日本耳鼻咽喉科学会会報
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
62 巻, 11 号
選択された号の論文の19件中1~19を表示しています
  • 倉井 寛子
    1959 年 62 巻 11 号 p. 2329-2337
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    Allergic reaction (Antigen-Antibody reaction) was observed in the ear labyrinth of rabbits, provocating Artus or Schwartzmann's phenomenon. As the tracer, Metal zine was combined to the both antigens with the care being taken not to disturb the activity of the antigens. Zinc tracer was detected as fine orange granules in the labyrinth tissue after the experiment by histochemical method. (E. Eegriwe) And these orange granules indicated the degree and, the site of the reaction.
    The results obtained were as follows:
    1) The clinical findings: Spontaneus nystagmus appeared in one third of the rabbits immediately after the injection. Postrotatory nystagmus decreased about in half of the cases. Positional nystagmus appeared in halft of eh cases rapidly, however in general, disappeared within a moment. Oto-lith reflex generally decreased after the injection.
    2) The histopathological findings : Edematous swellung and dilatation of blood vessels in the laby-rinth tissue were seen in a short time after the injection. Orange granules scattered especially alcng the wall of fine blood vessels. Allergic reaction occurred more rapidly and more severely on Vasc-ular stria and around the Saccus endolymphaticus, suggested by the mass of zinc granules. In Cortis organ, the tracer were deposited Deiter's Hensen's and Claudius's cells, a part of the support cell groups, however sensory epitherium did not show anyreaction. Sensory endorgans in Vestibular labyrinth showed generally the same changes as in the Cortis organ.
  • 河本 和友, 金子 豊
    1959 年 62 巻 11 号 p. 2338-2342
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    By Koelle's method for histochemical detection of Acetyl-Cholinesterase (ChE), we studied the localization of ChE in the cochlea, and following conclusions were made. In this method, copper sulfide deposit was demonstrated by the activity of ChE.
    1) A greater concentration of copper sulfide was seen in the inner haircells than in the outer haircells.
    2) The copper sulfide deposit was remarkable in the inner and outer haircells, specially at the base of the individual cells.
    3) The copper sulfide deposit was remarkable in Lamina perforata, where the nerve fibers appear from the bone
    4) Stria vascularis also showed minimal copper sulfide deposit.
  • 水谷 雅俊
    1959 年 62 巻 11 号 p. 2343-2353
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    The author attempted observations on 20 cases with upper jaw cancer clinically and histopath-ologically. Following results were obtained:
    1. Most patients were 40-60 years old. In the numbers of affected side there was no big differe-nce between right and left.
    2. All tumors were squamous cell carcinomas except one undifferenciated carcinoma.
    3. In the center parts of tumor the growth of carcinoma cells was rather expansive and in the peripheral parts it was infiltrative. Extent of the infiltration of carcinoma was different in the parts of tumor.
    4. The hone destructions were most frequently found at the orbital wall of maxillary sinus, and besides they were found at the ethomoidal sinus and the lateral wall, the anterior wall and the inferior wall of maxillary sinus. And after bone destruction by tumor, the formation of fibrous capsule against tumor was observed at the orbital, the posterior and the lateral wall of maxillary sinus.
    5. We could notice that in spite of large bone destraction of the orbital wall the infiltration of carcinoma cells into the orbita was prevented by the formation of fibrous capsule.
    6. In the most cases carcinoma cells did not infiltrate through the orbital wall, but they destro- yed the lateral wall of maxillary sinus and invaded the soft tissue and infiltrated into the orbita through the inferior orbital fissure.
  • 田中 弘
    1959 年 62 巻 11 号 p. 2354-2361
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    The author made histological and histochemical examinations on 113 tonsils obtained from 60 ppatients, and obtained following results.
    Glycogen and fat content, result of pyronin staining and localisation of the mast cells in the tissues were found to be in connection with the length of time after the acute inflammatory signs Ihad clinically subsided, PAS-stain, mucicarmin-stain, , amyloid degeneration and the hemosiderin deposit seemed not to be in close relation with the length of time after the inflammation.
