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Volume 3 (1922)
- Issue 5-6 Pages 305-
- Issue 3-4 Pages 163-
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Volume 3, Issue 5-6
Displaying 1-13 of 13 articles from this issue
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MATAJURO YAMAKITA1922 Volume 3 Issue 5-6 Pages 305-316
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. In an amount larger than 0.15 per cent concentration to the ammonia water the addition of potassium oxalate diminishes the values of the oxygen capacity of human blood observed by the ferricyanide method. In the case of the blood of rabbits this effect is produced by an amount larger than 0.2 per cent concentration.
2. The sodium citrate has a similar effect but less marked than potassium oxalate. It produces a recognizable decrease in the observed value of the oxygen capacity of blood in a concentration greater than 0.75 per cent to the ammonia water.
3. Their influence on the observed value of the oxygen concentration is due to their checking action on the laking of blood.
4. There are individual variations in the magnitude of the decrease in the estimated oxygen amount caused by the addition of potassium oxalate of sodium citrate, partly owing to the individual differences of the resistance of the plasma membrane of red corpuscles.View full abstractDownload PDF (372K) -
S. Yamakawa, M. Kashiwabara1922 Volume 3 Issue 5-6 Pages 317-332
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
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Tsunetaro Konno, Kikuo Sakai1922 Volume 3 Issue 5-6 Pages 333-340
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Bei einer Nahrungsmittelvergiftung wurde eine Art Mäusety-phusbazillen von vielen erkrankten Personen nachgewiesen, welche der Aoki'schen Einteilung zufolge der Aertryckform gehören.
2. Diese Stämme waren immer geneigt, eine andere Form der Mäusetyphusbazillen neu zu bilden, welche nach der Aoki'schen Ein-teilung zu den Mäusetyphusbazillen im engeren Sinne gehören muss.
3. Wenn man unsere Stämme der Aertryckform auf Schrägagar mehr als 20mal hintereinander umimpft, so wird die Zahl der Kolonien der originalen Form von der der anderen übertroffen, so das diese mehrmals umgeimpfte Kultur in Paratyphus B-Immunserum so stark wie Paratyphus B-Bazillen selbst agglatinieren kann.
4. Um unseren Stamm immer rein zu erhalten muss man die Reinkultur von einer isolierten Kolonie immer frisch herstellen, welche agglutinatorisch als Aertryck typisch reagieren kann.
5. Auf diese Weise konnten wir mit unseren Stämmen der Aer-tryckform bei Kaninchen immer solche Sera herstellen, welche Mäusety-phusbazillen bis zum Titer, aber Paratyphus B-Bazillen ganz schwach agglutinieren.View full abstractDownload PDF (361K) -
X. Mitteilung: Über das agglutinatorische Verhalten Von Paratyphus B=Bazillen und Mäusetyphusbazillen den Sera aus den Mäusetyphusbazillen der Aertryckform und GärtnerbazillenKikuo Sakai1922 Volume 3 Issue 5-6 Pages 341-351
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Es wurden 76 Stämme Paratyphus B-Bazillen, welche bei typhöser Erkrankung von Menschen gezüchtet worden waren, und ferner 46 Stämme Mäusetyphusbazillen, welche teils bier im Institute bei Tieren gezüchtet, tells von verschiedenen Instituten als Reinkul-turen bezogen wordeu waren, in den von Aoki angegebenen dreierlei lmmunsera, nämlich Pb 14, Ms 2 und Ms 34, agglutinatorisch unter-sucht. Das Serum Pb 14 stellt Paratyphus B-Bazillen, das Serum Ms 2 Mäusetyphusbazillen im engeren Sinne und das Serum Ms 34 Mäuse-typhusbazillen der Aertryckform dar. Es wurde dabei festgestellt, dass das von Aoki bei Paratyphus B-Bazillen und Mäusetyphusbazillen angegebene agglutinatorische Schema bei diesen Stämmen ganz regel-mässig nachweisbar ist. Alle Stämme Paratyphus B-Bazillen wurden nämlich im Serum Pb 14 und im Serum Ms 2 ebenso stark wie der Titer aber in dem anderen Serum Ms 34 ganz schwach beeinflusst. Alle Stämme Mäusetyphuslazillen agglutinierten im Serum Ms 34 und Ms 2 ohne Ausnahme bis zum Titer; aber sie alle wurden vorm Serum Pb 14 nicht im gleichen Grade agglutiniert. Ein grösserer Teil von ihnen reagierte nämlich in demselben Serum ebenso stark wie der homologen Stamm, nur ein kleinerer Teil ganz schwach. Zum ersteren Teil gehörte der Stamm Ms 2 und zu letzterem der Stamm Ms 34.
