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83 巻, 11 号
選択された号の論文の9件中1～9を表示しています
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西田 裕明, 隈上 秀伯, 馬場 正明, 森内 晴美, 大沢 広秀1980 年 83 巻 11 号 p. 1435-1439
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリーWith the view of clarifying the mechanism of occurence of abnormally large amplitude of negative summating potentials (-SP) in clinical electrocochleography, electric responses of the cochlea were recorded from guinea pigs whose endolymphatic sac and duct were oblitered.
In reference to the waveform of AP, SP complex obtained by AVE recording using click stimuli, the animals were devided into three groups, i.e., (I) cases showing broadened waveform of AP, SP complex due to enhanced of the -SP, (II) cases showing -SP and normal waveform of AP, SP complex, and (III) cases showing +SP as in normal cases.
The waveform of AP, SP complex in Group I was very similar to that of clinical electrocochleographic findings in certain cases of pathological ears such as Meniere's disease and sudden sensorineural hearing loss. In all tested stimulus frequency functions the SP polarity recorded in scala vestibuli(SV), scala tympani(ST), and AVE SP and DIF SP proved to be predominantly negative in its trend. Histological investigation indicated the distension of endolymphatic compartment of the cochlea with displacement of Reissner's membarne, but -SP amplitudes were not always proportional to the degree of distension in these cases.
In this study it was postulated that the large amplitude of -SP would reveal the pathophysiological conditions in the cochlea, three of the scalae, i.e., SV, ST and scala media, all showed negative polarity in SP, leading to a negative SP of increased amplitude as a total sum or synthetic vector of SP components with the dominating negative polarity.抄録全体を表示PDF形式でダウンロード (1182K) -
第2編 皮膚反応の臨床的意義について鈴木 湛1980 年 83 巻 11 号 p. 1440-1453
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリー1) 病期分類(経過良好群,有腫瘍者群,治療直後群,進展群,末期群,対照群)に対し,多変量解析の手法を用いた結果,臨床的病期が一般臨床検査成績ならびに遅延型皮膚反応(PPD, Candida, SK•SD, Mumps,Varicella, PHA, DNCB)成績によって,ある程度裏付けられていることが分った.その際正準軸の2軸を検討し,第I軸は細胞性免疫に関するもの,第II軸は炎症に関するものと推論した.
2) 遅延型皮膚反応検査7種の平均評点で表わした成績が,頭頸部悪性腫瘍患者における日常一般臨床検査成績といかなる関連を有するかについて検討した.その結果,皮膚反応成績はリンパ球数,蛋白分画のような免疫機能に関係する項目以外に,貧血,体重減少,行動性弱化などのような全身衰弱に関係する項目に相関することが明らかとなった.
3) 遅延型皮膚反応と腫瘍の進展度との関係を検討すると,局所進展が進む程,また転移があるもの程,皮膚反応の平均評点が減少することを認めた.
4) 各患者の臨床病期が推移すると皮膚反応成績が,それに平行して変動するが,中にはかえって逆行する傾向を示す症例もあり,平均値として有意差は見られなかった.
5) 腫瘍の制御率(非再発率)を指標として,遅延型皮膚反応成績から予後予測の可能性を検討した,6ヵ月以上再発なく経過した経過良好時に検査した者を皮膚反応成績正常者群と反応不全群とに分け,その予後の差を見たが有意差は得られなかった.また治療中検査した者を皮膚反応成績正常者群と反応不全群に分け,その予後の差を見ると2年後の制御率において約10%の差が得られた.したがって遅延型皮膚反応検査のみによる予後予測は困難であるが,その参考資料とすることができる.抄録全体を表示PDF形式でダウンロード (1481K) -
小林 英人, 加藤 功, 小池 吉郎, 寺林 征1980 年 83 巻 11 号 p. 1454-1460
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリーThe distances between the right and left medial pterygoid plates were measured in 32 normal subjects and 12 patients with pituitary adenoma from both X-ray films of Waters' view and A-P tomograms, and compared with those of Americans reported by Lee. The results were as follows:
1) The distances between the right and left medial pterygoid plates in normal subjects were about 3.21±0.18cm (mean±S.D.). They were wider than those of Americans.