  • 古内 一郎
    1959 年 62 巻 11 号 p. 2362-2374
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    A mycological examination was made on 132 outpatient of 13 loci in their upper respiratory tract and 173 strains of Candida were isolated in 41 cases (31.1%). A majority of these 41 cases consisted of the patients treated with Penicilline neburizer, the advanced-aged or cases of cancer, atrophic rhinitis and middle ear catarrh.
    As to the loci of isolation, Candida was isolated from the supratonsillar sossa and dental caries in 18.2 to 5% of the cases examined. These loci were considered to be the most common foci of infection of Candida together with the epipharynx of which a considerable number of colonies were usually proved by cultine.
    One hundred and seveny-three strains isolated were classified according to the Martin et al method. As a result, 120 strains were Candida albicans (70.5%). Moreover, Candida albicans was proved in each locus at the rate of 50 to 88.8%, showing the most predominant distribution in the upper respiratory tract.
    Mycological study revealed that 5 of 26 strains isolated were virulent and 4 of them were thermo-resistant for 5 minutes at 56°C.
    Immunological studies were also carried out on the 41 cases above mentioned and on the control group.
    The results obtained were as follows;
    1. Skin test was positive in not only the 41 cases but in control group at a cocentration of 0.1 to O.05γ.
    2. Precipitation reaction was positive in all cases examined at a concentration of 250γ/cc. At 125 γ/cc, however, only 5 out of the 41 cases showed positive result.
    3. Agglutination reaction was positive under 80-fold in all of the cases with exception of the 2 which showed positive result even at a concentration of 160-fold.
    4. Complement fixation reaction was negative in all of the cases.
    A few of the drugs generally used for external application in otolaryngological field of medicine were proved to have bacteriostatic effect for Candida in vitro.
  • 佐藤 正明
    1959 年 62 巻 11 号 p. 2375-2396
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    The author attempted a pathological study of the re-construction of the ossicular chain by using normal rabbits. Following results were obtained.
    1. One or two weeks after the operation the plastic flap became inflamed in acute, and gradually it was organized and had the tendency of healing. And about one monthlater it formed epithelium.
    2. The re-construction of the ossicular chain was usnful not for conductivechain, but for the support to tympanic membrane. Functionally it was useful only for columellization.
    3. Degeneration of the tympanic ossicles was caused not only by the inflammatory difficulation of circulation of blood, but also by bad nurtrition of bones themselves.
  • 横堀 国器
    1959 年 62 巻 11 号 p. 2397-2409
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    It has been thought that noise may be stressor, and stress in early stage of pregnancy is.considered as one of the etiologic factors of malformations at present. This experiment was performed in order to study the effect of noise given to female pregnant mice on their offsprings.
    White noise was given pregnant female mice of ddN strain, for 6 hours daily from the 11th day to 14th day of pregnancy, and the embryos were examined on the 18th day.
    The results obtained were as follows :
    (1) In the treated group, in which the noise of 90 phon was given, and in the control group, no malformations were observed. In the treated group, in which the noise of 100phon was given, one case of polydactylia was observed. And in the group, in which the noise of 110phon was given, 7 cases of malformation were observed. They were one case of cleft palate, one polydactylia, four encephalocele and one encephalocele with cleft face.
    Therefore, it became clear that noise induced malformations.
    (2) Even by the noise of 90 phon, the weight of embryos was decreased, and the louder noise, was given the more it was decreased.
    (3) Calculating blood eosinophils as stress index before and after noise stimulation, the louder noise was given the more eosinophils were decreased. While eosinophils were not so much -decreased still by 90 phon, they were decreased remarkably by the noise of 100phon.
    Therefore, it was found that noise stimulation played a role as stressor.
    It was infered as to teratogenic activity of noise that maternal pituitary-adrenocortical system responded to noise and affected embryos. Since teratogenic activity, growth inhibiting effect and decreasing effect against eosinophils of noise have been just found in mice, some undesirable influence upon embryos may appear also in humans if women are subjected to noise stimulation in early stage of pregnancy.