2. Einigc Abweichungen, welche darin bestehen, dass ähnlich wie Mäirsetyphusbazilien reagierende Stämme unter den Stämmen Para-typhus B-Bazillen, umgekehrt wie Paratyphus B-Bazillen reagierende Stämme unter den Stämmen Mäusetyphusbazillen nachgewiesen wurden, dürften dadurch zustande gekommen sein, dass die betreffenden Stämme geneigt und befähigt sind, sich von einer Bakterienart in die andere umzuwandeln.
3. Wie schon Sobernheim im und Seligniann beobachtet hatter, war auch ich imstande unter den oben genannten Bakterien solche Stämme nachzuweisen, welche in einem bestimmten Gärtnerserum ebenso stark wie der homologe Stamm reagieren können. Diesc. Stämme wurden bei uns nicht selten gefunden.View full abstractDownload PDF (578K) -
KUMAO YAMAKAMI1922 Volume 3 Issue 5-6 Pages 352-362
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDer Chlorgehalt des Bhites nimmt ausnahmslos in der Erstickuna zu. Das Chlor tritt in der Erstickung aus den Geweben ins Blut aus.View full abstractDownload PDF (499K) -
SACHIKADO MORITA1922 Volume 3 Issue 5-6 Pages 363-413
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
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I. Under Narcosis and Hypnosis. (A Contribution to the Theory of Narcosis.)MATAJURO YAMAKITA1922 Volume 3 Issue 5-6 Pages 414-495
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
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II. The Effect of Excited Activity of the Brain on its Oxygen Consumption and Blood Flow, and the Action of Drugs on the Cerebral VesselsMATAJURO YAMAKITA1922 Volume 3 Issue 5-6 Pages 496-537
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
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III. The Effect of Hot and Cold Applications to the Head on the Gaseous Exchange of the BrainMATAJURO YAMAKITA1922 Volume 3 Issue 5-6 Pages 538-555
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
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IV. The Relation of the Blood Flow to the Oxygen Consumption in the BrainMATAJURO YAMAKITA1922 Volume 3 Issue 5-6 Pages 556-566
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
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MATAJURO YAMAKITA1922 Volume 3 Issue 5-6 Pages 567-607
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. The oxygen consumption and carbon dioxide production of normal non-nucleated red corpuscles stored in the ice-chest is very slow; in the ice-chest, the temperature of which is 4°-7°C., in about 70-80 hours the oxygen content of the blood is lost by about 50-80%, while in blood mixed with adrenaline there is only a decrease of about 15-40% in the same time.
2. The rate of reduction of normal blood stored in the incubator of 34°-38°C. is very great in comparison with that in the ice-chest; in about 10 hours it acquires a darkish red colour, and in about 15-50 hours the oxygen content is lost by about 80-100%, while in blood mixed with adrenaline, there is only a decrease of about 50-60%.
3. Adrenaline decreases the rate of the increase in the carbon dioxide content of the blood stored in the ice-chest or the incubator. Generally, the influence of adrenaline on the production of carbon dioxide is greater than that on the oxygen consumption; in both the blood with and that without adrenaline, the oxygen consumption and the carbon dioxide productgion do not run closely parallel to each other; even after the entire loss of the oxygen content, the production of carbon dioxide can continue.
4. There is fairly large variation in the results of experiments on the gaseous metabolism of blood stored in the ice-chest and the incubator; this variation is due especially to the temperature and the haemoglobin content.
5. While the effect of adrenaline on the gas metabolism of blood is very marked, it has no influence on the oxygen capacity of the blood.
6. The reduction of haemolyzed blood, compared to that of normal blood is very remarkable; when the blood is haemolyzed, the time taken for complete reduction is shortened and by storage in the incubator for ten hours its oxygen content is entirely lost, while of adrenaline is added, the rate of the reduction of blood is markedly retarded and nearly equal to that in the case of non-haemolyzed normal blood.
No difference in the efficacy of adrenaline on the haemolyzed blood and the non-haemolyzed is found. The action of adrenaline on the gaseous metabolism of blood does not depend on the presence or not of plasma membrane of blood corpuscles.
7. Adrenaline reduces also the gaseous metabolism of serumless washed corpuscles as distinctly as that of normal blood; namely the efficacy of adrenaline has no relation to the presence or not of serum.
8. Adrenaline acts similarly on the gaseous exchange of washed and haemolyzed blood. Thus it has no relation to cell membrane, cell structure or serum.
9. Adrenaline retards the rate of reduction of oxyhaemoglobin solution in which no stroma is contained, thus the action of adrenaline has no relation to stroma of red corpuscles.
10. The inhibitory action of the adrenaline solution on the gaseous metabolism of blood is notdue to chloretone contained in it, nor is it due to its acidity. Hydrochloric acid solution of the same acidity increases the rate of reduction of blood.
