日本耳鼻咽喉科学会会報
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
80 巻, 4 号
選択された号の論文の9件中1~9を表示しています
  • 野田 寛, 都川 紀正, 栗田 健一, 松村 美枝子, 喜友 名千佳子, 赤松 隆, 松永 喜久
    1977 年 80 巻 4 号 p. 315-325
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
    In the series of investigation on the function of tonsils, the authors have reported in details on the individual redox substances in tonsilar tissue. In this study, the relationship between each component has been discussed. Each redox substance was measured as follows:glutathione and the thiol compound by the enzyme-spectrophotometrical method and the DTNB colorimetry; vitamin C by nitrophenyl hidrazine (DNP) method.
    The reduced glutathione and reduced vitamin C exhibited the positive correlation in palatine and pharyngeal tonsils. When the age of the patients was considered, the positive partial correlation was observed between these two substances. Positive correlation was also found in inflammatory stage or in chronic tonsillitis. Furthermore, the positive partial correlation existed with the degree of hypertrophy of palatine tonsils and the fluctuation of blood ASO titers, and the multiple correlation was found with ages in tubal tonsils.
    The oxidative glutathione and oxidative vitamin C revealed the negative correlation in hypertrophied tonsils, and in the non-inflammatory stage. The multiple correlation was found with ages particularly in palatine tonsils and in tubal tonsils, and the positive partial correlation was also shown with ages in tubal tonsils.
    When evaluating the ratio between oxidative and reduced glutathione and that of oxidative and reduced vitamin C, the multiple correlation with ages in palatine tonsils was indicated.
    No relations were found between the thiol compounds except glutathione and total vitamin C.
  • 毛利 学, 西尾 正寿, 毛利 純, 島津 薫, 赤根 賢治, 浅井 良三
    1977 年 80 巻 4 号 p. 326-333
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
    Clinical observations were performed on 100 patients who were treated for postoperative maxillary cyst during the seven year period from April, 1969 until March, 1976. The following results were obtained.
    1. The data on patients' sex, affected side, age of onset, onset-postoperative period relation, nasal findings and x-ray findings were similar to those of some other reports.
    2. Postoperative maxillary cyst was frequently observed after the Caldwell-Luc operation.
    3. The cyst developed more frequently when maxillary sinus was only operoted at the primary operation.
    4. In some patients, their teeth were involved in cysts. They should be called postoperative radicular cyst.
    5. Postoperative maxillary cyst is caused by the closure of the natural ostium and intranasal opening which was made at the primary operation in the inferior meatus.
    6. In preventing postoperative maxillary cyst, the following five should be kept in mind:1) complete resection of the sinus mucosa: 2) minimal operative bleeding: 3) selection of the operative method (Watsuji-Denker method is more preferable): 4) prevention of the closure of the natural ostium: and 5) treatment of the teeth exposed to the sinus. Among these, the prevention of the closure of the natural ostium is most important.
  • 荻野 敏
    1977 年 80 巻 4 号 p. 334-343
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
    The level of carcinoembryonic antigen (CEA) in the plasma was measured by the CEA assay system established by Hansen et al. in 91 patients, consisting of 73 patients with head and neck carcinomas, 7 with malignant lymphomas, 3 with Wegener's granulomatosis, and 8 with head and neck benign tumors. The plasma CEA level higher than 5.0 ng/ml was estimated positive and 15 of 28 (53%) laryngeal carcinoma patients, 8 of 13 (62%) maxillary carcinoma patients, and one of 8 (12%) nasopharyngeal carcinoma patients were positive. In total, 34 of 73 (47%) head and neck carcinoma patients had an abnormally elevated CEA level, whereas only one of 7 (14%) malignant lymphoma patients, and none of 8 patients who had benign tumors had positive CEA level. There was no significant difference in the plasma CEA level between the patients with adenocarcinoma and those with squamous cell carcinomas. The patients of the advanced stage who had metastasis of the cervical lymphonodi and/or the other organs showed significantly higher CEA level than those of the earlier stage. It was also found that the CEA titer dropped after successful therapies, but elevated again with the reccurrence of tumors. It seems that repeated CEA determination is a valuable means for assessment of the effect of the therapies and necessary in follow-up to tumors.
  • 佐藤 意生, 山口 良二
    1977 年 80 巻 4 号 p. 344-353
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
    This study was performed to apply an evoked EMG test to the larynx and to find out whether this test is valuable or not for diagnosis of patients with recurrent nerve palsy.
    Three types of evoked EMG wave were obtained from the ipsilateral intrinsic laryngeal muscles by giving electrical stimuli to three different sites. These were; from the cricothyroid by stimulation to the internal branch of the superior laryngeal nerve and from the thyroarytenoid by stimulation to the recurrent nerve and to the vagus nerve. A concentric needle electrode was used as a leading electrode. A pair of copper wire (diameter 80/μ) insulated except for a length of 5 mm at the tip was used as a stimulus electrode. Stimuli were rectangular current pulses of 1 msec duration and given at supramaximal level.
    In ten normal subjects, evoked wave induced by stimulation to the superior laryngeal nerve was polyphasic, while di-or triphasic by stimulation to the other nerves. The latency, duration and amplitude of evoked waves were examined. Threshold was not available because distance between the nerve and electrodes differed for case.
    Seven cases of recurrent nerve palsy were then examined. As a result, it was considered that the present test was valuable for the followings;
    1. Diagnosis of the site of lesion: the decision is easily made on whether the recurrent nerve alone or together with the superior laryngeal nerve is damaged, and on the damaged site along the recurrent laryngeal nerve in some cases.
