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Volume 107 (1972)
- Issue 4 Pages 303-
- Issue 3 Pages 203-
- Issue 2 Pages 105-
- Issue 1 Pages 1-
Volume 107, Issue 4
Displaying 1-12 of 12 articles from this issue
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TADAO ORII, RYOJI MINAMI, KAZUKO SUKEGAWA, SHIGEO SATO, SATOSHI TSUGAW ...1972 Volume 107 Issue 4 Pages 303-315
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSClinical, biochemical and electron microscopic studies on a patient of a new type of mucolipidosis are described. The patient is a 14-year-old Japanese boy who has coarse facies, dysostosis multiplex, neurologic deterioration, corneal clouding, macular cherry red spot, β-galactosidase deficiency, glycopeptiduria, and vacuolated cells in hepatic parenchyma, renal glomeruli, renal bone marrow and peripheral lymphocytes.View full abstractDownload PDF (3674K) -
MASAKUNI SUZUKI, MASAHIKO HIROI, KATSUYUKI TAKAHASHI1972 Volume 107 Issue 4 Pages 317-322
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSEffects of ethynodiol diacetate (SC 11800), which has been used for oral contraception as mini-pills, on the estrous cycle, mating behavior and pregnancy were investigated in comparison with those of progesterone, estradiol benzoate and testosterone propionate. When progesterone was administered in a dose of 0.02mg/day for 21 days, the estrous cycle remained almost unchanged, and all treated rats were pregnant soon after mating. When it was administered in higher dose, the female rat showed the vaginal smear of diestrous stage and became infertile as the natural ovulation was inhibited. When estradiol benzoate was administered in the same way, the vagina was swollen like hydrops and the vaginal smear showed estrous stage or quite different stage from it. In a dose of 1 μg/day, the copulation rate did not fall but the pregnancy rate fell markedly. But, in a dose of 10 or 100 μg/day, the copulation and pregnancy rate fell in all the rats treated. When testosterone propionate was administered in a dose of 1 μg/day, the estrous cycle was almost in order and all the rats treated copulated and conceived.View full abstractDownload PDF (348K) -
KAZUO NIGAWARA, YURIKO TERAYAMA, MATSUO TATEYAMA, TOSHIHARU SENO, YASU ...1972 Volume 107 Issue 4 Pages 323-336
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe present paper is concerned with studies on some problems in the measurement of plasma renin activity, i.e., inhibition of angiotensinase activity, some properties of renin activity, and concentration and purification of angiotensin from plasma. Renin was extracted from hog kidney by the method of Haas et al. (1965). Angiotensinase activity in the extract was well inhibited not only in neutral solution but also in acid solution with the aid of DFP. For the inactivation of plasma angiotensinase, addition of EDTA and DFP was employed rather than acid treatment. Addition of the agents inhibited the activity almost completely at a pH below 5.5. Although it appeared to us that hog renin activity was highest at pH 6, incubation for the determination of renin activity was carried out at pH 5.5, because angiotensinase was still active over pH 6. Angiotensin was semi-purified from plasma before the assay with a combination of n-butanol and water extraction, and ion exchange chromatography. The mean recovery of added angiotensin was 70 per cent in the purification procedure.View full abstractDownload PDF (729K) -
SHINJI TAKAHASHI, AKIRA TAKEUCHI1972 Volume 107 Issue 4 Pages 337-344
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe axial transverse tomograms are taken by means of the unit of the horizontal type. The range of tube rotation is 360° or 220°, and the direction of the central X-rays is craniocaudal or caudocranial for the patient laid supine on the tomographic table. The conclusion is that the tomogram of the neck taken caudocranially, that of the chest taken craniocaudally and that taken either caudocranially or craniocaudally by means of the above 220° rotation of the X-ray tube can be substituted for the tomogram taken by the standard technique of full rotation of 360°.View full abstractDownload PDF (1925K) -
TASUKU WATANABE1972 Volume 107 Issue 4 Pages 345-357
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSHistological and histochemical studies of 40 urinary stones were performed using polished specimens and decalcified serial sections with various stainings. In the stones containing oxalate, regularly arranged annual ring-like lamellae surrounded a formless central core, and crystals were present in interlamellar spaces in an orderly radial fashion. The stones not containing oxalate showed less organized structures, crystals being interspersed irregularly in non-crystalline substances which usually exhibited a reticular distribution. It was revealed histochemically that the matrix of stone as represented by these lamellae or reticula was composed mainly of acid mucosubstances, probably sulfated glycoproteins. Moreover, calcium stain followed by histochemical stainings for organic substances, on semi-decalcified specimens, indicated that these mucosubstances were distributed around cystals of calcium salt in such a manner as to combine the latter together. From these results it is inferred that, as was already proven for gallstones, mucosubstances participate in the formation of urinary stone as bridging agents for the crystalline components.View full abstractDownload PDF (2464K) -
RYOICHI SHIRACHI, NORIYOSHI SUKENO, TAKUSEI UMENAI, NAKAO ISHIDA1972 Volume 107 Issue 4 Pages 359-365
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSBiophysical study of Australia antigen (Au) was made with 5 specimens including 3 plasmas and 2 plasma pools which had been known to be Au carriers. A fraction which could be detected both by complement fixation test and by Ouchterlony double diffusion test was obtained with all of the specimens and this could be banded at a buoyant density of 1.21-1.23g/cm3 in CsCl. In addition, another fraction with a buoyant density of 1.28g/cm3 was recovered from one of the plasma pools. This fraction was detected, however, only by complement fixation test. Electron microscopic study of the latter fraction revealed small particles about 3-4 mμ in diameter, suggesting subunits of known Au antigen particles.View full abstractDownload PDF (775K) -
