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Volume 202 (2004)
- Issue 4 Pages 245-
- Issue 3 Pages 155-
- Issue 2 Pages 69-
- Issue 1 Pages 1-
Volume 202, Issue 4
April
Displaying 1-8 of 8 articles from this issue
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Regular Contributions
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Dong Cao Luong, Naruhiko Ishiwada, Nobue Takeda, Yoichi Kohno2004 Volume 202 Issue 4 Pages 245-254
Published: 2004
Released on J-STAGE: June 23, 2004
JOURNAL FREE ACCESSCapsular serotypes of 122 respiratory Haemophilus influenzae strains were identified utilizing antigenic examinations (Slide Agglutination Test [SAT] and counter immuno-electrophoresis [CIE]), and PCR method. Results of the two methods were compared to find disagreement. Clinical and bacteriological characteristics of encapsulated strains were analyzed. By utilizing PCR assay, 3 (2.5%) serotype b, 1 (0.8%) serotype f and 118 (96.7%) non-typeable strains were found among 122 tested strains. Discrepancy between the results of antigenic examinations and PCR assay was found in one strain. That strain gave positive results by antigenic tests with capsular type c antiserum but it was determined to be capsular type f by PCR. No serotype b− strain was detected. All the encapsulated strains displayed biotype I. All the serotype b strains produced β-lactamase, but none of those was sulbactam/ampicillin and amoxicillin/clavulanic acid resistant. The serotype f strain was β-lactamase non-producing ampicillin susceptible. The patients suffered from respiratory infections due to encapsulated strains displayed safe clinical manifestations and good clinical responses to antibiotic treatments using β-lactams. In pre-vaccination era, PCR is considered to be a useful method for determination of serotypes of respiratory H. influenzae, which may contribute to reducing a possibility of clonal transmission of serotype b strains among children community, which is one of the potential risk factors for pediatric invasive infections.View full abstractDownload PDF (383K) -
Murat Beyzadeoglu, Kaan Oysul, Bahar Dirican, Fikret Arpaci, Arzu Balk ...2004 Volume 202 Issue 4 Pages 255-263
Published: 2004
Released on J-STAGE: June 23, 2004
JOURNAL FREE ACCESSThe aim of this study is to evaluate the incidence of interstitial pneumonitis following fractionated total body irradiation conditioning for bone marrow transplantation with varying lung doses due to shielding technique and different dose-rates. Between 1987 and 2001, a total number of 105 patients have received total body irradiation conditioning for bone marrow transplantation for hematological malignancies at Gulhane Military Medical School. Twelve Gy fractionated total body irradiation was delivered in 6 fractions over 3 consecutive days with Co-60 teletherapy machine. Conditioning therapy included only cyclophosphamide (60 mg/kg/day for two days) and total body irradiation. The median follow-up for patients was 12 months. Interstitial pneumonitis developed in 10 patients out of 105 patients (9.52%). The median total dose to lung was 9.60 Gy (8.88-10.90). The difference between total lung dose and interstitial pneumonitis was not significant. Pneumonitis development in the high dose-rate (>0.04 Gy/min) group versus low dose-rate (≤0.04 Gy/min) group was statistically significant. Low dose-rate fractionated total body irradiation is a reliable conditioning program in bone marrow transplantation with effective lung sparing to avoid interstitial pneumonitis.View full abstractDownload PDF (361K) -
Demet Tok, Gönül Tezcan Keles, Verda Toprak, Ismet Topcu2004 Volume 202 Issue 4 Pages 265-273
Published: 2004
Released on J-STAGE: June 23, 2004
