The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Volume 31 , Issue 1-2
Showing 1-12 articles out of 12 articles from the selected issue
  • Osamu Miura
    1937 Volume 31 Issue 1-2 Pages 1-18
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    Download PDF (1845K)
  • Kentarô Nomura
    1937 Volume 31 Issue 1-2 Pages 19-37
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    Influence of hydrogen ion concentration of the medium on the liver tissue of mouse, chiefly on the kidney tissue of rabbit was in-vestigated, attention being specially paid to the buffer potency of the tissue, that is, power of regulating the hydrogen ion concentration of the surrounding medium by the tissue cell.
    Method for tissue respiration was that of Warburg (1923, 1924).
    Hydrogen ion concentration of Ringer's solution was potentio-metrically measured before and after the manometric measurement.
    (1) Oxygen consumption of liver tissue of mouse was greater, the greater the pH was between 5.664 and 7.438.
    The pH of the Ringer's solution increased on acid side and de-creased on basic side.
    (2) Oxygen consumption of kidney tissue of rabbit, both corti-cal and medullar, was greater the greater the pH was between 5.055 and 6.900, and that at 7.611 was not different from that at 6.819.
    The pH of the medium (5.460-7.363) increased after 2 hours' manometric experiment, and in the case of 3 hours' experiment, the acid medium (5.055-6.819) became more basic and the basic medium more acid.
    (3) Oxygen consumption and carbon dioxide output of kidney tissue in CO2-bicarbonate Ringer's solution with acid pH (6.1) and basic pH (8.2) was much smaller than those in the bicarbonate free Ringer's solution buffered with phosphate mixture.
    The Ringer's solution shifted its acid pH towards basic side and the basic pH towards acid side.
    Download PDF (915K)
  • Rijuro Fukuhara, Gumpei Hiratsuka
    1937 Volume 31 Issue 1-2 Pages 38-59
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    Download PDF (1032K)
  • Toshiaki Ebina, Takashi Nakamura
    1937 Volume 31 Issue 1-2 Pages 60-71
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    (1) Die Atmungsgrösse der säurefesten Bazillen hängt von der Kulturdauer ab.
    (2) Tuberkelbazillen erhalten ihre Lebensfähigkeit auch ohne zu atmen, wenn das Medium schlecht wird.
    (3) Die Atmungsgrösse der säurefesten Bazillen ist desto grös-ser, je mehr Bazillen saprophytisch und schnell wuchern.
    (4) Die anaerobe Glykolyse der menschlichen Tuberkelbazillen ist am kleinsten.
    (5) Die aerobe Glykolyse der säurefesten Bazillen wird durch die Warburgsche manometrische Methode in Ringerlösung wah-rend kurzer Zeit nicht nachgewiesen.
    (6) In Hinsicht des Stoffwechsels gibt es keine wesentlichen Unterschiede zwischen saprophytischen, apathogenen säurefesten Bazillen und virulenten pathogenen säurefesten Bazillen, obgleich die Stärke der Atmung and der anaeroben Glykose bei apathogenen grösser ist.
    Download PDF (591K)
  • Keisuke Tanaka
    1937 Volume 31 Issue 1-2 Pages 72-80
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    Aus den vorstehend angeführten Versuchen ergibt sich vollkom-men sicher die Tatsache, dass die Variolastreptokokken als die echten Pockenerreger zu betrachten sind.
    Download PDF (530K)
  • Tetsuya Kurosawa
    1937 Volume 31 Issue 1-2 Pages 81-94
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    Download PDF (671K)
  • Misawo Ishii
    1937 Volume 31 Issue 1-2 Pages 95-105
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    In the present paper 1. a daily variation of Arakawa's reaction and chlorine content of human milk, 2. a diurnal variation of these and 3. a variation of these during one feeding have been studied. Nozaki1) delivered the first evidence that human milk positive* to Arakawa's reaction is chlorine-poor milk and a “good” milk, and that Arakawa-negative milk is chlorine-rich and a “bad” milk. In my study on these variations above mentioned, Arakawa's reac-tion and chlorine content go reversely parallel to each other, so that if Arakawa's reaction increases in intensity, then chlorine content becomes smaller and vice versa. And so it can be made a general rule that the intensity of Arakawa's reaction in a given case is re-versely proportionate to the figures of chlorine content.
    A daily variation of Arakawa's reaction, or of chlorine content is not remarkable, and as to a diurnal variation, Arakawa's reaction is generally better in the afternoon than in the forenoon, or chlorine content is generally larger in the forenoon than in the afternoon.
    As to a variation during one feeding, a “post-feeding” portion of milk is richer in chlorine, so that strippings or the last portion of a feeding is a “bad” portion. I say “bad” here, as Nozaki1) has used the word, with a good reason from Troxell's urging (Cf. Para-graph 3). And it maybe an indirect evidence that along feeding will do harm to an infant.
    By the way I have made a short report concerning the. chlorine content of human milk in three groups of diseases-l. respiratory cases which have nothing to do with a “bad” milk, 2. eczematous cases which are at least due to a “bad” milk, and 3. cases of infantile preberiberi and infantile beriberi which are due to a “bad” milk. The chlorine content was the smallest in the first group, a larger in the second and the largest in the last group (Cf. Table 5).
