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Volume 142 (1984)
- Issue 4 Pages 351-
- Issue 3 Pages 231-
- Issue 2 Pages 119-
- Issue 1 Pages 1-
Volume 142, Issue 2
Displaying 1-14 of 14 articles from this issue
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KAORU SAGISAKA, MINEO IWASA, TSUYOSHI YOKOI1984 Volume 142 Issue 2 Pages 119-123
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSSAGISAKA, K., Iwasa, M. and Yokoi, T. Serological Distinction of A Antigen between Red Blood Cells and Saliva in Blood Grouping of Blood and Body Fluid Stains. Tohoku J. exp. Med., 1984, 142(2), 119-123 - A antigens of red blood cells and body fluids such as saliva, semen and sweat could be serologically distinguished using rabbit or guinea pig immune anti-A. As for antisera specific for red blood cell A, A+ rabbits were intravenously immunized with A group red blood cells. The resulting antisera were absorbed with O and B red cells and with A. Se saliva. The absorbed anti-A reacted with A red cells (titer 1:32) and was not inhibited with A. Se saliva. Guinea pigs were intramuscularly injected with A. Se saliva. Crude antisera contained agglutinins to human red cells which were abolished by absorption with A red cells. After absorption with O. Se saliva, the antisera were proved to have agglutinin activity with A group saliva using latex coated with A. Se saliva. A antigens from blood or body fluid stains could be distinguished by the elution method with these anti-A sera.View full abstractDownload PDF (486K) -
TAKEO MUKADA, JUNICHI KASHIWAGURA, KATSUYOSHI ITASAKA, SHINGO MIYAZAKI ...1984 Volume 142 Issue 2 Pages 125-130
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSMUKADA, T., KASHIWAGURA, J., ITASAKA, K., MIYAZAKI, S., HIRAKAWA, H., SASAKI, Y., ANDOH, S., IGURA, H. and MINETA, T. Giant Hyperplasiogenous Polyp of the Stomach Simulating Malignant Polyp. Tohoku J. exp. Med., 1984, 142 (2), 125-130 - A surgical case of giant hyperplasiogenous polyp of the stomach with unusual radiological and pathological findings is presented. Radiological and endoscopical examinations revealed characteristic papillary (villous) features simulating either true adenoma or malignant polyp of the antrum. Complete serial sections from the resected stomach disclosed no malignant area anywhere in and out of the polyp. The pathomorphological nature and radiological characteristics of this rare lesion are discussed.View full abstractDownload PDF (3220K) -
EIKO ENDO, HIDEE FUJIMOTO, AKIRA ISHIMORI, NOBORU MATSUURA, JUNEJI KHA ...1984 Volume 142 Issue 2 Pages 131-139
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSENDO, E., FUJIMOTO, H., ISHIMORI, A., MATSUURA, N., KHATO, J. and TAKAHASHI, T. In Vitro Test of Phagocytic Ability of Human Platelets Using Colloidal Carbon. Tohoku J. exp. Med., 1984, 142 (2), 131-139-A simple and reproducible test for phagocytic ability of human platelets are described. Platelets obtained from heparinized venous blood were incubated with colloidal carbon (particle diameter=0.11μm) in autologous plasma at 37°C. The number of platelets with or without carbon particles on smear preparations was determined at fixed intervals. Electron microscopic observation confirmed the apparent inclusion of carbon particles in platelets as being an internalization of these particles in the vesicular or canalicular structures. Under optimum conditions, the percentage of phagocytosis-positive platelets in healthy donors was 66.6±14.3 (S.D.)% and the reproducibility of the test was considered to be satisfactory. There was no significant difference between men and women.View full abstractDownload PDF (1461K) -
EIJI INO-OKA, SHOGEN ISOYAMA, YOSHIO SHIMIZU, SHOICHI SATO, KENJI TAMA ...1984 Volume 142 Issue 2 Pages 141-154
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSINO-OKA, E., ISOYAMA, S., SHIMIZU, Y., SATO, S., TAMAKI, K., KITAOKA, S., ISHIDE, N., TAKISHIMA, T., MATSUO, T. and TAKAHASHI, K. A High-Pass Phaseless Filter for Eliminating Low-Frequency ECG Noise during Exercise and Its Clinical Application to Automatic Analysis of the Heart Rate and ST Segment Level. Tohoku J. exp. Med., 1984, 142 (2), 141-154 - We developed a new technique to eliminate low-frequency ECG noise by the use of a specially designed high-pass phaseless filter. The phaseless filter was tested by computer-simulated ECG signals and it proved to be highly effective in eliminating ECG noise without any significant deformation of the ST segment level. The maximum distortion of ST segment level at 0.8Hz cut off frequency of this filter is equivalent to the distortion of the usual ECG Amp having 0.1Hz cut off frequency (JIS). Furthermore, studies of the stabilized ECG recordings during exercise, which became possible by using the phaseless filter, enabled us to develop a method of automatic analysis of the heart rate-ST segment level relationship during and after exercise. The submaximal exercise ECG test was done on 78 ostensibly healthy men. The heart rate (X axis) and three points on the ST segment levels (Y axis) were plotted automatically on an X-Y recorder. Although a great variety of patterns were drawn, we could discern clearly different patterns for normal subject and those with typical ischemic heart disease. Further analysis of this relationship will undoubtedly contribute to the detection of ischemic heart disease.View full abstractDownload PDF (1441K) -
NOBUHIRO KONNO, TORU YAMAUCHI, YASUAKI YAMAGUCHI, MASAAKI FUKUSHIMA1984 Volume 142 Issue 2 Pages 155-163
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSKONNO, N., YAMAUCHI, T., YAMAGUCHI, Y. and FUKUSHIMA, M. Protective Effect of Pretreatment against the Acute Toxicity of Formulated Cyanofenphos in Hens. Tohoku J. exp. Med., 1984, 142 (2), 155-163 Cyanofenphos (Surecide®, O-ethyl O-4-cyanophenyl phenylphosphonothioate) is an organophosphorus pesticide. The protective effect against the near lethal dose, 140% the LD50, of formulated cyanofenphos developed in hens pretreated daily with a small dosage of 1.4% the LD50. The oral LD50 for formulated cyanofenphos was 700mg/kg in the control hens and 1170mg/kg in the hens pretreated with 10mg/kg daily for 8 days. The length of the pretreatment period is important in inducing the protective effect. The protective action against 140% the LD50, 1, 000mg/kg, reached its maximum at approximately 24hr after the last pretreatment. Pretreatment with 20mg/kg daily for 8 days also acted as an antagonist for a challenge dose of 1, 000mg/kg. Three hours after a challenge dose of 400mg/kg, brain acetylcholinesterase (ACNE) activity was 0.14% ΔpH/hr (17.6% of initial value) in hens pretreated with 10mg/kg daily for 8 days and was 0.21 ΔpH/hr (9.1% of initial value) in control hens, the difference being statistically significant (p<0.01). The protective effect of pretreatment against the acute toxicity of formulated cyanofenphos appears to be related to the fact that the formulation produced less inhibition of brain AChE activity in the pretreated hens than in the controls.View full abstractDownload PDF (861K) -
ITARU KIMURA, D.R. AYYAR, SUSAN M. LIPPMANN1984 Volume 142 Issue 2 Pages 165-172
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSKIMURA, I., AYYAR, D.R. and LIPPMANN, S.M. Early Electrodiagnosis of the Ulnar Entrapment Neuropathy at the Elbow. Tohoku J. exp. Med., 1984. 142(2), 165-172 - Reliable, technically not demanding, electrophysiological tests make it possible to diagnose the ulnar entrapment neuropathy at the elbow. Ulnar nerve was stimulated supramaximally at the wrist, below and above the elbow, and in the upper arm, and the sensory nerve action potential (SNAP) and compound muscle action potential (CMAP) were recorded. Sensory and motor nerve conduction velocities (SNCVs, MNCVs) were calculated in each segment. In 12 of 64 symptomatic extremities of 44 patients with a presumptive diagnosis of the ulnar neuropathy at the elbow MNCVs of all segments were within normal limit and only SNCV across the elbow was significantly slowed (p<0.001). In 25 extremities of the patients SNAP was not obtained. Evidence of denervation in the first dorsal interosseous and abductor digiti minimi muscles was detected in about 50% hands tested. This percentage was higher in the hands with absence of SNAP than those with presence of SNAPs. It would appear that measurement of SNCV across the elbow is a more sensitive parameter to detect abnormal conduction across the cubital tunnel in patients with the ulnar neuropathy.View full abstractDownload PDF (666K) -
MASARU MAEBASHI, KAORU YOSHINAGA1984 Volume 142 Issue 2 Pages 173-182
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSMAEBASHI, M. and YOSHINAGA, K. Formation of a Vasopressor Substance in the Incubated Serum in Patients with Various Hypertensive Diseases. Tohoku J. exp. Med., 1984, 142 (2), 173-182 - A vasoactive substance was produced in serum when incubated at 37°C. This substance differed from other known vasoactive agents. It was a phospholipid and caused an elevation in blood pressure by its direct vasoconstriction. This pressor substance increased in the incubated sera of patients with essential hypertension and in spontaneously hypertensive rats. But it was significantly low in humans and dogs in anephric states. These results suggest that the pressor substance participates in the pressor mechanism of essential hypertension and its production is closely related to the kidney.View full abstractDownload PDF (849K) -