11. Adrenaline also retards the rate of reduction of blood when it is treated with reducing gas. When the blood is reduced with carbon dioxide gas, the effect is more marked than when nitrogen gas is used.
12. Adrenaline does not accelerate the rate of oxidation, but on the contrary has a tendency to retard it.
13. For a few minutes after the intravenous injection of adrenaline, just during the rise of the blood pressure the blood of the external jugular vein is red-colored; the difference between the quantities of oxygen contained in it and in the arterial blood becomes small. This action of adrenaline has no relation to the state of the blood flow.
14. The effect ofadrenaline injected into the body can be proved in vitro in the blood; of the blood taken within a few minutes after the intravenous injection of adrenaline, the gaseous exchange in vitro is markedly decreased.View full abstractDownload PDF (1676K) -
MATAJURO YAMAKITA, TOYOJIRO KATO1922 Volume 3 Issue 5-6 Pages 608-652
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS(1) The arterial oxygen unsaturation in 10 normal adults and some patients with normal heart and lung findings was found on an average to be 1•56 c. c. per 100 c. c. blood, ranging from 0•85 c. c. to 1•86 c. c. This unsaturation was apparently reduced by oxygen inhalation.
(2) In 8 cases of pulmonary tuberculosis which was not accompanied by cyanosis, oedema or high fever, the average oxygen unsaturation was 2•04 c. c. per 100 c. c. blood; in chronic pulmonary disease, even when the lesion was found in the whole lungs, the increase in the oxygen unsaturation was comparatively slight. The arterial oxygen unsaturation in pulmonary tuberculosis was decreased through about 15% with the ordinary mask method of oxygen inhalation.
In 7 patients with bilateral or unilateral pleurisy there were various degrees of arterial oxygen unsaturation, ranging from 1•35 c. c. to 5•38 c. c. per 100 c. c. blood, therein seropneumothorax produced suddenly being accompanied by the most marked anoxaemia. When pleurisy was complicated with pulmonary tuberculosis, the arterial anoxaemia was comparatively marked, and in pleurisy with lost exudation the oxygen unsaturation was less augmented. Oxygen inhalation was able to diminish that increased oxygen unsaturation, its efficacy being rather greater than in pulmonary tuberculosis.
In 9 cases of heart disease, there was an arterial anoxaemia proved, the degree of which was remarkably pronounced in decompensated cases with cyanosis. Oxygen inhalation lowered the arterial anoxaemia distinctly in the cases not accompanied by decompensation, while in the decompensated cases it brought scarcely any benefit.
(3) By inducing unilateral opened pneumothorax in rabbits, the oxygen unsaturation was raised to about 2-6_??_ times. The effect of oxygen administration in this case was very slight.
In unilateral closed pneumothorax the anoxaemia was less marked, while bilateral closed pneumothorax produced such a pronounced anoxaemia as opened pneumothorax. The effect of oxygen inhalation subsequent to the bilateral closed pneumothorax was not significant, while in unilateral closed pneumothorax the increased oxygen unsaturation was promptly reduced by it to about a half.
By introducing a certain amount of olive-oil into the pleural cavity the oxygen unsaturation was raised about 3 times, and this anoxaemia was fully corrected by oxygen inhalation.
Occlusion of a main bronchus increased the arterial oxygen unsaturation about 2-6 times, and in this case the effect of oxygen inhalation accomplished comparatively little, thereby the anoxaemia being reduced to about _??_.
The introduction of fluid paraffin into the bronchial tree of the lungs gave rise to a marked elevation of the arterial oxygen unsaturation.
Consolidation of some parts of the lung due to injection of silver nitrate into the lung increased the arterial oxygen unsaturation. The beneficial effect of oxygen inhalation on the anoxaemia was proved also in this case.
Marked respiratory depression caused by the injection of morphine raised the arterial oxygen unsaturation to 2-3 times. This enlarged oxygen unsaturation was reduced to about one tenth by oxygen inhalation, while the respiratory rate showed further reduction, finally bringing on a complete apnoetic state during the inhalation.
When the blood pressure fell to half the original height by the injection of chloral hydrate, there was a slightly increased oxygen unsaturation of the arterial blood, but when the pressure was lowered to about 20mm. Hg the unsaturation was enormously augmented. During oxygen inhalation, this increased oxygen unsaturation was distinctly corrected, but the lowered blood pressure remained unaffected.View full abstractDownload PDF (1831K) -
RYO TSUKASAKI1922 Volume 3 Issue 5-6 Pages 653-657
Published: December 30, 1922
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe human serum obtained from a dead body is precipitated by the addition of alcohol. After filtering it, the remainder is dried and injected into the vein of a rabbit. I was able to immunize the animal by it and get moreover a highly active and specific precipitin serum. Serum powder thus made is preservable for a long time.View full abstractDownload PDF (226K)
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