2) The distances in patients with acromegaly were not wider than those of normal subjects, however the measurements in patients with giantism were larger than those of normals.
3) The measurements of operative field in the transseptal transsphenoidal procedure to the hypophysis were about 2.0cm in diameter. They were about 1.0cm narrower than those determined from the X-ray films.抄録全体を表示PDF形式でダウンロード (1878K) -
本庄 巌, 松井 博史, 岡崎 伸博, 牛呂 公一1980 年 83 巻 11 号 p. 1461-1467
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリーIn order to study the detailed mechanism of the middle ear muscle reflex, especially the role of the tensor tympani muscle in the reflex, simultaneous recordings of both the middle ear impedance and the external ear pressure were performed in 100 normal ears. Acoustic stimulation to the contralateral ear and air-jet stimulation to the ispilateral eye which mainly produced the tensor reflex, were applied in this study. Each ten reflex waves was averaged by a medical computer. The results were as follows;
1) acoustic stimulation provoked inward movement of the ear drum in 52% of subjects, outward one in 25% and biphasic one in 23%. Thus, there was no consistent direction in the movement of the ear drum caused by the acoustic stimulation, suggesting participation of the tensor tympani muscle in the acoustic reflex.
2) air-jet stimulation to the eye produced inward displacement of the drum in 85%, which indicated marked contribution of the tensor muscle to this reflex. However, it was revealed that air-jet stimulation had a little effect upon impedance change of the drum.
3) latency of the reflex measured by external ear pressure was considerably shorter thant hat measured by impedance method.抄録全体を表示PDF形式でダウンロード (444K) -
鼻内形態整復術症例を中心に佐藤 敏彦, 臼井 信郎1980 年 83 巻 11 号 p. 1468-1473
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリーThe nasal resistance before and after reconstructive operation in 18 men with nasal obstruction was compared with that in 32 normal subjects. The nasal resistance was defined as difference between air way resistance through the nose and that through the mouth. The following findings were obtained:
1) In cases of nasal obstruction, the airway resistance through both nostrils was 3.5 times as high as that through mouth before the operation. It was improved to 2 times as high as the latter after the operatian.
2) In cases of nasal resistance was 2.5 times as high as the airway resistance through mouth before the operation. It was imprhved to 1 time as high as the latter after the operation.
3) In normal cases, the airway resistance thaough both nostrils was 2 times as high as that through mouth, and 1 time as high as the nasal resistance.抄録全体を表示PDF形式でダウンロード (387K) -
小野 寿之, 牧野 市郎, 星野 章範, 竹中 洋, 西村 秀夫, 豊田 弥八郎, 前川 平, 山口 恭平1980 年 83 巻 11 号 p. 1474-1481
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリーTwo cases of Fisher's Syndrome were reported and reviewed from the neuro-otological point of view.
Case 1: A 20-year-old man, 3 days after upper respiratory infection and diarrhea, complained of diplopia, ophthalmoplegia and ataxia. Neuro-otological examinations revealed dysdiadochokinesis, gaze nystagmus in both directions and direction-changing nystagmus to the uppermost ear. The righting reflex test, stepping test and rotation test were within normal limits. Eye movements were grossly limited but gradually improved afterwards. Optokinetic pattern test (OKP) and Eye tracking test (ETT) were almost normal. These results suggest that the lesion is located within the central nervous system, especially in the brain stem and cerebellum.
Case 2: A 20-year-old man, several days after upper respiratory infection and diarrhea, complained of general fatigue, numbness of the whole body, diplopia, ataxia, dysarthria and dysphagia.
Neuro-otological examination revealed ataxic gait, dysdiadochokinesis, gaze nystagmus in both directions. No positional and positioning nystagmus were seen. The results of OKP and ETT indicated the disturbance of the brain stem and cerebellum. These results suggest that the lesion was within the brain stem and cerebellum.
