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Volume 75 (1961 - 196･･･
- Issue 4 Pages 309-
- Issue 3 Pages 207-
- Issue 2 Pages 103-
- Issue 1 Pages 1-
Volume 75, Issue 2
Displaying 1-11 of 11 articles from this issue
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Erich Letterer1961 Volume 75 Issue 2 Pages 103-109
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
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Ryoji Kikuchi, Masako Chiba, Hiroshi Nakahama1961 Volume 75 Issue 2 Pages 110-121
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Hematocrit value, pH, chloride, sugar, inorganic phosphate and acid-soluble organic phosphorus in arterial blood of dogs were successively determined before and after the electrically induced convulsions and the following results were obtained.
2. The hematocrit value increased abruptly within 2-3 minutes and sustained the maximum value for more than 10 minutes, then returned towards normal at 30 minutes after the convulsion. 3. pH in the plasma decreased, attaining the minimum value at about 2-3 minutes and returned to normal by 60 minutes after the convulsion.
4. The concentration of chloride in the blood increased soon after the electroshock, and showing an increase in the Donnan's ratio, then returned to the initial value within 30-60 minutes following the electrical stimulation.
5. A marked rise in the blood sugar was found immediately after the convulsion and then slowly decreased, but it remained at a level higher than the initial one even 60 minutes after convulsions. This rise was little affected by the bilateral splanchnicotomy, but almost abolished after adrenalectomy.
6. The concentration of the plasma inorganic phosphate increased remarkably after the convulsion, showing the maximum value at about 30 minutes, then gradually diminished, but did not return to normal even at 60 minutes after the convulsion. On the other hand, cell inorganic phosphate showed a slight increase. No significant change in the concentration of acid-soluble organic phosphorus in cells was found.
7. The changes in the constituents of arterial blood by electric convulsions were discussed with regard to the results obtained from the experiments on the emotional excitement, hard exercise and hemorrhagic shock in man and animals.
The outline of this work was reported in the 28 th General Meeting of Japanese Physiological Association (1951).View full abstractDownload PDF (633K) -
Makoto Kurosaki1961 Volume 75 Issue 2 Pages 122-136
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Implantation of placentae of several stages of pregnancy beneath the skin near the crop of pigeons always caused considerable hyperemia, thickening and opacity of the mucous membrane.
2. Placental extract in saline caused negative crop reaction.
3. Placental extracts prepared by Bonsens and White's method, Li's method and Lyon's method always caused negative crop reaction.
4. The three extracts prepared by our method from full-term human placentae with the isoelectric point at pH 5.0, pH 5.8 and pH 6.0 caused always positive crop reaction, 1mg. of them being equivalent to 1/2, 1 and 2 pigeon units, respectively. Positive reaction also followed intramuscular injection of 20mg. of pH 5.0 and pH 5.9 fractions and 10mg. of pH 6.0 fraction.
5. Only the pH 5.8 fraction caused lactation upon injection into the lactiferous tubules of pseudo-pregnant rabbits.
6. When injected in post-puerperal rabbits with completely stopped lactation, all the fractions caused resumption of lactation.
7. When injected in puerperal women, all the fractions caused the increase of secreted milk over that in the non-treated controls. No side-effect of the administration was perceptible.
8. The chemical properties of the fractions were determined. The results pointed to the inference that it consisted in a prolactin-like protein.View full abstractDownload PDF (2392K) -
Kôzô Ishiguro1961 Volume 75 Issue 2 Pages 137-150
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1) A mass-survey of the pantothenic acid content in blood, the alkaline phosphatase activity and the total cholesterol content in serum was undertaken in an agrarian area with some 200 of the inhabitants over 30 years of age as subjects. The physiological age of the subjects was also estimated.
2) The mean pantothenic acid content in blood remained nearly stationary from 30 to 60 years but fell off gradually thereafter among males, while among females, the content went on declining with age, the mean value in the age classes of above 60 years showing significant drop at the level of significance below 5 per cent from that in the age classes of 30-39 and 40-49 years.
3) The activity of alkaline phosphatase in serum was found rising with advance of age above 50 years among both sexes, the mean value of above 60 years among females being significantly higher than that of 40-49 years among females.
4) The total cholesterol content in serum tended to increase with age, but not significant.
5) The pantothenic acid content among females was found correlated negatively with their calender age, physiological age and age estimated by outward looks, at the level of significance below 1, 5 and 1 per cent, respectively.
6) A significant negative correlation could be found between the activity of alkaline phosphatase in serum and the pantothenic acid content in blood, at the level of below 10 per cent.
7) No significant correlation was observed between the total cholesterol content in serum and the pantothenic acid content in blood.View full abstractDownload PDF (573K) -
Tatsuo Sato, Kaoru Yoshinaga, Yasuo Wada, Nozomu Ishida, Chuichi Itoh1961 Volume 75 Issue 2 Pages 151-157
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe urinary excretion of catecholamines and their metabolites was determined and the ratio among their values was calculated in normal and hypertensive subjects.