KOZO ITO, KENSAKU TESHIMA, HIROSHI SUZUKI, KIICHIRO NODA1984 Volume 142 Issue 2 Pages 183-194
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSITO, K., TESHIMA, K., SUZUKI, H. and NODA, K. A Case of Ovarian Endodermal Sinus Tumor Associated with Pregnancy. Tohoku J. exp. Med., 1984, 142 (2), 183-194 - A case of a 25-year-old 2 gravida, 1 para pregnant woman in the 7th week of gestation who was concurrented with endodermal sinus tumor (EST) is presented. Simple hysterectomy with left salpingo-oophorectomy, wedge resection of the right ovary and omentectomy were done following D & C. Histological features were identical to those described for EST by Teilum. Cytological findings of imprinted smears were characterized by cuboidal or columnar cells with vacuoles, naked-looking cells of various sizes, and cells with an extremely large nucleus/cytoplasm (N/C) ratio. Measurements were made on serum alpha-fetoprotein and immunosuppressive acidic protein. The frequency of malignant ovarian tumors associated with pregnancy in the literature and at our clinic, and the treatment for it were discussed.View full abstractDownload PDF (1876K) -
TATSUO SATO, RYOJI HIRAMATSU, TAISUKE IWAOKA, YUMIKO FUJII, TATSUYA SH ...1984 Volume 142 Issue 2 Pages 195-200
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSSATO, T., HIRAMATSU, R., IWAOKA, T., FUJII, Y., SHIMADA, T. and UMEDA, T. Changes of Platelets, Serum Lactic Dehydrogenase, γ-Glutamyltranspeptidase, Choline Esterase and Creatine Phosphokinase Levels in Patients with Cushing's Syndrome. Tohoku J. exp. Med., 1984, 142 (2), 195-200-In order to identify non-endocrine laboratory tests of diagnostic value in Cushing's syndrome, we measured platelet counts and serum myogenic and hepatic enzyme levels in 10 patients with Cushing's syndrome and compared the findings with those of 15 obese patients without Cushing's syndrome. Patients with Cushing's syndrome had increased numbers of platelets, moderately elevated serum lactic dehydrogenase and γ-glutamyltranspeptidase levels, and significantly lower creatine phosphokinase and choline esterase activities compared with those of obese control patients. We concluded that when several of these abnormal values were seen in obese patients the levels of suspicion for Cushing's syndrome should be high.View full abstractDownload PDF (671K) -
CHIYUKI NAKANOME, MASARU KOIZUMI, HIROSHI FUJIYA, HIROAKI AKAI, TAKAYO ...1984 Volume 142 Issue 2 Pages 201-210
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSNAKANOME, C., KOIZUMI, M., FUJIYA, H., AKAI, H., TOYOTA, T., GOTO, Y., KAMEYAMA, J., MIYAKAWA, K. and HANEW, K. Somatostatinoma Syndrome Accompanied by Overproduction of Pancreatic Polypeptide. Tohoku J. exp. Med., 1984, 142 (2), 201-210 A case of somatostatin and pancreatic polypeptide (PP) producing tumor of the pancreas is presented. A 65-year-old woman was admitted for the evaluation of the tumor in the right upper quadrant of the abdomen. Clinical abnormalities included diabetic glucose intolerance, pancreatic insufficiency and marked dilatation of gallbladder. Marked high concentration of plasma PP and low levels of plasma insulin and glucagon were observed before operation. Plasma insulin concentrations in response to oral glucose tolerance test and arginine infusion were markedly low. A large quantity of somatostatin (4, 300 ng/g ww) as well as PP (1, 340ng/g ww) was detected in the tumor, and somatostatin cells and PP cells were determined by immunofluorescence studies. After operation, pancreatic insufficiency and glucose intolerance were improved, and the patient made a favorable progress.View full abstractDownload PDF (2169K) -
HISAKO OHGAWARA, YUKIMASA HIRATA1984 Volume 142 Issue 2 Pages 211-216
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSOHGAWARA, H. and HIRATA, Y. Islet Cell Surface Antibodies in Diabetes and Their Possible Influence on Glucose Tolerance. Tohoku J. exp. Med., 1984, 142 (2), 211-216 - The prevalence of islet cell surface antibodies (ICSA) in patients with insulin-dependent (IDD), noninsulin-dependent (NIDD) or newly-diagnosed diabetes mellitus was studied. The antibodies were present in 14 (27%) of 15 IDD patients below the age of 30 years, and in 11 (12%) of 91 NIDD patients. Among 46 newly-diagnosed diabetic patients, (aged over 30 years), 14 (30%) were antibody -positive and had a fasting blood sugar exceeding 11mmol glucose. The glucose tolerance after a standardized breakfast decreased in IDD or insulin-treated patients with ICSA compared to patients without antibodies. C-peptide was also lower in patients with circulating ICSA (∑CPR/∑BS during a standardized breakfast test 0.61±0.30 vs. 1.09±0.3 in IDD, 1.18±0.13 vs. 1.46±0.43 in the patients with insulin treatment). These results suggest that circulating ICSA be also present in some newly-diagnosed patients of over 30 years of age who require insulin treatment and who have an associated decreased glucose tolerance and C-peptide response.View full abstractDownload PDF (535K) -