JOURNAL FREE ACCESSThe aim of this study was to evaluate the effectiveness of in-hospital cardiopulmonary resuscitation (CPR) strategies and identify key predictors of post-CPR survival in a university hospital setting. Using a form recommended by the European Resuscitation Council, data regarding in-hospital CPR attempts from January 2001 to December 2002 were recorded and analyzed. The main outcomes of interest were immediate survival after CPR and survival to hospital discharge. Of 307 patients who suffered cardiac arrest in the study period, 103 (33.5%) were resuscitated. Of these 103 patients, 28 (27.2%) survived immediately and 12 (11.7%) survived to hospital discharge. The key predictors of immediate survival were CPR duration and initial cardiac rhythm as monitored by ventricular fibrillation/pulseless ventricular tachycardia (VF/VT). The key predictors of survival to hospital discharge were CPR duration, immediate defibrillation, Glasgow Coma Scale score, and Early Prediction Score. Together, our results suggest that in-hospital CPR strategies require improvement. They also underscore the importance of data collection and analysis in evaluating the effectiveness of in-hospital CPR strategiesView full abstractDownload PDF (316K) -
Masayuki Nara, Kan Sasamori, Sanae Shimura, Hiromasa Ogawa, Satsuki Is ...2004 Volume 202 Issue 4 Pages 275-282
Published: 2004
Released on J-STAGE: June 23, 2004
JOURNAL FREE ACCESSTopical corticosteroid eye drops are commonly used for ocular sarcoidosis. That systemic absorption of corticosteroids by eye drops may influence the clinical course of sarcoidosis may be speculated because it has been reported that the serum concentration of corticosteroids after drop administration was dose-related. To evaluate the effects of corticosteroid eye drops on the clinical course of patients with stage I pulmonary sarcoidosis, we compared the serum levels of angiotensin converting enzyme (ACE) and bilateral hilar lymphadenopathy (BHL) on chest radiographs of group CS, which is consisted of patients who received topical therapy of betamethasone in the form of eye drops for anterior uveitis, and group CN, which is consisted of patients who did not receive any medications throughout the entire course of the disease. Although the serum ACE level was not significantly different between groups CS and CN at the time of the diagnosis of pulmonary sarcoidosis, the level of serum ACE in group CS was significantly higher than that in group CN 20 months after the topical corticosteroid treatment (24 IU/ml and 16 IU/ml, respectively). Further, the size of BHL on chest radiography in group CS was significantly larger than that in group CN 20 months after the topical treatment (82% and 37% of before control, respectively). These findings suggest the possibility that the topical corticosteroid therapy influenced the clinical course of pulmonary sarcoidosis, inducing some delay in the spontaneous remission in the long-term course.View full abstractDownload PDF (247K) -
Nermin Karaturan Yelmen, Gülderen Sahin, Tülin Oruç2004 Volume 202 Issue 4 Pages 283-294
Published: 2004
Released on J-STAGE: June 23, 2004
JOURNAL FREE ACCESSIn anaesthetized dogs (sodium pentobarbitone 30 mg/kg, i.v.) laryngeal vascular resistance was measured by unilateral perfusion at constant flow of the branch of the cranial superior thyroid artery that supplies the larynx. Arterial perfusion was at constant flow and inflow pressure was divided by flow to give laryngeal vascular resistance (RLV). Intraluminal laryngeal pressure (PL) and systemic arterial blood pressure (BP) were also measured. Stimulation (20 V, 20 Hz, 0.2 milliseconds) of the central end of cervical vagus caused an increase in RLV (+22.9±6.1%) and a decrease in PL (−12.1±4.4%). Stimulation (10 V, 10 Hz, 0.2 milliseconds) of the central end of the recurrent laryngeal nerve (RLN) reduced RLV (−3.4±0.8%) and PL (−7.5±4.1%). Stimulation of the peripheral end of the RLN decreased RLV (−7.1±1.9%) and increased PL (+21.6±7.7%). Stimulation of the central end of the superior laryngeal nerve (SLN) increased RLV (+17.9±3.2%) and PL (+59.8±2.7%), whereas stimulation of the peripheral end of the SLN decreased RLV (−4.8±1.6%) and PL (−4.1±2.4%). After treatment with α-adrenoreceptor antagonist phentolamine (0.5 mg/kg, i.v.), stimulation of the central end of cervical vagus nerve reduced RLV by 25% and decreased BP. Phentolamine caused a decrease in BP and reduced the magnitude of increase in RLV in response to stimulation of central end of SLN. After atropine sulphate (0.5-2.0 mg/kg, i.v.), the stimulation of both central and peripheral ends of RLN reduced RLV. The decrease in RLV during stimulation of peripheral end of SLN was reduced by atropine. Thereafter, pancuronium bromide (0.06-0.1 mg/kg, i.v.) was given and dogs were artifically ventilated. After paralyzed, stimulation of the central end of the SLN decreased RLV (+26.0±4.5%) but produced no change in PL. It is concluded that parasympathetic motor fibers in the RLN and SLN are effective for the laryngeal vascularity and non-adrenergic system may be responsible for laryngeal vasoconstriction.View full abstractDownload PDF (406K)
Case Reports
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Murat Acar, Aylin Yucel, Bumin Degirmenci, M. Deniz Yilmaz, Ramazan Al ...2004 Volume 202 Issue 4 Pages 295-297
Published: 2004
Released on J-STAGE: June 23, 2004
JOURNAL FREE ACCESSPneumoceles of the frontal sinus are very rare conditions, characterized by abnormal expansion of the frontal sinus. The patient usually complains of slowly changing facial contours. The etiology and pathogenesis of pneumoceles remains unclear. A case of pneumocele of the frontal sinus is presented, and the differentiated features of the disease are discussed.View full abstractDownload PDF (248K) -
Manabu Shiraki, Sho Takagi, Mika Watanabe, Yuichirou Sato, Seiichi Tak ...2004 Volume 202 Issue 4 Pages 299-304
Published: 2004
Released on J-STAGE: June 23, 2004
JOURNAL FREE ACCESSA 73-year-old male was referred to our hospital for abdominal pain, diarrhea and general fatigue lasting for 3 weeks. Physical examination of the abdomen revealed a firm mass in the left abdominal region. Computed tomography revealed a mass around the descending colon. Colonoscopy and barium enema revealed poor extensibility of the lumen with edematous mucosa, and narrowing of the descending colon with rugged mucosal surface. Because of the clinical symptoms and findings, the patient was diagnosed clinically as suffering from panniculitis of the descending colon. He underwent the left hemi-colectomy with side-to-side colo-colostomy after making of a loop ileostomy. Histological analysis of the resected colon showed an infiltration of inflammatory cells, predominantly lymphocytes, into veins and venules of the submucosa, muscularis propria and fat tissue of the colonic mesentery, with an involvement of all layers of the vessel wall. Arteries were escaped from inflammatory changes. The histopathological diagnosis of enterocolic phlebitis and venulitis was made because of these findings.View full abstractDownload PDF (340K) -
Murat Dede, Güzin Deveci, M. Salih Deveci, Mufit Cemal Yenen, Umi ...2004 Volume 202 Issue 4 Pages 305-310
Published: 2004
Released on J-STAGE: June 23, 2004
JOURNAL FREE ACCESSVilloglandular papillary adenocarcinoma (VPA) of cervix is rare but a well recognized variant of cervical adenocarcinoma with favorable prognosis occurring in younger age group. A 28-year-old white woman, gravida 3, para 2 was admitted for abnormal vaginal bleeding, when she was pregnant at 8th weeks of gestation. Physical examination revealed about 2.5 cm polipoid lesion of the cervix protruding into vagina. Histopathological findings were consistent with cervical VPA. After termination of pregnancy, radical hysterectomy type III was performed. The patient underwent second, third and fourth laparotomies because of recurrent pelvic masses. At the end of five years follow-up period, she died because of the complication of recurrent tumor. VPA is not an innocent tumor, and can be complicated by recurrence and metastasis. More radical surgical and medical attempts should be planned.View full abstractDownload PDF (388K)
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