and olfactory acuity was investigated for make clear this afternoon.
The subjects of this study were 52 normal adults. The odorous for stimulus were CYCLOTENE and iso-VARELIC ACID which were the odorous of T & T olfactometer.
The growing and recovering time of olfactory fatigue was measured under the following condition. The olfactory test paper was moisted with odorous and took placed nearly 1cm from the nasal tip of each subject. Subjects were blindfolded and took smelled of the odorous on test paper under rested respilation. A level of concentration of odorous was higher than that of the level in the subject. In the first inspection, the subjects were not explained about the difference. In the third inspection, the condition was the same of the second one, but two of different concentration odorous were used.
Results obtained were as follows:
In the first inspection, the measuring time of growing and recovering were fallen to pieces. In the second inspection, subjects were explained about both thresholds difference completely, so the data were not so fallen to pieces. In the third inspection, the time of growing and recovering at high concentration odorous was longer than that at low concentration odorous. Even though the data of second and third inspection were fallen to little pieces, but the ratio of growing time of fatigue in detection and recognition of several subjects were constant, which was 1.6.
Therefore, it seemed that the data pieces were not originated in inspection method but in the structure of nasal cavity and the secretion of olfactory mucous membrane of several subjects. The data from third inspection were plotted on the graph and made the fatigue alteration with time of both concentrations. The fatigue at high concentration got rapidly in first term of fatigue, but changed inactive near in threshold level. The recovering rate of fatigue from detection to recognition were more rapid at high-concentration than lows.
From the facts described above, the phenomenon that "patients could smelled in a moment but the smell decreased rapidly" were seemed that it originated in olfactory fatigue. Therefore, the investigation of this phenomenon in patients was very useful for diagnosis and treatment of olfactory disturbance.抄録全体を表示PDF形式でダウンロード (2090K) -
今井 昭雄, 中野 雄一, 宮尾 益征, 富樫 孝一, 小西 和朗, 白石 輝雄, 椎名 睦郎, 井口 正男1981 年 84 巻 8 号 p. 858-867
発行日: 1981/08/20
公開日: 2008/12/15
ジャーナル フリーFour cases of necrotizing osteomyelitis of the temporal bone were reported. These patients had had chronic suppurative otitis media from childhood. On a certain occasion, acute granulomatous inflammation with bone erosion occured and necrosis of the temporal bone was progressive continuously to the occipital bone, despite the administration of antibiotics and repeated surgical debridement.
One of four cured, however, two expired of bacterial meningitis and one died of gastric cancer.
The authors expected that the nature of the disease was the synergism of aerobic gram negative rods and anaerobic bacteria. This type of the disease should be called attention as a severe complication of otitis media.抄録全体を表示PDF形式でダウンロード (3340K) -
3年治癒とその治癒に影響する臨床的,病理組織学的因子について高橋 廣臣, 岡本 牧人, 鈴木 徹, 斎藤 彰, 八尾 和雄, 池上 彰博, 古川 浩三, 八木 拓, 代田 正道, 新美 成二1981 年 84 巻 8 号 p. 868-876
発行日: 1981/08/20
公開日: 2008/03/19
ジャーナル フリーIn this study, we evaluated 39 patients with maxillary carcinoma who were treated in our Hospital from July, 1971 to February, 1978. The patients who were also treated during the same period but died of other diseases were excluded from present study.
Twenty-six of them are alive over three years. The factors which may have influences on the result of our treatment are summerized as follows:
1.The prognosis of the patients under 49 years of age was worse than that of the patients over 50. The prognosis of male patients was worse than that of female.
2. The posterior wall destruction of the maxillary sinus had no apparent influences for the prognosis of the patients.
3. The excellent prognosis was obtained in the group of patients whose lymphocytes count, total protein, A/G, and α2-globulin had returned within normal range postoperatively.
4. In respect of irradiation dose, the patients irradiated less than 3, 000 rads showed excellent cure rate. The group of patients who were treated with immunotherapy combined with radiotherapy had excellent prognosis.
5. There was no significant correlation between the histological type and prognosis of the patients.
6. The excellent prognosis was obtained in the patients with small round cell infiltration in their stromas. Those with fibrosis in their stromas had poor prognosis.抄録全体を表示PDF形式でダウンロード (2575K) -
小川 明, 山藤 勇, Eugene N. Myers1981 年 84 巻 8 号 p. 877-879
発行日: 1981/08/20
公開日: 2008/03/19
ジャーナル フリーTemporal bone histopathology of a case of congenital spondyloepiphyseal dysplasia was reported. The major findings were chronic suppurative otitis media, additional branch of the anterior crus of the stapes to the otic capsule, abnormal course of tensor tympani muscle tendon and crista neglecta in the horizontal canal ampulla. Cochlear structures could not be investigated because of a severe technical artifact.
Although this disease had been clinically described by others to cause a sensorineural deafness, middle ear abnormalities such as otitis media and a anomaly of stapes in this case also pointed out the possibility to cause a conductive deafness in this disease. So far as we know, this is the first temporal bone histopathological report of this disease and also the first case showing the crista neglecta in the horizontal canal ampulla.抄録全体を表示PDF形式でダウンロード (2335K) -
木村 雄介1981 年 84 巻 8 号 p. 880-889
発行日: 1981/08/20
公開日: 2008/03/19
ジャーナル フリーEar drum vibrations were studied in frogs by means of time-averaged holography. This method is useful for analysis of vibration and unique techniques which can record mode of vibration and vibration amplitude at a time. As the fringes represent iso-amplitude contours like those on geodesic maps, themode of vibration is clearly descenble at a glance. 17 ear drums from 17 frogs (Rana nigromaculata) were employed in the present experiments.
Results were as follows.
1) Vibration amplitude of the ear drum increased with SPL, but the vibration pattern remained substantially unchanged in each frequency.
2) In each frequency, the first fringes appeared at 80-90dB.
3) The complicated vibration pattern, showed two or more mounds, was recorded in this study. This pattern seemed to show the role of tympanic membrane as a buffering apparatus to decreased SPL.
4) Under 1 kHz, the ear drum showed rather a simple pattern. Above 4 kHz the pattern became more complicated, containing two or more mounds.
5) At about 2-3 kHz, proper vibration number was observed.抄録全体を表示PDF形式でダウンロード (2849K)
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