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Volume 81 (1963 - 196･･･
- Issue 4 Pages 297-
- Issue 3 Pages 207-
- Issue 2 Pages 107-
- Issue 1 Pages 1-
Volume 81, Issue 3
Displaying 1-9 of 9 articles from this issue
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Satoshi Sato, Mitsuaki Tateyama, Chojiro Sasamori, Shigeru Kobayashi, ...1963 Volume 81 Issue 3 Pages 207-214
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSOn 25 cases of hypertension and 16 cases of postapoplectic patients with hypertension the cerebral carbohydrate metabolism was estimated, simultaneously with the cerebral hemodynamics, using Kety's N2O method. The cerebral glucose consumption was generally smaller in these patients than that of healthy subjects. It was found not to stand in such a close relationship with cerebral oxygen consumption as it was the case in healthy subjects. It depends on the glucose content in arterial blood to some extent. Some disturbances are presumed in the blood glucose transfer into the brain tissue. No significant difference was detected between the hypertensive and the postapoplectic subjects in respect of the cerebral glucose consumption. An increased lactic acid forma-tion was presumed in the brain of these patients, especially in the hypertensive patients: The amount of lactic acid carried out of the brain was in many cases too large to be explained by the decrease in oxidized part of blood glucose owing to the reduced oxygen supply.View full abstractDownload PDF (305K) -
Satoshi Sato, Mitsuaki Tateyama, Chojiro Sasamorl, Shigeru Kobayashi, ...1963 Volume 81 Issue 3 Pages 215-221
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSOn 19 healthy subjects distributed in almost all age ranges, the glucose, the pyruvic acid and the lactic acid contents were measured in the blood samples taken from the internal jugular vein and the femoral artery, simultaneously with the cerebral hemodynamics by N2O method, to determine the amount of metabolized carbohydrates in unit weight of brain tissue. The cerebral glucose consumption (CMRgl) was found in a close relationship with CMRO2, suggest-ing that the blood glucose is the most important source of energy for the brain. Cerebral arteriovenous differences of glucose and cerebral blood flow were in a negative correlation, indicating the constancy of glucose supply as energy source. Pyruvic acid and lactic acid were estimated to be carried out from the brain in almost all cases, but the correlation between the outflow of these acids and the cerebral oxygen consumption was obscure. The mean value of cerebral glucose consumption was almost equal to the sum of mean values of the cerebral oxyda-tion of glucose and the amounts of acids transferred out of the brain. Hence, an equilibrium in carbohydrate metabolism of therbrain of healthy persons was .elucidated. In aged subjects, the derangement of carbohydrate metabolism is evident with a well balanced equilibrium on a lower level, presumably as a physiological senile phenomenon.
These findings and presumptions should be evaluated in future by more accurate methods, which enable us to analyze obtained values more exactly. From the present stand-point, we should be satisfied with the present summaries.View full abstractDownload PDF (298K) -
Jeunichiro Nagasawa1963 Volume 81 Issue 3 Pages 222-237
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSSodium and potassium movements in smooth muscle of guinea-pig taenia coli were measured with radioactive isotopes. In low temperature (20°C and 2°C), uptake of 42K and loss of 24Na were reduced considerably, but loss of 42K and uptake of 24Na were not so much affected. Adrenaline (1×10-5g/ml) had no significant effect upon the movement of 24Na, though it had suppressed the spontaneous contraction completely. Acetylcholine, adrenaline, histamine and serotonin also increased the efflux of 42K.View full abstractDownload PDF (757K) -
Hisao Suzuki, Yasuo Tukahara1963 Volume 81 Issue 3 Pages 238-245
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA thermoelectric recorder using a tiny thermistor bead heated by an electric current of suitable strength is described. When immersed in a flowing fluid, the recorder is very sensitive to flow changes, and the rate of response is much higher than that of usual recorder using a heated thermocouple. A needle-type element of this device having the thermistor bead on its tip is small enough to be inserted deep into the brain without any serious injury of the tissue. Its usefulness for measuring instantaneous changes of local blood flow in the brain tissue has been confirmed by several experiments.View full abstractDownload PDF (377K) -
Kaoru Yoshinaga, Keishi Abe, Isao Miwa, Mitsuyasu Aida, Masaru Maebash ...1963 Volume 81 Issue 3 Pages 246-253
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAn assay method of urinary kinin was described. It consists of extraction of the peptide into n-butanol, re-extraction back to a weak acid solution, concentration under reduced pressure, neutralization and bioassay on the isolated guinea-pig ileum.
The method was fairly simple and can be carried out without difficulty. The recoveries and the accuracy proved satisfactory. The method is also specific for the kinin in urine.
Ten to thirty micrograms of kinin were excreted daily by healthy persons.View full abstractDownload PDF (851K) -
Masataka Kato1963 Volume 81 Issue 3 Pages 254-255
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (52K) -
Mizu Kojima, Kazuko Kikuta, Atsushi Dazai1963 Volume 81 Issue 3 Pages 256-266
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAmong 249 cases of leukemia examined, there were 88 cases (35.3%) which were associated with tumor formation. These tumors occurred singly or multiply, in various kinds of leukemias and favorably in the kidney, mediastinum, skin and periosteum. Concerning the frequency of tumor formation, chloroleukemia had the highest rate, followed by monocytic leukemia, while myeloid leukemia showed a considerably lower rate. There was no difference in the frequency of tumor formation between acute and chronic leukemia, nor in relation to the number of mitotic figures of the leukemic cells. Consequently the tumor forming leukemia is hardly regarded as the more malignant form of leukemia, but is to be considered nothing but one type of neoplastic growth of blood cells. Finally it is considered that the condition of the host seems to be significant as the factor, determining tumor formation as well as the sort and character of leukemic cells.View full abstractDownload PDF (539K) -
Masao Muto, Susumu Majima, Koichi Yoshida, Katsumi Karube, Teiichi Tes ...1963 Volume 81 Issue 3 Pages 267-278
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (540K) -
Masao Muto, Susumu Majima, Koichi Yoshida, Katsumi Karube, Teiichi Tes ...1963 Volume 81 Issue 3 Pages 279-296
Published: December 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn 1037 cases of stomach cancer who survived subtotal gastrectomy at the authors' department, the relations between various pathologic as well as clinical aspects of stomach cancer and the end-results were analyzed. Of the factors studied, the extent of the extragastric spread of carcinoma was the most closely related to the longevity of patients, while the nature of the primary tumor less faithfully indicated the prognosis. The authors' P. C. classification, a grading for the extent of peritoneal dissemination, was proved to be a good measure of the prognosis and it was emphasized that the omenta should be extensively excised on the radical surgery for stomach cancer.View full abstractDownload PDF (767K)
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