    2. Inference of prognosis: Those cases showing no evoked wave may not recover completely. For the cases showing an evoked wave, information on prognosis can be obtained from the degree of changes in latency and evoked wave form.
    Information on reinnervation of the paralysed nerve: the evoked EMG test is able to revealthe condition of reinnervation as ordinary EMG test. Moreover, this test gives information on reinnervation at the earlier period than ordinary EMG test after the onset laryngeal nerve palsy.
  • YOSHINORI MINAMI, YOSHIFUMI MINAMI, AKIRA HORI
    1977 年 80 巻 4 号 p. 354-365
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
  • 笠井 英夫, 高原 滋夫
    1977 年 80 巻 4 号 p. 366-385
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
    One hundred and twenty four cases of middle ear malformation treated at Okayama University Hospital for the past 19 years were studied.
    1) About 40% of middle ear malformation with normal ear canal had a slight malformation of the auricle, such as projection of the anthelix. And their conductive deafness were due to stapes anomaly or fixation of the footplate.
    2) In malformation with a narrow ear canal 50% had maldeveloped mastoid cells, 70% the narrow tympanic cavity, 70% the malformed malleus and 80% the malformed incus. All of stapedes had abnormalities in shape and movement, and furthermore 20% of the malleuses and incudes was fused in one mass and 60% of the incudostapedial joints was dislocated because of maldevelopment of the long process of the incus.
    3) In complete atresia, half of the cases had immature mastoid process, 90% had small tympanic cavities including 4 ears with deficit cavity. Almost all of malleuses and incudes were malformed. 50% of the cases had either the fused malleus &incus or the separated incus &stapes. All of stapedes were malformed or fixed. Especially in atresia with immature mastoid process and very small tymyanic cavity, the course of facial nerve was extremely unusual, i. e., the horizontal portion was very low, or the vertical portion was short and displaced more anteriorly than usual. Even in the patients with complete atresia, their inner ear apparatus located in normal site, so it seemed that there was a longer distance between horizontal semicircular canal and facial nerve than usual. A high grade malformation of the middle ear was found in the atresia with congenital palsy of the abducens or facial nerve, the immature mastoid process or persistence of embryonal connective tissues in the small tympanic cavity frequently found in Treacher-Collins syndrome.
    4) Mastoid pneumatisation was very poor in 50% of abnormal ear canals.
    5) In hereditary malformation, the middle ear findings showed a close resemblance in each other from one genealogy.
    6) The grade of anomaly was in correlation with narrowness of the external ear canal.
    7) The findings of the middle ear in the malformed one seemed as if normal development of the middle ear was discontinued by some causes, i. e., hereditary defects, intra uterine fetal injuries, fetal position in utero.
  • 富山 紘彦
    1977 年 80 巻 4 号 p. 386-408
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
    The whole thickness of the epithelium of the human circumvallate papillae was divided tentatively into three portions from its superior surface, upper (UP), middle (MP) and lower portion (LP). Three transverse sections of circuvallate taste bud in each portion, totally nine sections, were observed and photographed with electron microscope. After constructing photomontages from nine sections magnified in about 2×104 and making contour pictures traced on three components of the taste bud, soma, nerve fiber and intercellular space, morphometrical observations were performed by curvimeter and planimeter.
    The number of somata examined was 255 at LP, 241 at MP and 292 at UP.
    The number of nerve fibers measured was 535 at LP, 272 at MP and 239 at UP.
    The results obtained from observations are as follows;
    1. The number of somata contacting with nerve fibers was 180 at LP, 162 at MP and 152 at UP.
    2. The average circumference length of the soma was 9.9 /1 at LP, 13.1 /1 at MP and 11.8 μ at UP.
    3. The average covering ratio of the soma with nerve fibers was 30.7% at LP, 23.7% at MP and 22.8% at UP.
    4. The average contact number of the soma with nerve fibers was 4.3 at LP, 3.3 at MP and 3.1 at UP.
    5. The average contact length of the soma with one nerve fiber was 0.8 μ at LP, 1.2 μ at MP and UP.
    6. The packing density of somata in the taste bud was 0.22/μ2 at LP, 0.11/μ2 at MP and 0.12/μ2 at UP.
    The quantitative observation of the human taste bud has not been reported up to date, hough many reports on the qualitative observation with electron microscope were seen. In this respect the quantitative morphometrical analysis employed in present study will be useful in the fields of physiology, histology and clinical medicine.
  • 菊田 晃
    1977 年 80 巻 4 号 p. 409-422
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
    Twenty normal adult rabbits with implanted electordes on the round window were used as experimental animals.
    These animals were divided into three groups in which they were exposed to 90, 100 and 100dB(SPL)of pure tones at 2kHz for two hours a day respectively.Coclear microphonics (CM)were measured immediately and twenty-two hours after each exposure.
    According to this experiment, five patterns of the daily change of CM were recognized;unaffected type, recovery type, recovery type, injury type and injury type.
    In most of cases, it was found that CM reduction immediately after exposure and CM recovery twenty-two hours after exposure became gradually unremarkable following the consecutive days of the experiment, and CM amplitude after twenty-two hours of recovery time after tone stimulation gradually increased day by day.This phenomenon was observed on 1 kHz, 2kHz and 4kHz test tones and in addition to this fact, the rate of CM reduction immediately after expoure was remarkable in order of 1 kHz, 2kHz and 4kHz.
    This phenomenon seemed to relate to habituation of the middle ear muscles because the experiment was done without anaesthesia and the rate of CM reduction immediately after exposure to low frequency test tone was remarkable.
  • 北村 武, 金子 敏郎
    1977 年 80 巻 4 号 p. 459-462
    発行日: 1977/04/20
    公開日: 2008/03/19
    ジャーナル フリー
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