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Volume 75 (1961 - 196･･･
- Issue 4 Pages 309-
- Issue 3 Pages 207-
- Issue 2 Pages 103-
- Issue 1 Pages 1-
Volume 75, Issue 1
Displaying 1-9 of 9 articles from this issue
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IX Structure of Shunted Blood Vessels in the Autopsied Cirrhotic LiverTakashi Nakamura, Shozo Nakamura, Toshimi Suzuki1961 Volume 75 Issue 1 Pages 1-9
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe intrahepatic blood vessels and intrahepatic shunted blood vessels were investigated in seven human autopsied cirrhotic livers by means of vascular acrylic resin casting, the injection of different colored gelatin through the vessels, and the histological examination of serial sections.
In all the cirrhotic livers, the changes were most prominent in the hepatic veins, which were compressed by the regenerated nodules of various sizes, became tortuous, and were reduced in number.
The portal vein was found less affected than the hepatic veins, but some of its branches were arranged in a basket-like fashion around the nodules.
The septums contained many blood vessels with broad lumen, which were considered to derive from surviving sinusoids. It is reasonable to presume that the porto-hepatic venous anastomoses develop from the pre-existing sinusoids included in the septums.
Anastomoses between the portal and hepatic veins were demonstrated in five of seven specimens. Grossly visible porto-hepatic venous anastomoses were less frequently observed than microscopic anastomoses measuring form 8 microns to 100 microns in diameter.
Histological studies of the serial sections revealed porto-hepatic venous anastomoses in two of six specimens. Three-dimensional figure of the portohepatic venous anastomosis was demonstrated in a reconstructed paraffin model.
Histological examinations of the livers of five rats with cirrhosis due to carbon tetrachloride, which were injected with different colored gelatin, revealed the flattening and tortuosity of the hepatic veins in all rats, and porto-hepatic venous anastomoses in four of five rats.View full abstractDownload PDF (3239K) -
Ting Fei Huang1961 Volume 75 Issue 1 Pages 10-16
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSNiacinamide in large doses (approximately 200mg/kg i. v.) increased the cardiac output of normal cats and of those after the ligation of the anterior descending branch of the left coronary artery. Sodium nicotinate in large doses (170mg/kg i. v.) had the same tendency, but less remarkable. These effects were compared with those of amyl nitrite and nitroglycerine in doses of 0.86-1.39mm3/kg and 0.32-0.52mg/kg i. v. respectively, which had ambiguous effects on the cardiac ouptut in both groups of cats. The effects of these drugs on the ECG findings are also briefly described.
This work was aided by grants (1959) from the National Council on Science Development of Republic of China. The author also would like to thank Dean H. Y. Wei for lending the ECG and to Prof. Y. Hosoya for his encouragement.View full abstractDownload PDF (1004K) -
Shungo Osato, Hajime Mori, Michio Morita1961 Volume 75 Issue 1 Pages 17-42
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1) In the present paper were studied changes in fine structure of Yoshida's ascites sarcoma cells as well as Ehrlich's ascites hepatoma cells by several anticancer remedies: Citral, Nitromin, Sarcomycin, Carcinophyllin, Chromomycin, Azan, PCMB, and Colchicine.
2) The localities of the points of attack upon tumor cells by these remedies are quite different. Nitromin causes changes unanimously of the fine structures of tumor cells. Azan and Sarcomycin come next to Nitromin in the order of effectiveness. Carcinophyllin and Chromomycin act moderately and they affect structures of cytoplasm rather than nucleus. Citral when acted mildly causes changes in nuclear membrane, nucleolus, chromatin substance in the nucleus. Change of endoplasmic reticulum is much more remarkable than that of mitochondria. PCMB damages mitochondria almost exclusively.
3) A potential co-operation of these two kinds of remedies, aldehydes and PCMB, is discussed.View full abstractDownload PDF (5645K) -
Kitsuya Iwama, Chosaburo Yamamoto1961 Volume 75 Issue 1 Pages 43-54
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe secondary discharge (SD) of negative polarity recorded from the posterior part of the convexity of the cortex was studied in cats and dogs under deep barbiturate anesthesia. The peripheral origin of sensory impulses was exclusively the sciatic nerve.
1. The first sign of the negative SD appeared 30 to 60 msee after the sciatic stimulation. The peak of the negativity was reached 100 to 130 msec after the stimulation, with a delay of 30 to 50 msec when compared with the peak of the positive SD of the sensorimotor area.
2. The negative SD was composed of the intrinsic and extrinsic components. The intrinsic component which in most of the cases was found superimposed upon the declining limb of the entire negative SD complex was affected by topically applied KCl, γ-aminobutyric acid and strychnine in about the same manner as was the primary evoked potential. The part of the negative wave which escaped from the actions of the chemicals was called the extrinsic component and supposed to come from an evoked potential in deep structures such as the anterior brain stem through physical spread.