KOZO ISHIGURO1972 Volume 107 Issue 4 Pages 367-372
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe Determinations of specific gravity, hemoglobin content, hematocrit value and pantothenic acid content of blood samples of 199 females over 39 years of age living in a farm village of the north-eastern district of Japan were carried out in July, 1970. Regarding blood specific gravity, hemoglobin content and hematocrit value, no significant difference was observed among each mean value of the subjects grouped by age classes, though each mean value seemed to be somewhat low. However, the level of bound pantothenic acid in blood declined with age and this tendency was remarkable between subjects in the age classes of 40-49 years and 50-59 years, although free pantothenic acid content was found to be almost constant in each age class.View full abstractDownload PDF (294K) -
KOROKU HASHIMOTO, HISAKO KOKUBUN1972 Volume 107 Issue 4 Pages 373-380
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDrugs were administered to anesthetized dogs directly into the left renal artery perfused with animal's own blood at a constant pressure. A single injection of adenosine caused prompt renal vasoconstriction, while an infusion of adenosine caused initial vasoconstriction which recovered to the control level even though infusion was continued. The vasoconstriction caused by a single injection of adenosine was not only depressed but also reverted to vasodilation during infusion of adenosine in its concentration from 8×10-9 to 8×10-6g/ml in the perfused blood (self-inhibition), while norepinephrine-induced vasoconstriction was significantly enhanced in the concentration as low as 3×10-9g/ml of adenosine. The vasoconstriction caused by stimulation of renal periarterial nerve fibers was also significantly potentiated. These changes in responses disappeared promptly after interruption of adenosine infusion. Infusion of AMP acted similarly to adenosine but the effects were less. Infusion of ADP and ATP also depressed the effect of adenosine while the potentiation of the effect of norepinephrine was less during ADP infusion and absent during ATP infusion. Adenosine or AMP probably plays an important role in regulation of blood flow by modulating the adrenergic mechanism in the renal circulation.View full abstractDownload PDF (538K) -
SHIGETOSHI CHIBA, RAJKO IGIC, TAMIO NAKAJIMA1972 Volume 107 Issue 4 Pages 381-385
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe effects of tremorine and oxotremorine were investigated in seven vagotomized dogs, using direct perfusion technique of the S-A node under constant perfusion pressure of 100mm Hg. 1) Tremorine (30 μg to 1mg) and oxotremorine (0.003 to 0.03 μg) injected into the sinus node artery induced a negative chronotropic effect. This negative chronotropic effect was blocked by atropine, but was not influenced by tetrodotoxin and propranolol. 2) Higher doses of oxotremorine produced long-lasting atrial fibrillation. At doses larger than 0.3 μg, oxotremorine induced atrial fibrillation in all animals. The induction and maintenance of atrial fibrillation were blocked by atropine. The induction was also prevented by a large amount of tetrodotoxin and propranolol in some animals. A large dose of propranolol occasionally blocked the maintenance of atrial fibrillation.View full abstractDownload PDF (288K) -
Osteoporosis Prevalence and Nutritional Intake among the People in Farm, Fishing and Urban DistrictsSIGETOSI KAMIYAMA, SATORU KOBAYASHI, SHOICHI ABE, EIJI TAKAHASHI, EIKI ...1972 Volume 107 Issue 4 Pages 387-394
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDirect roentgenograms of dorso-ventral projection were examined on 1, 210 subjects in the sixth and seventh decades living in the different environments of farm, fishing and urban districts. The roentgenographic findings were classified into three grades according to osteoporotic changes, and the prevalence of osteoporotic changes was compared by χ2-tests among the districts. The prevalence was higher in the farm districts as compared to those in the fishing and urban districts. The examinees of the two districts, the farm and the fishing, were somatometrically measured of their spinal crookedness, and the results showed that the occurrence of crookedness was higher with concurrent high prevalence of osteoporosis in the farm village. Nutritional survey processed in all the five districts showed the causative difference of habitual food intake among the districts.View full abstractDownload PDF (462K) -
MASAHIKO OKUNI, KIMIE OKINAGA, KAZUO BABA1972 Volume 107 Issue 4 Pages 395-402
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSOne hundred and fifteen cases of acute infantile diarrhea, including 38 cases of breast feeding and 77 artificial feeding, were studied. 1) Reducing sugar was detected in 101 cases, 88% of the total cases. 2) In the breast-fed babies' stools of frequent diarrhea as well as stools containing much sugar tended to show high pH. 3) On the contrary, in the artificially fed babies stools of frequent diarrhea as well as stools containing much sugar tended to show low pH. 4) The oral administration of β-galactosidase preparation brought a good clinical effect on the acute infantile diarrhea of the artificially fed babies, but not satisfactory on that of the breast-fed babies. 5) In diarrheal stools of breast-fed babies, the majority of reducing sugars was found to be composed of oligosaccharide, and the stool contained lactose in very few amount and lactase was found to be of high activity. 6) Diarrheal stools of artificially fed babies, on the contrary, contained few oligosaccharide and much lactose and showed low lactase activity.View full abstractDownload PDF (389K) -
MASAFUMI SHIRAI, KEIICHI SASAKI, AKIRA RIKIMARU1972 Volume 107 Issue 4 Pages 403-404
Published: 1972
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSSparse catecholamine fluorescent fibers were found around the blood vessels and along the smooth muscle fibers within the muscular trabeculae of the human penis. Acetylcholinesterase-positive fibers were found rather abundantly in the muscular trabeculae of the cavernous body of the penis.View full abstractDownload PDF (642K)
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