New methods for clinical diagnosis of the functional endocrine disorders of the gonadal system inculding the diencephalon, the hypophysis, the gonads and the uterus were devised and clinical cases of endocrine disturbances were evaluated by these methods.
1) Various kinds of methods of laboratory testing of uterus sensitivity to ovarian hormones, i.e. the
32P-uptake test, the oxygen consumption test, the histological examination test, the cervical-mucus-crystallization test, the withdrawalbleeding test, were devised and clinical cases of lowered sensitivity of the uterus to ovarian hormones, detected by these methods, were reported.
2) A new method of evaluating function of the ovary, i.e. the gonadotrophin administration test, was devised by an intravenous administration of gonadotrophin and an estimation of the change of estrogen contents in urine and blood.
3) New methods of evaluating function of diencephalon, i.e. the basal body temperature test and the copper-salt administration test, were devised and applied clinically.
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