The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Volume 79, Issue 3
Displaying 1-11 of 11 articles from this issue
  • Isao Kon
    1963 Volume 79 Issue 3 Pages 209-231
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1) By means of histometrical treatments pulmonary arteries of autopsy cases were reduced to the state in which internal elastic membrane was perfectly extended. The distance from the center of exactly circular arterial lumen to the middle point of the muscular coat was defined as anatomical radius R and the thickness of the media as D. In the region from R=100μ to R=1000μ, the relation of R and D could be expressed by a general formula D=aRb, where a and b were constants.
    2) Regression equations of pulmonary arteries of autopsy cases which were regarded to have had normal pulmonary circulation were determined in the above-mentioned region, and the values of estimated D at R=100μ was calculated from the regression equations of individual cases. Upper rejection limit of estimated D of normal pulmonary arteries was determined. When the estimated D of a certain autopsy case exceeded the upper rejection limit, the case was regarded to have hypertrophied muscular coat and pulmonary hypertension. The method was found effective in screening relatively pronounced pulmonary hypertension.
    3) The presence of moderate medial hypertrophy as a result of relatively mild pulmonary hypertension could be estimated by comparison of the regression equation of the group to that of normal pulmonary arteries.
    4) Medial hypertrophy of pulmonary artery was confirmed in cases with prolonged arterial hypertension in systemic circulation and was found to be more prominent in the group with uremie pneumonitis than in the group without the lesion in spite of uremia.
    5) The pathogenesis of uremic pneumonitis was discussed in reference to pulmonary hypertension. The presence of pulmonary hypertension was regarded to be one of the important pathogenic factors in precipitating pulmonary lesions of the type of “uremic pneumonitis”.
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  • Shoichi Yamagata, Akira Ohneda
    1963 Volume 79 Issue 3 Pages 232-241
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Dietary intake was studied in 127 diabetic patients who were admitted to our Department.
    The age at onset of diabetes mellitus was distributed mostly between the fourth and sixth decades.
    The maximum weights at or prior to onset of this disease were above the standard zone of weight in 89 diabetics (70.1%) while they were below it in 4 diabetics (3.1%). The body weights of 39 diabetics (30.9%) after manifestation of this disease were over the standard zone of weight whereas they were below the standard zone of weight in 26 diabetics (20.4%).
    Neither correlation between dietary intake and diabetic types nor between dietary intake and heredity was observed. There was a correlation between dietary intake and obesity, and an increased intake of protein and fat and of calories was found in a number of obese diabetics.
    Any correlation between consumption of sugar and the etiology of diabetes mellitus was not observed.
    An increased intake of total calories was observed in many of those cases who were well off economically, such as a university professor, an administrator of a company, and so on.
    In connection with the etiological factors, heredity was proven in 30 diabetics or 24 per cent, an increased intake of calories in 63 diabetics or 50 per cent, and obesity in 89 diabetics or 70 per cent. Twenty-four diabetics (19 per cent) did not have any of the above mentioned etiological factors at all.
    The results obtained in this study suggest that obesity and an increased dietary intake play an important role in the etiology of human diabetes mellitus.
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  • IV. Correlation of Plasma Protein Bound Polysaccharides and Plasmin System
    Masahiro Maki, Eisei Kikuchi, Kazuma Nagasawa
    1963 Volume 79 Issue 3 Pages 242-249
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    The following results were obtained by simultaneous assay of PBP and plasmin system with special reference to blood samples obtained during gynecological surgery.
    1. Sensitivity order of substrates to plasmin was as follows: Fibrin>fibrinogen>casein>TAMe.
    2. Significant elevations of fibrinolysis and fibrinogenolysis of the euglobulin fraction were found after spinal anesthesia but no remarkable influences were found in the caseinolytic and TAMe-lytic activity.
    3. The relation between the levels of PBP in plasma and trypsin inhibitor activity was proved to be significant.
    4. By the addition of some glucidamins and polysaccharide sulfates in vitro, and action of trypsin was lowered to a considerable degree.
