The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Volume 68, Issue 2
Displaying 1-11 of 11 articles from this issue
  • Studies on Tuberculosis in Infancy and Childhood. 3 rd Report
    Tsuneo Arakawa, Mizuo Oota, Yuji Sato
    1958 Volume 68 Issue 2 Pages 105-113
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Erythrocytes sensitized with tuberculin-polysaccharide were identified in the circulating blood from 89 cases (32.0%) out of 278 patients under 13 years of age.
    The incidence of the cases with the sensitized erythrocytes was higher below 7 years than above 7 years of age.
    Antibody against tuberculin-polysaccharide in serum was not detected in any of the cases with the sensitized erythrocytes.
    Positive Mantoux reaction, tried with the old tuberculin of a dilution of 1:2000, was found in only 33.7% out of 74 cases with the sensitized erythrocytes under 7 years of age.
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  • Kazukuni Yamashita, Masaaki Inoue, Hirobumi Akimoto
    1958 Volume 68 Issue 2 Pages 115-117
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Four dogs, anesthetized with Evipan-sodium, were experimented on. The adrenal venous blood specimens were collected through the lumbar route and were analysed for adrenaline by the chemical method of Bloor and Bullen.
    While the administration of KCl in a dose of 30-33mg. per kg. caused a definite increase in the adrenaline secretion, the injection of KCl in the same dose as before plus MgCl2 in a dose of 10mg. per kg. produced no increase or only a small increase in the adrenaline secretion.
    From these experimental results, it is concluded that MgCl2 is capable of antagonizing the accelerating action of KCl on the adrenaline secretion.
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  • Second Report On MPSs (Mucopolysaccharides) I
    Hiroya Kawasaki
    1958 Volume 68 Issue 2 Pages 119-132
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1. Group mucopolysaccharides MPSs I, cancerous and non-cancerous, in the First Report were examined physically, chemically and biologically.
    2. Noticeable findings will be enumerated.
    i. The cancerous group A and B substances are very weak in group A or B activity, in contrast with the corresponding non-cancerous group substances.
    ii. The cancerous mucopolysaccharides differ in composition from the non-cancerous, the sialic acid contents of the former being higher than those of the latter and the glucosamine/galactosamine ratio remaining the same irrespective of blood group in the former but varying from group to group in the latter.
    iii. The cancerous substances rotate sodium-light in resembling grades and that more to the left than the non-cancerous, while the non-cancerous are differently levorotatory depending on blood group.
    iv. The molecular weight of the cancerous group A mucopolysaccharide is lower than that of the non-cancerous substance of the same blood group.
    v. MPSs I are toxohormone active, though weak.
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  • Tatuzi Suzuki, Ikuro Tanaka, Kazukuni Yamashita
    1958 Volume 68 Issue 2 Pages 133-137
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Bei den mit Evipan-natrium narkotisierten Hunden wurde das Neben-nierenvenenblut mit der Lumbalroutemethode entnommen. Die Bestimmung der Adrenalinmenge wurde mit Hilfe der kolorimetrischen Methode von Bloor and Bullen ausgeführt. Die intravenosen Injektionen des Carbarminoylcholins and des Acetylcholins in Dosen von 0, 3-0, 4mg. pro kg. Körpergewicht wurden vor und nach der Darreichung des Eserins (0, 3mg. pro kg.) angestellt.
    Die Verstärkung der adrenalinsekretionsfördernde Wirkung von Acetylcholin durch eine vorangehende Verabreichung von Eserin war in alien Fällen nachweisbar. Dagegen vermochten wir keine unverkennbare Verstärkung der Wirkung von Carbaminoylcholin durch Eserin zu konstatieren.
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  • Koiti Motokawa, Mitsuru Ebe, Mitsuo Komatsu, Kei Watanabe
    1958 Volume 68 Issue 2 Pages 139-149
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    It was shown by the method of electrostimulation of the eye that spreading induction was refracted when a prism-shaped retinal image was formed on the way of its propagation through the retina.
