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Volume 109 (1973)
- Issue 4 Pages 309-
- Issue 3 Pages 205-
- Issue 2 Pages 97-
- Issue 1 Pages 1-
Volume 109, Issue 2
Displaying 1-10 of 10 articles from this issue
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HAJIME HOSHI, TOM MORI1973 Volume 109 Issue 2 Pages 97-111
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSEffect of long-lasting suppression of the thymic lympho-poiesis on the development of the splenic lymphoid components was investigated using male white leghorn chickens. The thymic lobes of young chickens were kept rudimentary and alymphocytic by an exposure to 650 r of whole body X-irradiation at one day of age and subsequent repeated exposures of the neck to 650 r X-rays. The bursae showed no morphological evidence of damage to the lymphopoietic activity. In the spleens, a near-complete loss of the small lymphocyte population and a marked suppression of the germinal center formation were observed, while the periellipsoidal lymphoid tissue and the plasma cell series, both being the bursa-dependent elements, were well developed. Lymphocytic repopulation in the thymus after the termination of the repeated X-irradiations was followed by the appearance: of small lymphocytes and the development of germinal centers in the spleen. These observations lead us to conclude that the germinal center formation in chickens is not merely a bursa-dependent process but may be influenced by certain thymus-dependent factor or factors.View full abstractDownload PDF (3917K) -
SHIUICHI INOUE1973 Volume 109 Issue 2 Pages 113-120
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSBy measuring the gastrointestinal pH values in the patients with diseases in the upper gastrointestinal tracts using pH meter and pH telemetry methods, the following results were obtained. The pH in the lower esophagus ranged from 6.3 to 7.5 and averaged 6.7. The pH in the gastric body ranged from 1.0 to 7.0 in the gastric ulcer and below 1.8 in the majority of the duodenal ulcer and co-existing gastroduodenal ulcer. The pH in the chronic gastritis rose in parallel with atrophic changes, and the pH in many cases with gastric cancer and polyp ranged from 3 to 7 and 7, respectively. The gastric antral pH was 1.99; it was attributed to the gastric secretion. The duodenal bulbar pH was 6.46 and it fluctuated after administration of gastric secretory stimulant. The pH in the second portion of duodenum was 6.35.View full abstractDownload PDF (368K) -
GORO KAKIZAKI, NOBORU NOTO, TAKAYUKI SAITO, YOSHIYUKI FUJIWARA, TETSUN ...1973 Volume 109 Issue 2 Pages 121-133
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSLaboratory diagnostic tests for pancreatic diseases were carried out by examination of samples of parotid saliva in 22 patients, of whom 9 were with pancreatic disorders and 13 with disorders of other organs or systems. Trend analyses of the data thereby obtained revealed the approximate borderline values (lower for pancreatic diseases and higher for non-pancreatic disorders) for the rate of salivary secretion, its maximum bicarbonate concentration and amylase secretion to be 0.6ml per minute, 20 mEq/L, and 1, 000 units per kg of body weight, respectively. The results of the present study emphasize potential usefulness of the examination of parotid saliva as a reliable diagnostic means for diseases of the pancreas.View full abstractDownload PDF (1854K) -
EIICHI SATO, NOBUAKI SASANO, TOSHIRO SATO, KANEO KIKUCHI1973 Volume 109 Issue 2 Pages 135-153
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSLipiodol, very small in amount, was injected into the gastric propria mucosae immediately after laparotomy for gastric ulcer and neoplasms. The lipiodol diffusion on radiographs of the normal mucosa was in most cases limited in an elliptic or rectangular form on plane phases and in a narrow rectangular form on cross-sectional phases. In cases of mucosal atrophy frequently associated with intestinalization, the diffusion was irregular on plane phases and was particularly extensive in the deepest and/or middle layer of the mucosa on cross-sectional phases. In the submucosa, lipiodol flowed to a considerable distance through the lymphatics, predominantly toward the cardia and greater curvature and in general centrifugally from the foci of peptic ulcer or carcinoma. In cases of injection into the regenerated mucosa of peptic ulcer, lipiodol easily diffused into the subjacent scar and traveled fairly far and wide along the fiber bundles. In cases with lymphatic invasion of carcinoma in the submucosa, the lipiodol flow from the mucosa was frequently blocked at the lamina musclaris mucosae or stemmed just after passing it.View full abstractDownload PDF (5282K) -
TAKESHI SHIMIZU, MASAHIRO MIENO, KAZUKUNI YAMASHITA1973 Volume 109 Issue 2 Pages 155-161
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAn immediate effect of head X-irradiation on the hypo thalamic-pituitary-adrenal and -gonadal systems was investigated in adult male dogs. Under pentobarbital anesthesia, the animals were given 200-1, 000 R of X-irradiation to their heads. During a period of 125 minutes after ex-posure, adrenal and testicular venous blood samples were collected intermittently, and were analyzed for 17-hydroxycorticosteroids and 17-oxosteroids, respectively. After X-irradiation of 200 R, there was a subtle decrease in the secretory activity of the adrenal cortex, but it returned to pre-radiation levels by 30 minutes. Exposure to doses of 500 R was accompanied by a rapid and temporary stimula-tion of the adrenal cortex and its effect lasted for approximately 60-90 minutes. At doses of 1, 000 R, there was an initial decrease in adrenocortical secretion followed by an appreciable increase within approximately 30-60 minutes after irradiation. However, head X-irradiation with doses of 200-1, 000 R failed to produce a notable increase in the secretory activity of the testis. It is thus suggested that exposure of the head to 500-1, 000 R of X-rays can elicit a rapid and temporary activation of the hypothalamic-pituitary-adrenal axis during the immediate period after irradiation but it does not exhibit any activity in the hypothalamic-pituitary-gonadal axis. -head X-irradiation; adrenal 17-hydroxycorticosteroid secretion; testicular 17-oxosteroid secretion; hypo-thalamic-pituitary-adrenal axis; hypothalamic-pituitary-gonadal axis; dogView full abstractDownload PDF (404K) -