The exact site of the lesion of Fisher's Syndrome is still obscure, Several authors suggested the peripheral origin, where as the others claimed central nervous system involvement. The results of the neuro-otological examinations in our cases suggest involvement of the brain stem and cerebellum in Fisher's Syndrome.抄録全体を表示PDF形式でダウンロード (593K) -
大谷 巌, 大槻 好正, 相川 通, 竹中 正之, 尾股 丈夫, 大内 仁, 斎藤 武郎1980 年 83 巻 11 号 p. 1482-1490
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリーOtotoxicity and nephrotoxicity of aminoglycoside antibiotics (dibekacin, gentamicin and kanamycin) by rapid intravenous injection were histopathologically compared with those by intramuscular injection in 83 rabbits. The concentration of aminoglycoside antibiotics in serum and perilymph, after administration of two different routes was also comparatively assessed. The doses of antibiotics were 50mg/kg for dibekacin, 30mg/kg for gentamicin, and 100mg/kg for kanamycin. These antibiotics were administered for 30 days, and all animals were sacrificed 10 days after the last injection for histopathological studies.
The concentration of the antibiotics in serum and perilymph was determined through a single administration of two different routes in doses of 50mg/kg for dibekacin and 100mg/kg for kanamycin.
The results revealed that, although the peak serum level of antibiotics by the rapid intravenous injection was significantly much higher than that by the intramuscular injection, no differences in the transfer of antibiotics into perilymph and in degrees or patterns of inner ear damage or renal damage by antibiotics were seen between the two different routes. In other words, the results of the present study did not support the conventional idea that, the higher the peak blood levels of the aminoglycoside antibiotics, the more the damage in inner ear or kidney tends to take place.抄録全体を表示PDF形式でダウンロード (1479K) -
新川 敦, 坂井 真, 三宅 浩郷, 岩井 宏方1980 年 83 巻 11 号 p. 1491-1497
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリーWe developed a newly otological method of a panoramic tomography. The essential advantage of this method over the conventional radiographic techniques is that it is possible to radiograph both temporal bones and sinuses under identical conditions with one exposure.
The x-ray beam sourse has a 2mm. slit beam which moves horizontally from right to left or vice versa circularly. The traget film distance in this method is 65mm., the amplitude of the circular axis is 220 degrees and the image layer is approximately 20mm. thick in the desired resion. By moving the x-ray machine center backward 30 to 50mm. from the base line, both temporal bones and sinuses can be taken simultaneously. Radiation dose measurements using the phantom indicate 45.7mR to the left, 32.3mR to the right, those are approximately as the same as those of the conventional postero-anterior view.抄録全体を表示PDF形式でダウンロード (1701K) -
第1報 耳鼻咽喉科専門医に対するアンケートの結果報告小野 勇1980 年 83 巻 11 号 p. 1498-1502
発行日: 1980/11/20
公開日: 2008/03/19
ジャーナル フリーMass screening to detect early carcinomas of head and neck was rarely attempted previously. The rarity is due to rather low incidence of carcinomas of each site of head and neck region, and thus, efficiency of the screening is doubtful. But if there is effective method of first step screening which can be easily performed to decrease the population to be examined by ENT doctors, mass screening will be effective.
Carcinoma of the vocal cord is thought to be most suitable lesion for mass screening in head and neck cancers. From epidemiologic analysis of the patients with carcinoma of the vocal cord, patients who are older than 50 years with long-standing hoarseness and the habit of smoking more than twenty years, compose high risk population. These factors can be employed as first step screening. Mass screening limitted to these high risk population will not be difficult.
An enquete was attempted to obtain the opinions of ENT doctors about the mass screening for these high risk population.
Three hundreds and fifty five doctors answered to the enquete. Sixty-five percent of the doctors answered "mass screening should be done because the results of treatment will be better and the patients which can be controlled without sacrificing the larynx will considerably increase", but 25% of the doctors answered "mass screening is meaningless because the result of treatment for carcinoma of the vocal cord is satisfactory and efficiency of mass screening is doubtful because the incidence of carcinoma of the vocal cord is too low for mass screening."抄録全体を表示PDF形式でダウンロード (327K)
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