  • 追川 驍
    1959 年 62 巻 11 号 p. 2410-2417
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    Hearingloss due to allergic labyrinthitis was measured experimentally. 0.5cc of 2% egg white albumin solution was injected subcutaneously into the abdominal wall of guinea pigs every 4 days.These injections were repeated until the abdominal wall showed Arthus phenomenon. 0.2cc of 5% albumin solution was injected through the tympanic membrane of the animals into the middle ear cavity, when the animals were expected to show maximal allergy i.e. about 7 days after the appearance of IV degree of Arthus phenomenon. Marked allergic inflammation was histologically observed in the cochlea as well as in the middle ear 4 and 24 hours following the tympanal injection.
    Cochlear microphonics were measured by Tasaki's method in the animals treated as above mentioned. Allergic inflammation of the cochlea decreased the microphonics in a range of frequencies higher than 2000cycles. Individual variation of from almost normal to marked decreased level of the microphonics was observed.
  • 鳥山 寧二, 岡 正也, 吉浜 博太, 米沢 文子
    1959 年 62 巻 11 号 p. 2418-2420
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    Triple post operative cyst in a 62 years old man was reported. Left pansinectomy was done 25 years ago, and again he was operated for left post operative maxillar cyst 20 yearslater.
    Recently we found post operative cyst in left frontal sinus and ethmoidal cells.
    Only two cases of double post operative cyst have been reported in Japan, and these two cases were that of othmoidal cells and maxillar sinuses.
    This case of triple post operative cyst might be said to be the first reported case in Japan.
  • 特にレ線所見について
    横山 迪夫
    1959 年 62 巻 11 号 p. 2421-2439
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    1.In the last five years, chronic suppurative otitis media with cholesteatoma formation was seen in 188 cases (26.5%) out of total 709 cases which had been operated.
    2. In 2 cases, there was no perforation of the ear drum. In 10 cases, the ear drum was invisible because of the severe lesions of external auditory canal, and in 176 cases, perforation was found. The perforation was found in flaccid portion in 40 cases, in marginal portion in 15 cases, in central portion in 30 cases and 90 cases showed total defect of the ear drum.
    3. The clinical findings were coincident with operative findingo in 112 cases (59.5%) out of 188 cases.
    4. In 151 cases, 56 cases (37.0%) showed peculiar pictures of bone defect on X-ray, 68 cases (45.0%) were suspicious, and 27 cases (18.0%) were not clear.
    5. Mis-diagnosis was made on the X-ray films most commonly in the cases with small-sized localized cholesteatoma.
    6. In the X-ray diagnosis of these cases, we recognized that peculiar signs of bone defect as well as clear signs due to the enlargement of tympanic cavities were of great value.
    Part 2. Roentogenogram of the pneumatic cells of temporal bone in otitis media cholesteatomatica
    1. In 155 cases with cholesteatomas, no case belonged to Ist group of oneumatization, 5 cases (3.3%) belonged to IInd group, 14 cases (9.2%) to IIIrd group, 132 cases (87.5%) to IV th group. In general, the pneumatization was extremly poor, but we need to notice that 5 cases showed good pneumatization.
    2. There was no age-prevalence on the degree of pneumatization.
    3. In the X-ray diagnosis, the state of pneumatic cells is important, especially we must pay attention of the cases with good pneumatization.
    4. Concerning the cause of poor pneumatization, we would not agree to the opinion refers all the causes to congenital and aquired predisposition or constitution.