3. When a microelectrode was thrust beneath the cortical surface, the negative SD's were recorded with augmented amplitude from the layers below a certain depth. The deep negative SD was also found to consist of the intrinsic and extrinsic components.
4. In association with the negative SD there was found facilitation of the primary evoked potential produced by stimulation of the specific thalamic projection nuclei. The maximal facilitation was obtained at the time intervals of 130 to 170 msec between sciatic and thalamic stimulations. This facilitation, at least a part of it, was supposed to depend upon enhanced excitability of the thalamus due to the sciatic stimulation.
We are indebted to Dr. Tomoaki Asano and Mr. Kozo Ohsaki for their kindly reading the manuscript. This study was supported by a grant from the Ministry of Education.View full abstractDownload PDF (4644K) -
Shosuke Seno1961 Volume 75 Issue 1 Pages 55-67
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (2815K) -
Takao Saito, Yoshibumi Kataoka, Kenichi Iwatsuki1961 Volume 75 Issue 1 Pages 68-70
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (123K) -
I. An Analysis of the Patterns of Activity of the Abdominal Wall Muscles in Non-pregnant Women and Pregnant WomenTorao Hatami1961 Volume 75 Issue 1 Pages 71-80
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe patterns of activity in various movements and resting discharge in supine and standing positions, in 51 pregnant women, in gravida in the 2nd-10th month of pregnancy, aged 20-37 were electromyographically investigated, with 11 non-pregnant women in parity 0-1, aged 21-46 for comparison. The results obtained from this experiment were as follows.
1. A tendency towards the involvement of all abdominal muscles in various movements was noticed with the progress of pregnancy, which tendency was not observed in the non-pregnant.
2. An increase in the muscle-activity was observed in the first half of pregnancy in various movements, while a decrease in the muscle-activity, especially in the obliques, was found in the latter half of pregnancy in various movements.
3. Takano has reported that muscle-action potentials for various movements are not found in the latter half of pregnancy using a needle electrode, although the present author could observe those in the latter half of pregnancy by using a surface electrode.View full abstractDownload PDF (491K) -
II. An Analysis of the Patterns of Activity of the Abdominal Wall Muscles in Nullipara or Primipara and MultiparaTorao Hatami1961 Volume 75 Issue 1 Pages 81-88
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe patterns of activity in various movements and resting discharge, both in supine and standing position, in 18 multipara, aged 36-72, were electromyo-graphically investigated, with those in 11 nullipara or primipara, aged 21-46, for comparison. The results obtained from this experiment were as follows:
1. A decrease in the muscle-activity in various movements was found ac-cording to an increase in number of parity.
2. The amplitude of the resting discharge in the internal obliques as an antigravity muscle in a standing position is raised according to an increase in parity. The amplitude of the resting discharge in the internal obliques over 100 μV was found in many multipara. This increase in the resting discharge from the internal obliques was particularly noticeable in over-7-times multipara.View full abstractDownload PDF (354K) -
Mutsuo Hirano1961 Volume 75 Issue 1 Pages 89-102
Published: October 25, 1961
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSWith the aim of studying the biosynthesis and the biological activity of estrogen, particularly of estriol, in the placenta, and besides obtaining some informations on the metabolism of estrogen in the fetus, the present author conducted some experiments. The results obtained were in summary as follows;
1. The placenta contains estriol in a higher concentration than estrone and estradiol-17β.
2. Estriol in urine and blood increases remarkably during pregnancy but decreased to nearly normal value in 72 hrs. after labor.
3. Estriol was found in higher concentration in the cord blood than in the maternal blood.
4. No difference in partitive concentration of estrogens was found in arterial and venous cord blood.
5. Estrone, estradiol-17β and estriol were all in high concentration in meconium and amniotic fluid.
6. In the placenta, estrone was found elaborated from cholesterol, progesterone and testosterone, but no conversion from sodium acetate to estrone could be proved.
7. Interconversion of estrone to estradiol-17β and vice versa could be observed in the placenta but no effect of gonadotrophin was apparent in accelerating interconversion of estrone and estradiol-17β, except that pregnant mare serum gonadotrophin showed a slight effect on conversion from estradiol-17β into strone.
8. When incubated in serum of pregnant women, however, conversion in the placenta from estrone to estradiol-17β was much more active than in Krebs-Ringer solution, and here conversion from estrone to estriol was also observed.
9. Estriol was weaker in catabolic activity than estrone and estradiol-17β.
10. Estriol acted depressant upon the oxygen consumption of the interbrain.
11. Estriol in large doses acted upon the uterine muscles, reduced the pressure in the cervical canal sometimes to zero and heightened the tonus of the vaginal wall.View full abstractDownload PDF (644K)
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