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Volume 109 (1973)
- Issue 4 Pages 309-
- Issue 3 Pages 205-
- Issue 2 Pages 97-
- Issue 1 Pages 1-
Volume 109, Issue 3
Displaying 1-9 of 9 articles from this issue
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KATSUHIRO NAKAMURA1973 Volume 109 Issue 3 Pages 205-221
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAn experimental study was made on the fine structure of RE-cells and lipid droplets in the adrenal cortex of albino rat. The results obtained were as follows: 1) Ultrastructure of lipid globules in the adrenocortical cells was well preserved by the use of polyethylene glycol for the procedure of dehydration and the finding was different with zoning of the cortex. 2) The capillary endothelia in the adrenal cortex showed only slight ability of phagocytosis and sequently should be excluded from RES. 3) Certain mesenchymal cells locating in the subendothelial and intercellular spaces of the parenchym showed distinct evidence of phagocytosis. These cells were named pericytes in this investigation. 4) The pericytes were frequently loaded with lipid droplets. The fine structure of them resembled that in the parenchymal cells of the zona fasciculata, but they were distinguished from each other by the different combination of fixation and embedment.View full abstractDownload PDF (7584K) -
SEISHO ITO, KEISHIRO KARITA, YASUO TSUKAHARA, KYOJI TASAKI1973 Volume 109 Issue 3 Pages 223-233
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe in vitro and in situ electroretinogram of squid (Todarodes pacificus Steenstrup) was investigated with microelectrodes. The electroretinogram recorded from the retinal surface was a sustained negative potential, but the response from the deeper layer was a positive potential (deep response), indicating that the receptor cell acts as an electric dipole. By moving a spot of light along a line passing over the microelectrode, it was shown that the deep response spread laterally from an illuminated area into surrounding unilluminated areas. From an experiment of selective adaptation by a polarized light, two sensitive planes were found in the squid retina, one responding maximally to a horizontally vibrating e-vector and the other being maximally sensitive to a vertical e-vector. The peaking wavelength in the spectral response curve of the electroretinogram is 480 mμ and agrees to absorption maximum of squid rhodopsin. Recording from freely swimming squid with an implanted electrode revealed the existence of marked oscillatory potential which occurred either spontaneously or responding to photic stimulation. This oscillation was considered to be attributed to summated impulses of the optic nerve fibers. Thus it was concluded that the axons of primary sensory cells convey impulses spontaneously to the central nervous system.View full abstractDownload PDF (551K) -
JUNICHI KADOWAKI, MAKOTO NIHIRA, TOORU NAKAO1973 Volume 109 Issue 3 Pages 235-244
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSChromosome studies were done on peripheral blood preparations from patients with three different viral infections, i.e., measles, chickenpox and mumps. Blood samples from subjects who were inoculated with live measles vaccine were also subjected to the study. In patients with viral infection, no significant evidence for either numerical or morphological changes of chromosomes was obtained, except in a few cases. There was also no chromosome damage nor depressed response to phytohemagglutinin in leukocytes from subjects who received immunization with attenuated measles vaccine. The nature of the discrepancy between the present result and the results of hitherto reported studies in regard to chromosomal aberrations in viral infection was discussed.View full abstractDownload PDF (465K) -
OTOTAKA HIGASHI, YOKO KIKUCHI, KIMIICHI KONNO1973 Volume 109 Issue 3 Pages 245-250
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn contrast to the adenosine diphosphate (ADP)-induced platelet aggregation, the hydrogen peroxide (H2O2)-induced platelet aggregation could be inhibited by either potassium cyanide or sodium azide or antimycin or oligomycin alone, suggesting that aerobic metabolism of glucose is essential to maintain a complete ability in aggregation of human platelets.View full abstractDownload PDF (269K) -
EIETSU OUCHI, KIYOMI MIURA, SHOICHI YAMAGATA1973 Volume 109 Issue 3 Pages 251-259
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSTritiated Congo red was prepared by the gas exposure method. Analytical results obtained by thin layer chromatography and spectrophotometry indicated that the radioactive Congo red thus prepared had the same properties as the original material. The incorporation of tritiated Congo red into the RES tissues of Donryu rats was studied after intravenous injection by autoradiography and liquid scintillation counter. It was found that Congo red was taken up by Kupffer's stellate cells specifically. The uptake of stellate cells reached a maximum level at the end of 24 hours after injection. However, silver grains were not found in any of the RES cells of other organs at this time. Radioactivity was detected in various tissues. The highest level was found in kidney and followed by liver, lung, spleen, heart and large intestine in decreasing order.View full abstractDownload PDF (1791K) -