No significant difference in the excretion of methoxycatecholamines and vanillylmandelic acid was found between normal subjects and patients with essential hypertension.
The ratio of catecholamines/methoxycatecholamines/vanillylmandelic acid proved to be almost the same between them.
From these results, we discussed the problem of the pathogenesis of essential hypertension and could not support the hypothesis that an overactivity of sympatho-adrenal system or an abnormality in the enzymatic system of catecholamine inactivation is present in essential hypertension. In addition, we discussed the value of determination of catecholamines and their metabolites in making the diagnosis of pheochromocytoma.View full abstractDownload PDF (327K) -
Takao Saito, Mitsuo Sato, Kenichi Iwatsuki1961 Volume 75 Issue 2 Pages 158-167
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
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Toshio Honma1961 Volume 75 Issue 2 Pages 168-180
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe antibiotic susceptibility of 500 strains of staphylococcus aureus isolated from the patients with surgical suppurative diseases from December, 1957 to March, 1961 was studied.
The results obtained will be summarized as follows:
1) Only a few strains were inhibited by a low concentration of penicillin. On the contrary, the majority of the strains were inhibited by a low concentration of erythromycin. Distribution curves of susceptibility to streptomycin, chloramphenicol and tetracycline lay between those of penicillin and erythromycin.
The incidence of the resistant strains to five antibiotics was, in the order of frequency, 58.2 per cent to penicillin, 37.2 per cent to streptomycin, 18.8 per cent to tetracycline, 6.8 per cent to chloramphenicol and none to erythromycin.
Multiple resistant strains numbered 165, the majority of them being resistant to both penicillin and streptomycin.
2) Environmental and geographical influence on staphylococcal susceptibility was studied with three different groups of strains. With streptomycin and tetracyclin, there was a distinct difference between the strains isolated from hospitalized patients of our clinic and the strains isolated from the out-patients of suburban hospitals, the incidence of resistant strains being remarkably high in the former.
With chloramphenicol, a considerable number of the strains isolated from hospitalized patients of our clinic required a high concentration for inhibition, although not so remarkable as with streptomycin and tetracycline.
With penicillin and erythromycin, there was no remarkable difference in the susceptibility of staphylococci among the three groups.
3) Of the 133 strains isolated from the hospitalized patients of our clinic, the susceptibility of 50 strainss isolated between May, 1958 and January, 1959 and of 50 strains isolated between July, 1959 and March, 1961 were compared.
The penicillin resistant strains moderately increased, whereas with strep-tomycin and erythromycin, no significant changes were seen between the two groups. With chloramphenicol and tetracycline, no increase in the incidence of resistant strains was seen, but a decrease of sensitive strains and an increase of moderately resistant strains were seen in the lately isolated group.
4) As for the changes of the susceptibility of staphylococci after administration of a large amount of antibiotics, a decrease of sensitive strains and an increase of resistant strains were seen with every one of five antibiotics, the tendency being most remarkable with streptomycin.View full abstractDownload PDF (605K) -
Report I. The Effect by Administration of Small Dosis of Testosterone One Month after CastrationTadao Kanai1961 Volume 75 Issue 2 Pages 181-189
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSElectron microscopaic examination of the prostatic epithelium of castrated rats with or without subsequent administration of testosterone led to the following results.
1. In rats castrated and left untreated for a month, the epithelial cells were evidently atrophied, the electron density of the cytoplasm was lowered, the endoplasmic reticulum was faded out, and the mitochondria were reduced in size.
2. When such rats a month after castration were given per cutem 1-10 μg of testosterone solution in olive oil, no perceptible finding of recovery from the changes was obtained, but after 100 μg of it, the reappearance of endoplasmic reticulum was obvious, the mitochondria were re-enlarged and their internal structure was again definitely observable.View full abstractDownload PDF (2600K) -
Part I. Salivary Lysozyme Activity in AriboflavinosisHiromichi Oyake1961 Volume 75 Issue 2 Pages 190-196
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
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Part II. Lytic Action of Lysozyme upon Micrococcus Lysodeikticus Cultured with or without RiboflavinHiromichi Oyake1961 Volume 75 Issue 2 Pages 197-200
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
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Kenichi Iwatsuki, Tadanobu Katsurashima1961 Volume 75 Issue 2 Pages 201-205
Published: November 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSBuccal Varidase was administered to one hundred postoperative patients who either complained of difficult expectoration of viscid sputum or had such difficulty in previous surgery. The agent proved to be effective in facilitating expectoration in the majority of cases. No undesirable side-reactions were encountered in this group of patients. Buccal Varidase seemed to be a drug of choice in alleviating the complaints of the patients due to difficult expectoration and in reducing pulmonary complications in the postanesthetic period.View full abstractDownload PDF (767K)
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