Thirty-five patients with cedar pollinosis were studied for clarifying the specificities of HLA antigens. Identification of HLA types was based on the result of the lymphocyte microcytotoxity test. There was a significantly high incidence of HLA-A10 and HLA-BW15 in cedar pollinosis.
The incidence of HLA-A10 was 11.7% in the control group and 68.6% (X2=49. 1, p<10-6,
Pc <10-5) in the patients, while that of HLA-BW 15 was 37. 1 % (X2= 12.8, p=5×10-', Pc=8 × 10-3) in the patients compared to 11.7% in the control.

抄録全体を表示

For the purpose of developing a new vestibular test for young children, a basic study of caloric eye deviation during sleep was performed in normal adults, infants and young children.
The same test was applied for infants and young children with hearing impairment.
The following results were obtained;
1) The caloric response during sleep was manifested as eye deviation to the stimulated side with water of 30-C and as deviation to the contra-lateral direction with water of 44-C.
The sleep condition of the stage 3 of Dement-Kleitman was estimated to be most suitable for the caloric test during sleep.
2) The means with standard deviations of the duration of eye deviation during sleep were 108. 5-18.7 sec with water of 30-C and 99. 6-12. 7 sec with water of 44-C in normal adult subjects; 70.5-26.4 sec with 30-C and 77.0-33, 4 sec with 44-C in infants of 4 to 18 months; 77. 1 -h 18. 8 see with 30-C and 70.6-32.8 sec with 44-C in children of 19 months to 3 year; 76. 6-20.6 sec with 30-C and 74.2-24.8 sec with 44-C in 4 to 7 year old children.
3) There was a positive correlation between the duration of eye deviation following caloric stimulation during sleep and that in wakeful state in the adult group (r=0.74 in the test using water of 30-C and 0.67 in the test using water of 44-C).
4) The rate of success of the test in infants and young children was in the range from 62. 5 % to 91.0%. The latency of the caloric response during sleep was longer and the duration of the response was shorter in children than in adults.
5) For those children with hearing impairment, all the subjects except one proved the test results to be within the normal range

抄録全体を表示

The purpose of the present report is to interpret human auditory evoked brain potentials recorded by the three-dimentional approach. Vectors of waves recorded by farfield technique were analysed. Simulation using a glass beaker and jelly was made on the assumption that physiological brain was a sphere of electrically homogeneous medium.
On the inner surface of a beaker, six electrodes were attached so that lines drawn between confronting electrodes formed three axis, X, Y and Z, which met at right angles with each in the middle of the beaker. Two resistance wires were positioned on X and Y axis respectively in the center of the structure. The beaker was filled with jelly dissolved in copper sulfate solution. Each electrode was connected to the wires by the jelly which was electrically homogenous but resistant medium.
This system implied that the resistance wires simulated the nervous pathway and the jelly tissues around it.
When a pulsed current was transmitted in the resistance wires, the electrical activity was recorded from the electrodes of three axis.
We studied the wave forms of three planes and then analysed their vectors on the basis of Lissajous' figure. The vector pointed to the direction of current flow. When one resistance wire was loaded, the waves recorded by the electrodes of three axis were all the same with regard to amplitude and phase. However, they were different when a pulsed current was conducted in two resistance wires at the same time. Yet, the electrical vectors of resistance were identical to the directions of Lissajous' figures of waves on three planes; frontal, horizontal and sagittal.
An experiment was performed also in a dog. Three electrodes were inserted into the brain with the aid of X-ray study, and a pulsed current was transmitted. The electrical activity was induced by surface electrodes placed on the head of the dog. Lissajous' figures of three waves had the same direction as the current flow of the intracerebral electrodes had.
It is reasonable to suppose that physiological brain is electrically homogenous, because the present experiment by using a dog brain revealed the similar results as the simulation in the jelly.
Therefore we examined auditory evoked brain potentials recorded on three axis in a healthy subject. Lissajous' figures showed the following facts.
N1 and N3 waves directed toward the opposite side to stimuli. Althogh the latter had a slight vertical component, they directed horizontaly. N5 waves was the largest vector toward a frontoparietal region. Vector of N2 and N4 waves were not completely confirmed. Thus, threedimentional analysis of evoked brain potentials will help us to understand thoroughly the nervous functions such as hearing.

抄録全体を表示

So-called mixed tumor in the otorhinolaryngological field is frequently found in the salivary gland, but that developed from the nasal septum is very rare.
This case was a 35-year-old male complairing of obstruction of the right nasal cavity and epistaxis. The right nasal cavity was filled with a tumor having a steel appeared from the nasal septum. The tumor was easily extirpated, and the size was 2.5 *2.3 *1.5 cm, and its weight was 3.5g. The histological picture showed diffuse proliferation of fibroblast-like cells, satellite cell-like cells, and the various kinds of cellular components, which characteristic for a mixed tumor of the salivary gland such as epithelial cell components forming the cell nests and many glandular cavities, those showing squamous cell metaplasia with a keratinized pearl and those with myxomatous change.
In Japan, 12 cases of this tumor have been reported so far and this case is the 13th.

抄録全体を表示