  • 高原 滋夫, 隅田 正二, 藤森 春樹, 長尾 暢三
    1959 年 62 巻 11 号 p. 2440-2445
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    During the two-year period from 1955 to 1957, the number of ears that we had been able todiagnose as clinical otosclerosis, amounted to 38 ears out of 21 cases examined in our department, and out of them only 15 ears received fenestration.In the postoperative hearing test of these 15 fenestrated ears, all of them showed improvement, although one case developed bony closure of the new fenestra, which was corrected by secondsurgery. Seven ears out of ten that we could follow up for more than one year after fenestration, restored the practical level of 30db in the average speech range. Ten ears out of 11 A-type earsrestored the level of 30db. In C-type ears, only one out of 4 ears restored a hearing improvement, reaching to the level of 30db.In average, the ears that had shown preoperative level of 53 db restored 24db, reaching to thelevel of 29db. Which is equal to the anticipated value obtained by Carhart's method preoperati-vely.Moreover, postoperative labyrinthitis was seen in 5 minimal type ears, 10 mild type and onemoderate type in the classification described by Shambaugh and Takahara. It is interesting to notethat minimal serous labyrinthitis was seen in A-type and also the most of A-type restored thepractical level of hearing. In the case with complete fixation of stapes, there was an averagehearing improvement of 25db after operation, while an average improvement was 17db in the caseswith incomplete fixation, showing that the cases with complete fixation were greatly improved bythe operation.
  • 吉田 重弘
    1959 年 62 巻 11 号 p. 2446-2449
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    Fatigue tests were done in the cases with otorhinolaryngological malignant tumors using urine.protein test, Hamasaki's and Donaggio-Sato's tests.
    1. The degrees of fatigue found were in the order, of malignant tumor patients, common otor-l hinolaryngological patients and normal subjects.
    2. In the patients with malignant tumors, the values of fatigue test were parallel to the tumorgrowth and the general condition of the patients as Ist, 2nd, 3rd stage in the table.
    3. The influence of the operation for the malignant tumors was more remarkable than that fornon-malignant otorhinolaryngological diseases. The recovery of the fatigue test value after theoperation for the malignant tumors was slower than that in the operations for non-malignantdiseases, being more than 6-7 days. In the cases with partial removal of tumor the fatigue test.value was higher and the recovery was much slower.
  • 吉田 重弘
    1959 年 62 巻 11 号 p. 2450-2454
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    The influence of otorhino laryngological operation on the human body was studrid using theurine protein test, Hatnasaki's and Donaggio-Sato's tests.
    The fatigue after the operation returned to the preoperative state within one week, and were parallel to the degree of bleeding and damage to the tissue.
    The highest fatigue value obtained in our experiments was in a case with the killian's radicaloperation for chronic frontal sinusitis and then in the order of chronic maxillary sinusitis conbinedwith ethomoiditis, radical mastoidectomy for chronic otitis media, tonsillectomy, submucous resection of septum and tonsil lo-adenotomy.
    It can be said that the measurement of fatigue value after operatios is valuable to find out the shortness in nutrition, in the determination of succeeding operation or discharge from the hospital.
  • 金井 美津, 大田 豊, 橋本 栄久代, 広沢 弘七郎
    1959 年 62 巻 11 号 p. 2455-2461
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    Electrocardiogram was taken in 197 cases, before and after the tonsillectomy togather with preoperative exercise test, of being truely pathologic S-T elevation in one case, flat T wave was Been in 2 cases, atrial extrasystole was seen in 3 cases, right bundle branch block or intraventricular conduction disturbance was seen in one case, and prolonged P-Q was seen in one case, the tolal being eleven cases (5.6%).
    Incidance of myocardial damage among those with chronic tonsillitis was not so high as previously had been reported by various authors.
    Therefore it should be emphasized that significance of electrocardiographic changes in tonsillar focal infections must not be overestimated, and careful interpretation should be made in reading electrocardiogram.
  • 田中 英治
    1959 年 62 巻 11 号 p. 2462-2484
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    We Performed the Histological Studies for the pur pose of prevention of fenestra that closeing by ossification, fallowing to the fenestration operation of labirinth.
    (1) On the normal rabbits, after 10th days the fenestra showed the States of fibrous inflammation, On the 30th days we found the periosteal assification is developping about 50th days, the fenestra is closeing by bone tissue and similarlyed bone tissue after 90th days, the fenestra showed ossific close due to the new bone.