    And it has thus been shown that human milk rich in chlorine is a “bad” milk and that even a “good” breast can produce a “bad” milk in the last portion of feeding.
    Download PDF (492K)
  • Tetsuya Kurosawa
    1937 Volume 31 Issue 1-2 Pages 106-123
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    Download PDF (833K)
  • Kazuo Kamagata
    1937 Volume 31 Issue 1-2 Pages 124-152
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    Download PDF (1609K)
  • Gumpei Hiratsuka
    1937 Volume 31 Issue 1-2 Pages 153-170
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    An gesunden Hündinnen wurden durch Verabreichung von Was-ser, hypertonischer Kochsalzlösung, Theocin und Salyrgan Diuresen hervorgerufen und die Grössen glomerulärer Filtration (GF)und tubu-lärer Rückresorption (RR) in den Nieren mittels der Kreatininbela-stungsmethode bestimmt, es ergibt sich folgendes.
    1. Bei der Wasser- sowie Salzdiurese treten eine GF-Zunahme und eine massige Abnahme des prozentualen Verhältnisses der RR zu GF-Grösse auf.
    2. Bei der Theocindiurese nimmt die GF-Grösse deutlich zu, während das prozentuale Verhältnis der RR zu GF-Grösse im allge-meinen nicht abnimmt.
    3. Bei der Salyrgandiurese kommen eine GF-Zunahme und eine erhebliche Abnahme des prozentualen Verhältnisses der RR zu GF-Grösse zustande.
    Download PDF (935K)
  • Gumpei Hiratsuka
    1937 Volume 31 Issue 1-2 Pages 171-185
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    Es wurden an gesunden Hunden nach Injektionen von. Thyreo-glandol, Insulin und Pituitrin die BeziehungenzwischenHarrimenge und glomerulärer Filtration (GF) sowie tubulärer Ruckre sorption (RR) analysiert.
    1. BeimEinverleiben von Thyreoglandol nimmt die Harnmenge ab, weil, wenn auch die GF sich steigert, gleichzeitig auch die rela-tive Steigerung der RR auftritt.
    2. Durch Insulin tritt die Zunahme von GF von 2-3stündigem Ablauf nach der Injektion an in Erscheinung; da die RR in der ersten bzw. zweiten Stunde nach der Injektion mit der Zunahme von GF parallel oder zuweilen stärker als diese zunimmt, erfährt die Harn-menge oft eine Abnahme, jedoch steigert sich hernach die Harn-absonderung, weil die RR in weiterem Verlauf relativ gehemmt wird.
    3. Pituitrin ruff immer die Zunahme von GF hervor. Die RR erhoht sich mit derZunahme von GF; das Verhältnis der RR zur GF, also der Prozentsatz der RR zur GF zeigt je nach jeweiligem Zustand des betreffenden Versuebstieres entweder keine nennenswerte Ver-änderung odereine Zunahme. Wenn der Prozentsatz der RR zur GF deutlich erhöht ist, tritt eine Hemmung der Diurese ein, bei weniger erheblicher Erhöhung tritt eine Förderung der Diurese zutage. Für die resorptionssteigernde Wirkung desPituitrins scheint ein bestimm-tes Optimum vorhanden zu sein; in denjenigen Fällen nämlich, in de-nen der Prozentsatz der RR zur GF vor der Pituitrininjektion relativ niedrige Werte aufweist, lässtsick eine intensive Förderung der RR erkennen.
    Download PDF (805K)
  • Takeo Mutow
    1937 Volume 31 Issue 1-2 Pages 186-196
    Published: May 31, 1937
    Released: November 28, 2008
    JOURNALS FREE ACCESS
    The present investigations were made on dogs in order to ascer-tain whether or not the heat-tachypnoea of the reflex nature is still causable after removing the centers for the body temperature regulat-ing mechanism, as that of the central nature, such as is elicitable by warming the carotid arteries.
    By raising the environmental temperature, the dog, without nar-cotizing, reacted by heat-tachypnoea; at its onset the body tempera-ture was usually normal or a little decreased, or only slightly raised, as well known.
    The corpus striatum, the thalamus opticus, and the tuber cine-rum were removed; no narcosis was used, and about one hour was. allowed to elapse before the next warming experiment for recovery from the operative shock.
    Afterwards no heat-tachypnoea of the reflex nature was elicited. contrary to that of the central origin. Some acceleration in the re-spiratory rate was always preceded by a material rise of the body temperature; that is, there was no evidence of heat-tachypnoea of the reflex nature occurring.
    In the majority of cases where some considerable tachypnoea, such as 90-200 breathing per min., appeared after the brain opera-tion on raising the environmental temperature or on warming the -carotid arteries (S ato and Nemoto), whereby the body temperature was raised, the brain lesion was identical in essential points to that causable by the decerebration of Sherrington. This shows: So far as the midbrain remains nearly intact or even if the anterior col-liculi be excluded, although the brain portions anteriorto it be wholly removed or destroyed, the heat-tachypn oea is capable of being brought about by raising the temperature thereof or the body temperature.
    From the above outcome it may be justifiable to conclude:
    (1) The central mechanism for regulating the body temperature is indispensable for causing the heat-tachypnoea of the reflex origin.
    (2) The heat-tachypnoea of the central origin is induciable if the brain anterior to the midbrain or even the anterior colliculi are excluded.
    Download PDF (1013K)
feedback
Top