HIKARU ISHIDA1973 Volume 109 Issue 3 Pages 261-280
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe fine structure, differentiation and destination of embryonal granular cells of the chick cerebellum were studied by means of electron microscopy. The embryonal granular layer (EGL) was divided into the external layer, the internal layer, and the transitional zone between the internal and molecular layers. Cells of the external layer showed active mitosis and appeared most primitive in shape and in development of cell organellae. Cells of the internal layer possessed long bipolar cytoplasmic processes parallel to the cerebellar surface as viewed in the frontal section. These processes were of two types: In some cells they were electron dense, with microtubules; in others, they were electron light, with microfilaments, and have some deeply folded rumples running longitudinally along the processes. In the transitional zone, the former cells (dense processes) obtained the characteristics of nerve cells, with developed rER and immature synapses; the latter cells (clear processes) the characteristics of glia cells. Those external layer cells with cytoplasmic end-feet in contact with the pia limiting membrane developed into Bergmann's astrocytes. Few degenerated cells were observed in the EGL, their number being far less than that of mitotic cells. Dense cored vesicles about 1, 000 Å in diameter were observed in the EGL, but their nature is not known in the present study.View full abstractDownload PDF (10537K) -
TOKIHISA KIMURA, RYUZO YOKOYAMA1973 Volume 109 Issue 3 Pages 281-296
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSBoth urine flow rate and urine electrical conductivity were recorded continuously in hydrated alcohol-anesthetized rats, and the patterns of changes in these two induced by intravenous injection of ADH were compared. Although ADH-induced changes in urine flow rate and conductivity were reciprocally related, significant deviation from a simple reciprocal relation was found when a relatively high dose of ADH was given. Dose-response curves as obtained by using the maximum magnitude or the time-integral of the response as the index of the response revealed that the urine-flow method has higher sensitivity to ADH in a relatively low dose range, whereas the conductivity method is superior for the assay of relatively high dose of ADH. Saluresis induced by NaCl-loading or by administration of Furosemide produced parallel increases in both urine flow and conductivity, while a reduction of blood pressure caused parallel decreases. Asphyxia and pentobarbital sodium produced ADH-like (reciprocal type) pattern of changes, but these changes were interpreted as the results of a liberation of endogenous ADH. Diuretic effect of a low dose of ADH, saluretic effect of a moderate dose of ADH, and vascular effect of a high dose of ADH were characterized by the dual recording of urine flow rate and conductivity. It is concluded that the dual reocrding of urine flow rate and conductivity is recommendable for the assay of ADH of a wide range of dose since the renal effect of ADH is of composite nature, and the single recording of either of these urinary factors cannot characterize the ADH action.View full abstractDownload PDF (832K) -
SHIGERU ARAI1973 Volume 109 Issue 3 Pages 297-306
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe renal arteries of five patients with hypertension accompanied by radiologically demonstrable stenosis of the renal arteries were submitted to histological and histometrical examinations. Cases of arteriosclerotic stenosis of the renal artery were not included in the present study. Fibromuscular dysplasias were found in both hilar renal arteries and intrarenal ones, the latter of which caused poststenotic oligemia and provoked hypertension. Subadventitial fibroplasia was attributed to subadventitial hematoma due to medial weakness. Vascular fibroplasia was occasionally found in renal arterioles. In clinically confirmed ischemic area of the kidney there was no hypertensive arterial changes. The arterial muscular coat was found attenuated in such an area.View full abstractDownload PDF (3325K) -
SHUNZO CHIBA, TATEKI FUJIWARA, HIROSHI SHIONO, TOORU NAKAO1973 Volume 109 Issue 3 Pages 307-308
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSNinety-eight serum specimens obtained from 53 cases of hepatitis in children and 11 specimens from 10 cases of biliary atresia were tested for Australia (Au) antigen by radioimmunoassay (RIA). Au antigen was detected in 3 out of 10 cases of post-transfusion hepatitis (30%), in 14 out of 18 cases of viral hepatitis (78%) without known parenteral exposure to blood or blood products and in 2 out of 2 cases of chornic hepatitis (100%). In contrast to them, antigen was detected in none of 23 cases of neonatal hepatitis and 10 cases of biliary atresia.View full abstractDownload PDF (99K)
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