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Volume 98 (1969)
- Issue 4 Pages 303-
- Issue 3 Pages 215-
- Issue 2 Pages 107-
- Issue 1 Pages 1-
Volume 98, Issue 1
Displaying 1-10 of 10 articles from this issue
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Hiroshi Shiono1969 Volume 98 Issue 1 Pages 1-6
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDermatoglyphic study of 20 patients with XXYY Klinefelter's syndrome, including 2 cases of our own, revealed that the simian lines were not so useful, at least in the Japanese population, in distinguishing the XXYY sew chromosomal constitution from the other types of the Klinefelter's syndrome.View full abstractDownload PDF (332K) -
Minoru Karahashi1969 Volume 98 Issue 1 Pages 7-12
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIsocitric dehydrogenase (ICD) activity of the cerebrospinal fluid was measured on 88 children with various disorders of the central nervous system and on 19 children with non-neurologic diseases, the latter serving as controls.
The cerebrospinal fluid ICD activity ranged from 0.9 to 7.7 units with a mean of 4.2±2.1 units in the control series, and was elevated in 7 out of 33 patients with cerebral palsy, in 2 out of 14 with grand mat epilepsy, in one each of cases with viral infection of the central nervous system, cerebrovascular disorder or miscellaneous neurologic disorders, and in none of cases with metabolic errors or infantile spams.View full abstractDownload PDF (305K) -
Hiroshi Hiragami, Shiro Nagaoka, Yoshimasa Yabe, Takashi Sugiyama, Yut ...1969 Volume 98 Issue 1 Pages 13-20
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA 26-year-old male with Marfan's syndrome complicated by renovascular hypertension was reported. Stenosis of the main renal artery among the left multiple renal arteries was proved. In the present case, a high incidence in cerebrovascular disturbance was found on the paternal side. The patient expired on account of malignant nephrosclerosis following an attack of cerebral apoplexy. The causative relationship between Marfan's syndrome and reno-vascular hypertension was discussed.View full abstractDownload PDF (3400K) -
Yasuhiko Sasaki, Tsuneo Takahashi, Norio Suwa1969 Volume 98 Issue 1 Pages 21-32
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe inner medulla of rabbit's kidney was examined for the total internal circumferences of Henle's thin segments and collecting tubules at a given medullary height. The results could be approximated by H(x)=168 (e0.60x-1) for Henle's thin segments and A(x)=114 (e0.39x-1) for the collecting tubules. In the expressions x is a distance in mm taken along a medullary ray from the medullary apex to a certain point of the inner medulla, and H(x) and A(x) give the total internal circumferences in mm of Henle's thin segments and collecting tubules respectively on a curved surface defined by x.As indicated by different exponents in H(x) and A(x), quantitative predominance of Henle's thin segments over collecting tubules toward the external border of the inner medulla was demonstrated. This was also an expression that in the pile of Henle's loops short loops were overwhelm-ingly larger in number than long ones.
On the assumption that Henle's loops supply sodium to the interstitial tissue and produce a gradient of sodium concentration rising toward the medullary apex, the structural principle of the inner medulla would counteract the effect. Our histometrical analysis did not consequently favor the counter-current hypo-thesis. The above equations are to be used in our forthcoming mathematical analysis on the mechanism of urinary concentration.View full abstractDownload PDF (2544K) -
Yasuhiko Sasaki, Norio Suwa1969 Volume 98 Issue 1 Pages 33-63
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe function of the inner medulla was analyzed on mathematical models with parameters of medullary structure. Three different theoretical assumptions were made on Henle's loops. The loops were regarded as an exchanger system of dif-fusion type, a counter-current multiplier system or a transport system with active sodium transport only on the ascending limb. The collecting tubule was treated as having active sodium transport and giving water to the interstitial tissue.
