In rabbits the heat-puncture was tried with regular determina-tions of the body temperature and of the sugar concentration of blood samples from the vein of the denervated ear. The skull bone was perforated and the dura mater opened on the previous day.
When puncturing the rabbits they were not fastened on the table, but were held in the hands of an assisstant. It is needless to say that no narcotica was resorted to. The determinations were carried out until the body temperature fully recovered the initial value, that is, for three to four days.
The body temperature ascended to 41-41.7° in 8 rabbits; a slight hyperglycaemia occurred in some of them, but it was only transi-tory. It is reasonable to take it as the so-called operation hyper-glycaemia.
In another set of experiments, the heat-punctured rabbits and the normal ones, as the control, were heated by means of a gas stove. In the control rabbits the body temperature was raised to 40°-41° when the environmental temperature was 34-39°, and a slight hyperglycae-mia was induced in some cases, not invariably. The body tempera-ture was 39°-41° at that time. The body temperature of the heat-punctured rabbits ascended considerably viz: to 43-445°. When the body temperature rose above 40-42°, the blood sugar concentration began to increase and 2-4 hours later the increase reached the acme, viz: 0.14-0.28% mean 0.2%. This acme appeared 1-2 hours later than the acme of the body temperature.
To recapitulate the summary; while the heat-puncture alone does not bring about any hyperglycaemia in rabbits, it is capable of inducing a remarkable hyperglycaemia if combined with overheating whereby a considerable hyperthermia results
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