    1. The degree of refraction depended on the intensity and also the wave-length of light illuminating a prism-shaped patch whose image was formed on the retina.
    2. The propagation velocity of spreading induction was measured to investigate its dependence on the intensity and the wave-length of adapting light. In the retina adapted to white light the velocity was higher than in the dark-adapted retina, while in the retina adapted to colored light the velocity was found lower than in the dark-adapted retina.
    3. The refractive index computed from propagation velocities was in satisfactory agreement with that determined by measurements of refraction.
    4. It was shown by many examples that the law of geometrical optics holds for spreading induction in the human retina.
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  • Report V On Naegeli's Opinion and Significance of Leucocytosis and Leucopenia in Infectious Diseases
    Akira Saito
    1958 Volume 68 Issue 2 Pages 151-163
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • CCXVI. On Conditions of Acetolyzing Molisch-positive Mucopolysaccharides
    Hajime Masamune, Hyogo Sinohara, Takasi Okuyama
    1958 Volume 68 Issue 2 Pages 165-171
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    The group mucopolysaccharide from pig stomach mucus was acetolyzed with reagents containing various amounts of H2SO4 for various durations at various temperatures to determine the best conditions for obtaining disaccahrides and oligosaccharides excepting disaccharides.
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  • Third Report On MPS (Mucopolysaccharide) II
    Hajime Masamune, Hiroya Kawasaki, Sin-iti Abe
    1958 Volume 68 Issue 2 Pages 173-179
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1. MPSs II, cancerous and non-cancerous, in the First Report were examined physically, chemically and biologically.
    2. They proved homogeneous electrophoretically and absorbed no ultraviolet light near 260 mμ.
    3. They are made up of same components.
    4. However, glucosamine/galactosamine ratio and contents of glucose, of sialic acid and of L-fucose vary from substance to substance.
    5. Their optical rotations resemble each other.
    6. They don't possess group activity within ABO classification. They are also devoid of KIK- and toxohormone-activity.
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  • CCXVIII. N-Acetyl-4, 6-benzylidene-glucosamine
    Hajime Masamune, Takasi Okuyama, Hyogo Sinohara
    1958 Volume 68 Issue 2 Pages 181-184
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • Kiichiro Suzuki, Yoshio Toratani, Masumi Tokunaga, Yoshikazu Magumi
    1958 Volume 68 Issue 2 Pages 185-191
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    By means of Motokawa's method of electric flicker (EF), we measured variations of electric flicker values (EFV) of 5 subjects caused by hyperpnea, the inhaled gases being air, 100% O2 and 1% CO2 in 2. Measurements by an ear oximeter were carried out in parallel.
    1. During 5 minutes' deep breathing of air, both EFV and oximeter values (Oxi-V) increased.
    2. Also by deep breathing of pure oxygen, both kinds of values increased.
    3. In case of 100% O2 inhalation (normal breathing), Oxi-V increased, but no change occurred in EFV.
    4. In case of hyperpnea of 1% CO2 in O2, Oxi-V increased, while no change could be found in EFV.
    From these findings it was concluded that the change in EFV by hyperpnea is due to acapnia.
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  • Report I Studies on the Experimental Methods
    Toshio Sato, Satoru Akiba, Hisanobu Ise, Masao Yamanaka
    1958 Volume 68 Issue 2 Pages 193-205
    Published: August 25, 1958
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    We have reported in the above a newly devised clinically simple and easy method of our own improving upon the method previously devised by Sato, one of the present authors, for tracing the electrophoretic pattern of liver protein.
    We made investigations from several angles on the biochemical nature of the fractions appearing in the electrophoretic patterns thus obtained and arrived at the conviction that the liver protein is mainly composed of fractions electrophoretically identical with the four type of globulin found existing in human plasma. We rescrutinized our method for the interference by the blood content of the specimens, the merits of the buffer solution used and the reproducibility of the patterns, and have obtained satisfactory conclusions on all these points.
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