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  • Noriko Katsushima
    1963 Volume 79 Issue 3 Pages 250-266
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    A simultaneous estimation of peroxidase in plasma and per single myeloid cell was carried out by my own colorimetric method upon 42 normal subjects and 101 cases with various disorders. Even though the cases examined were small in number, a certain speculation could be drawn as was shown in Table XIII. The abnormally high values for peroxidase per single myeloid cell were found in the cases with neoplasm, mild form of progressive muscular dystrophy and lupoid hepatitis. Less probably it might be said that in the cases with chronic hepatitis, glycogen storage disease, albinism, ecthyma, sepsis and rheumatic fever an abnormally high level of peroxidase per single myeloid cell would be found.
    The extremely high values for plasma peroxidase were found in the cases with the peroxidase positive myeloblastic leukemia. A considerable high value for plasma peroxidase was found in one case with encephalitis of unknown etiology.
    The abnormally low levels for peroxidase per single myeloid cell were found in the cases with chronic agranulocytosis, and gargoylism, and less probably in the cases with hypochromic anemia, acquired hemolytic anemia, osteochondrodystrophy and rheumatoid arthritis.
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  • Nobukazu Chida
    1963 Volume 79 Issue 3 Pages 267-273
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • Hiyoshimaru Oyamada
    1963 Volume 79 Issue 3 Pages 274-280
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • Takao Fukuda
    1963 Volume 79 Issue 3 Pages 281-292
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Two efferent lymphatic currents were confirmed in the present study:
    (1) Perivenous, which originated from the subintimal spaces of the veins, and (2) periarterial, which started from the follicles.
    No afferent currents were detected.
    Evidence is still required to clarify the problem, whether the splenic blood circulation is of a closed or open type. Splenic lymphatics should be investigated in reference to the aspect of splenic blood circulation.
    Die Existenz von tief-liegenden Lymphwegen der menschlichen Milz wurde betont.
    Es waren zwei Systeme von abführenden Lymphwegen: (1) perivenöses and (2) periarteriales System.
    Nirgends wurden zuführende Lymphwege entdeckt.
    Der Zusammenhang zwischen Blut- und Lymph-zirkulation wurde zugleich cliskutiert.
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  • Akira Nukada, Hisanori Nagata, Tatsuo Ishizaki
    1963 Volume 79 Issue 3 Pages 293-305
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Blood pressure of Japanese male and female subjects with various arm size was experimentally measured with cuffs of various length and width and the following results were obtained.
    1) In subjects with large arm, readings of both systolic and diastolic blood pressure were higher with the shorter cuff and lower with the long cuff. If cuffs longer than 26 cm were used, the variation of blood pressure reading resulting from the use of different length of cuff became very small and negligible even in subjects with arm of more than 30 cm in circumference.
    2) The readings of both systolic and diastolic blood pressure were unlimitedly lower if the wider cuff was used. Both in male and female subjects, this relation between width of cuff and blood pressure reading was found to be almost same in any arm size group.
    From the point of view that size of cuff should be standardized to minimize the systematic errors resulting from the use of different size of cuff, the authors suggested that the length and width of cuff for Japanese adults should be strictly fixed to 26 cm and 14 cm respectively.
    The reasons for the choice of this standard were also discussed.
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  • Toshitake Ishii
    1963 Volume 79 Issue 3 Pages 306-308
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Dihydrotachysterol-pretreated rats were injected subcutaneously with different metallic salts. It was observed that if an element is active in producing cutaneous caleinosis as a cation, it is inactive as an anion, and vice versa.
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  • Tetsuo Maki, Koichi Yoshida, Akio Koizumi, Toshio Takahashi
    1963 Volume 79 Issue 3 Pages 309-318
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    A case of a 38 year old, male, was presented here in which local recurrence at the anastomosis line was confirmed following curative operation for gastric cancer probably due to implantation of cancer cells exfoliated from the carcinomatous ulcer into the lumen.
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  • Tetsuo Maki, Susumu Majima, Koichi Yoshida, Toshio Takahashi
    1963 Volume 79 Issue 3 Pages 319-333
    Published: April 25, 1963
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Download PDF (4653K)
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