IVIASAO ABE, TOYOAKI AKINO, KIMIYOSHI OHNO1973 Volume 109 Issue 2 Pages 163-172
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe metabolism of lecithin in fetal lung and liver of rabbit was studied in. comparison with adult tissue by incubation of tissue slices with radioactive precursors. The results are summarized as follows: 1. The marked increase of incorporation of 3H-glycerol and 14C-palmitate into lecithin was observed especially in oligoenoic species at 28 days gestation in the lung, indicating the activation of lecithin synthesis via phosphatidic acid pathway. 2. Using 3H-glycerol and 14C-palmitate, ratio of 14C/3H was higher in lecithin than in either phosphatidic acid or diglyceride at all stages examined in the lung but it was not found in the liver. It suggests that a portion of palmitate is incorporated into lecithin or the glycerol moiety in lecithin is partly eliminated by pathways other than phosphatidic acid pathways. 3. The conversion of 3H-palmitate-labeled lysolecithin to lecithin increased rapidly at 28 days gestation in the lung. The isotope ratio of position-2 to position-1 in lecithin was almost unity at all stages in the lung but it was far lower in the liver at the stages other than early gestational one. The high ratio suggests that the reaction is principally operated by acyl-migration of two molecules of lysolecithin.View full abstractDownload PDF (550K) -
HIDEMI YAMAUCHI, KYOJI YAMAMOTO, KENJI KOYAMA, YASUSHI MATSUO, SEIICHI ...1973 Volume 109 Issue 2 Pages 173-187
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSExperimental production of an arterio-venous fistula between the splenic artery and vein of the dog causes increased splenic arterial flow, and reduction of hepatic arterial flow. In the majority of clinical cases of splenomegaly of periportal fibrosis (Banti's syndrome), selective celiac angiography reveals narrowing of the hepatic artery proper, and there is a significant negative correlation between the radii of splenic and hepatic arteries on the x-ray films. The results suggest reduced hepatic arterial flow in such cases. Two different mechanisms are taken into consideration for the explanation of this circulatory condition: There may be some hemodynamical interaction between the portal system and the hepatic artery, or increased blood flow of the splenic artery, or increased blood flow of the splenic artery may reduce the hepatic share of celiac arterial flow. No arteriographical narrowing of the hepatic artery proper was demonstrated in splenomegalic cirrhosis even if high portal inflow is expected through the massive splenomegaly. A comparison of the radius of the hepatic artery proper and the percentage of intrahepatic shunted flow supports the view that the effective portal flow is unchanged in those cases.View full abstractDownload PDF (4121K) -
MAKOTO TAMAI, TETSURO OGAWA1973 Volume 109 Issue 2 Pages 189-200
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSOn the basis of our previous findings in the analysis of collicular field potentials, the interaction between cortico-tectal and retino-tectal inputs was studied at the level of a single neuron in the superior colliculus by electrical stimulation of the ipsilateral optic tract and the visual and adjacent cortex in chloralose-anesthetized cats. 126 extracellularly recorded units were analyzed, 72 units of which were excited only by optic tract stimulation, 25 units were only by cortical stimulation and the remaining 29 units were activated by both ways of stimulation. Remarkable interactions between retino-tectal and cortico-tectal inputs were shown in a considerable fraction of those collicular neurons. Excitation of one pathway leaves mainly suppressive but sometimes facilitatory effects on the other for 150 msec or more. It was found that a part of such suppressive interaction might be accounted for by presynaptic inhibitory mechanism.View full abstractDownload PDF (604K) -
RYOICHI SHIRACHI, HIROYUKI SHIRAISHI, SHIGEHIRO MATSUMOTO, SHINOBU MAT ...1973 Volume 109 Issue 2 Pages 201-202
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSHepatitis B antigen (HB Ag) detectable only by means of rvdioimmnnoassay was found in saliva of 5 out of 36 mentally retarded children in an institution. Electron microscopic study of purified antigen in saliva revealed the presence of tubular and small Dane particles.View full abstractDownload PDF (129K) -
SHIGETOSHI CHIBA, KOROKU HASHIMOTO1973 Volume 109 Issue 2 Pages 203-204
Published: 1973
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe perfusion of the sinus node artery in 9 dogs in situ was performed. The selective injection of aminophylline into the sinus node artery induced a positive chrono-tropic response. The positive chronotropic response to aminophylline was suppressed not only by propranolol but also by tetrodotoxin. It is suggested that the positive chronotropic action of aminophylline is partially due to catecholamine release from adrenergic nerve terminals by excitation of local nerve fibers.View full abstractDownload PDF (103K)
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