    (2) These rabbits which were injected Cortison, showed faint fibrous reaction, after 30 th days the fenestra is open and after the 50th_??_60th days, we could not found remarkable Exchanges in ossification of new bone, Then treating of cortison locally, It has a rather preventive effect of claseing the fenestra due to new bone.
    (3) The rabbits which were loosed out the salivary gland, after the 30 th day there was no periosteal ossification and on the 50th_??_65th days the calcium deposition of fenestra was supressed and claseing mechanism of ossification was delayed.
    (4) The rabbits which were injected Parotine, showed the strong fibrous inflammation, associated with calcium deposition and fenestra claseing mechaniom due to newbone was promoting.
    (5) Useing of the faint skin-grafting valve, It was found that bone regeneration of fenestra is supressed.
  • 浜口 健, 出光 誠, 追川 驍, 岩崎 弘毅
    1959 年 62 巻 11 号 p. 2485-2488
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    The authors reported a case of Pemphigus Vulgaris which accompanied symptoms of skins a few months after initial effection of oral mucous membrans.
    This patient did well temporarily two months after the start of tha steroid hormon therapy, but last he dead unfortunately with return of this disease about 20 months after the start of this disease.
  • 第1篇 血液比重の変動について
    浜口 健
    1959 年 62 巻 11 号 p. 2489-2495
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    Observations were made of the changes of specific gravity in blood in the tonsillectomy, and the following results were obtained.
    1) After the injection of 0.5% Procain solution for the local anaesthesia, the specific gravity of whole blood (GB) and that of blood serum (Gs) were found to decrease in a similar process, although the decrease of (Gj) was less than that of (GB) in a slight extent.
    2) In order to detect a more detailed relation between the (GB) and the (Gs) reduction, an examination was made of the relative change between (GB-Gs) and (Gs- 1).
    The paradoxical phenomena was seen as a relationship between the two values during the period from the local injection to thirty minutes after the operation as well as at the point of two hours after the operation.
    3) From the above results it seems likely that the time inducing the shock reaction which has been clinically experienced after the tonsillectomy may be associated with the paradoxical phenomenon.
  • 第2篇 赤血球諸量の変動について
    浜口 健
    1959 年 62 巻 11 号 p. 2496-2504
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    1) Changes were induced of the property of red blood corpuscles in the tonsillectomy.
    2) Immediately after the injection for local anaesthesia an additional contraction of the corpuscles was observed for the macrocytosis, while untill 30 minutes after the operation there occured an additional expansion of the corpuscles for the microcytosis, and after two hours there was a contraction for the latter again.
    3) It seems very interesting that a very good coincidence was found between the time for expansion or contraction of the red blood corpuscles and that for inducing the shock in the tonsillectomy as well as for the paradoxical phenomenon, as in the cases of specific gravity described in the first part.
    4) Thus the tonsillectomy may be thought quantatively a light but qualitatively a heavy invasion to the organism.
  • 三島 則美
    1959 年 62 巻 11 号 p. 2505-2520
    発行日: 1959/11/20
    公開日: 2008/03/19
    ジャーナル フリー
    A X-ray tomographic study was made on the auditory organs of cadaveric and clinical persons, and the following results were obtained.
    1. The most preferable technic of photography was as follows; the objective person a lied down on abdomen, holding his or her objective ear on the X-ray film, turning his or her head a little to the opposite side, and at the same time the head was bowed 15 degrees downwards. The X-ray tube was traveled from the head towards the legs along the arxis of the body.
    2. To take the tomograph of the inner ear, 0.5cm should be added to the length of the external auditory canal which had been measured before the manipulation, as the depth of sectioning.
    3. In cases of acute and chronic otitis media, pathological changes in a definite layer were easily revealed in tomographic radiograms. Especially, the pattern of destruction of the temporal bone was clearly observed in the cases of otitis media cholesteatomatosa. In addition, differential diagnosis between the complete and the incomplete atresia of the external auditory canal was very sure by tomographic observation.
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