When Henle's loops were treated as a sodium-depriving system, the structure of the inner medulla characterized by quantitative predominance of Henle's loops over the collecting tubule toward the outer medulla acted synergetically to raise interstitial sodium concentration toward the medullary apex. In regard to the effect, the assumption of Henle's loops as a sodium-supplying system was conflicting with the medullary structure. The counter-current multiplier hypothesis of Henle's loops was not supported, because it presupposed the loops as a sodium-supplying system. Conversely, the model with Henle's loops as an exchanger system of diffusion type was found to be the most reasonable simulation of the inner medulla. A hypothesis of intramedullary sodium circulation involving both outer and inner medullas was proposed for the mechanism of water absorp-tion from the collecting tubule or urinary concentration.View full abstractDownload PDF (2022K) -
Toshio Sato, Kenji Koyama, Kenichi Watanabe, Shunichi Kimura1969 Volume 98 Issue 1 Pages 65-74
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe changes of portal pressure were studied in adult mongrel dogs, while sple-nic blood flow was let increase in five steps from 0 to 350 ml/min. When intrahepatic portal circulation was left intact, there was no appreciable change in the portal pressure concomitant with changes of splenic blood flow, but in dogs with obstruc-tion of intrahepatic portal branches by silica particles, increase in splenie blood flow caused a marked elevation of the portal pressure, The role of the increase in splenic blood flow and the obstruction of intrahepatic portal branches in the pathogenesis of portal hypertension in idiopathic splenomegaly was discussed.View full abstractDownload PDF (1251K) -
Katsuhisa Sato1969 Volume 98 Issue 1 Pages 75-79
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe following results were obtained by histochemical studies of N-acetyl-β-galactosaminidase (β-GA) and N-acetyl-β-glucosaminidase (β-GL) in the human ovary.
1) The distribution of β-GA was quite similar to that of P-GL, but the activity of βGA was lower than that of β-GL
2) Although no activity of β-GA or β-GL could be detected in primary follicles, some activity appeared in the theca interna layer of the developing follicles, and the activity increased as the follicles enlarged. However, no activity was found in the granulosa layer.
3) The activity of β-GA and β-GL was extremely intense in the granulosa lutein cell layer in the florid stage of the menstrual corpus luteum but was even more intense in the corpus luteum in the initial stage of pregnancy. The activity was lower in the theca lutein cell layer.View full abstractDownload PDF (768K) -
Tetsuo Maki, Naoshi Nakamura1969 Volume 98 Issue 1 Pages 81-86
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThin serial sections of calcium bilirubina.te gallstones were prepared by Nakamura's resin-reinforcing method. They were submitted to histochemical stainings and the result was compared with that obtained with non-stained control sections.
When a section was observed under high magnification, granular particles of calcium bilirubinate were seen deposited in all areas of the section, and the area where these particles accumulated densely constituted a lamellar structure. Histo-chemically, calcium bilirubinate gallstones contained acid mucopolysaccharides including sulfated polysaccharides, and it appeared that the substances were diffusely distributed and connected calcium bilirubinate particles with one another. The present report stresses an important role of mucopolysaccharides in the forma-tion of calcium bilirubinate gallstones as in the case of calcium carbonate gallstones.View full abstractDownload PDF (1758K) -
Toyoaki Akino1969 Volume 98 Issue 1 Pages 87-97
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe sphingolipids, i.e., ceramide, cerebroside, sulfatide, sphingomyelin, and ganglioside were isolated in semiquantitative yield from the pig brain by combina-tion of column and thin-layer chromatography and identified by thin-layer chromatography, infrared spectroscopy and quantitative analyses. The sphingosine base and fatty acid compositions of each sphingolipid were determined by gas-liquid chromatography.
The sphingosine base composition of each sphingolipid showed a characteristic common pattern, having C18-sphingosine and C18-dihydrosphingosine as the predominant bases, but there were also considerable differences in the quantity of sphingosine base among different members of sphingolipid.
A substantial amount of C20-sphingosine was found in ganglioside, and small quantities were also found in ceramide and sphingomyelin, while it was not detected in cerebroside and sulfatide. The sphingosine base compositions of cerebroside and sulfatide were very similar to each other; they contained more amounts of C18-dihydrosphingosine than those found in sphingomyelin and ceramide.
The nonhydroxy fatty acid compositions of sphingomyelin, cerebroside I and sulfatide were similar in that the saturated and mono-unsaturated fatty acids of 14-26 carbons were contained although more stearic acid was detected in sphin-gomyelin. The fatty acid composition of ganglioside and ceramide was characte-ristic, in which stearic acid was found as the predominant acid.View full abstractDownload PDF (1114K) -
Yoichiro Sasai, Yoshio Tanahashi, Tadaaki Fujiyama1969 Volume 98 Issue 1 Pages 99-106
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe activities of oxidative enzymes and cysteine desulfurase were histo-chemically investigated in familiar benign chronic pemphigus and Darier's disease. In the activities of suecinate dehydrogenase and nicotinarnide adenine dinucleotide-dependent dehydrogenases, there was no difference between the two diseases. However, the activity of nicotinamide adenine dinucleotide phos-phate-dependent dehydrogenase showed a remarkable increase in the acantholytic cells in Darier's disease as compared with those in familiar benign chronic pemphigus. A slight activity of cysteine desulfurase was found in the former, but not in the latter.View full abstractDownload PDF (2123K)
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