SHIGEFUMI FUJIMURA, TAKASHI KONDO, ATSUSHI YAMAUCHI, MASASHI HANDA, TA ...1984 Volume 142 Issue 2 Pages 217-225
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSFUJIMURA, S., KONDO, T., YAMAUCHI, A., HANDA, M., OKABE, T., SHIONOZAKI, F., SAITO, R., ICHINOSE, T., AKAOGI, E. and NAKADA, T. A Ten-Year Experience with Surgical Resection for Patients with Metastatic Lung Tumors. Tohoku J. exp. Med., 1984, 142(2), 217-225 - Removal of metastatic lung tumor was performed for 27 patients in a period from January, 1972 to December, 1981. They included 22 carcinomas and 5 sarcomas. Diagnosis as having lung metastasis was made after removal of the primary tumor in 18 patients and at the time of the first detection of the primary tumor in 4 patients. In 5 patients the operation for the metastatic tumor preceded that for the primary malignancy. Metastatic tumors were localized in one lobe in 13 patients. Thirteen of the 27 patients underwent lobectomy and 14 received other types of operation, with or without hilar and/or mediastinal lymphnode dissection. Four patients underwent bilateral thoracotomy. Survival rates at 3 and 5 postoperative years of the group of patients who underwent the operation for primary malignancy first were both 49 percent. The number of lesions removed or the type of operation did not seem to have correlations with the survival rate. Patients whose tumor-free interval was more than 40 months tended to survive longer than those who had an interval less than 40 months. The group with a tumor doubling time of more than 50 days showed a higher survival rate than the group with a doubling time of less than 50 days. Of the 4 patients thoracotomized bilaterally 2 are alive for 20 and 34 months postoperatively, while the other 2 died at 20 and 65 months after the operation. In the selected patients with metastatic lung tumors, surgical treatment can be conducted with a reasonably good result, even though the metastatic malignancy is multiple or bilateral.View full abstractDownload PDF (1448K) -
OSAMU NAKAGOMI, TSUNEKO SUZUKI, HAJIME OYAMADA, EIKO KANEDA, YUMIKO SA ...1984 Volume 142 Issue 2 Pages 227-228
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSNAKAGOMI, O., SUZUKI, T., OYAMADA, H., KANEDA, E., SARUTA, Y. and UESUGI, S. Serological Survey of Hepatitis B Virus (HBV) Markers in Out- and In-Patients in a University Hospital. Tohoku J. exp. Med., 1984, 142(2), 227-228 - Of a total of 13, 596 patients and 1, 876 blood donors in a university hospital examined, 550 (4.1%) patients and 31 (1.7%) donors possessed hepatitis B surface antigen (HBsAg) in their blood. The higher incidence of HBsAg in the patient population than in the blood donors verified the view that medical personnel and hospitalized patients are at increased risk of acquiring HBV infection. To assess the actual hazard of the HBsAg-positive patients, we examined hepatitis Be antigen (HBeAg) and its antibody (anti-HBe) status of 228 HBsAg-positive patients and found that 39 (18%) were positive for HBeAg and 168 (74.5%) were positive for anti-HBe. This indicated that only one fifth of the HBsAg-positive patients should be drawn attention in terms of HBV transmission within a hospital.View full abstractDownload PDF (213K) -
NORIKAZU IRIE, RYUICHI NAKAMURA1984 Volume 142 Issue 2 Pages 229-230
Published: 1984
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSIRIE, N. and NAKAMURA, R. Right Hemisphere Dominance in Arousal Induced by Facilitating Positions. Tohoku J. exp. Med., 1984, 142 (2), 229-230-To clarify whether there is left-right difference in arousal induced by position changes, vocal reaction times (RTs) were measured at three different positions of the arms for 10 normal subjects. RTs at the facilitating position of either arm were faster than RTs at the neutral position, and RTs at the facilitating position of the left arm were faster than those of the right. The results indicate that the left facilitating position is more effective for increasing arousal than the right one.View full abstractDownload PDF (187K)
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