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Volume 85 (1965)
- Issue 4 Pages 299-
- Issue 3 Pages 201-
- Issue 2 Pages 105-
- Issue 1 Pages 1-
Volume 85, Issue 1
Displaying 1-11 of 11 articles from this issue
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Masahiro Maki, Kazuma Nagasawa, Masataka Nagayama, Kyoko Sasaki1965 Volume 85 Issue 1 Pages 1-11
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAs to the change of factors relating to the plasmin system during pregnancy and puerperium, some conflicts have been found in the literature. This paper deals with the results of systemic analysis of this enzyme system, and the relation be-tween sex hormones and the factors is discussed.
A marked elevation of factors of plasmin system during pregnancy was observed in fibrinogen, spontaneous caseinolytic activity of the euglobulin frac-tion, total plasmin and antiplasmin, but only a slight rise of fibrinolytic and fibrinogenolytic activities of the euglobulin.
The administration of progesterone to human females produced marked increases in total plasmin, antiplasmin and spontaneous fibrinolytic activity of the euglobulin, on the other hand, irregular changes in fibrinogen and spontaneous caseinolytic activity of the euglobulin.
Estrogen administration was responsible for an increase of spontaneous caseinolytic activity of the euglobulin and decreases in antiplasmin and spontaneous fibrinolytic activity of the euglobulin. However, essentially no change in fibrinogen and total plasmin was observed by the estrogen administration.
These findings suggest that the close relation exists between sex hormones and plasmin system.View full abstractDownload PDF (535K) -
Masatoshi Sakka1965 Volume 85 Issue 1 Pages 12-15
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDrs. Miyata and Enomoto reported six cases of leukemia of patients of the breast cancer treated by radiation from 1941 to 1956. Estimated population at risk was 65, 900 man-years. Observed incidence of 6/65, 900 is significantly higher than an expected incidence of 1.56×10-5 man-years for the same period of observation.View full abstractDownload PDF (214K) -
Keiya Tada, Hisao Ito1965 Volume 85 Issue 1 Pages 16-20
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSUrinary indoleacetic acid (IA) has been thought to be derived from the conver-sion of tryptophan to IA through the action of both intestinal bacteria and tissue enzymes. There has been, however, no direct evidence of the In vivo conversion of tryptophan to IA by tissue enzymes. The present studies were made to elucidate this question. Intravenous loading of tryptophan to three children revealed a remarkable increase in IA excretion into urine. Consecutive administration of chloramphenicol resulted in a decrease in IA excretion but was unable to eliminate urinary IA. Increase in IA excretion following oral tryptophan loading during chloramphenicol treatment was found to correspond approximately to that fol-lowing the intravenous tryptophan loading on the same dosis. These results give us a direct evidence of the In vivo conversion of tryptophan to IA by tissue enzymes.View full abstractDownload PDF (246K) -
Akira Nakajima, Takaya Yamamoto, Eisuke Sekiguchi, Seirin So, Yawara Y ...1965 Volume 85 Issue 1 Pages 21-32
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSTo measure the activities of Fe59 and Fe55 in a composite sample a convenient differential counting method have been studied.
Calculating the photo-peak area of 1.10 and 1.29 MeV of gamma rays from Fe59, the minimum countable amount of 3.0×10-4 m. c. c. was obtained without any interference of other activities. The photo-peak was measured by a NaI (TI) crystal scintillation counter and a 256 pulse height analyser.
To measure the Fe55 activity two methods have been tried.
In the first method using a Geiger-Müller counter activities of K-X ray from Fe55 and beta and gamma rays from Fe59 was measured. Subtracting the contribution of Fe59 estimated by the suitable correction rate of beta and gamma rays from Fe59, the amount of Fe55 was deduced. As the counting efficiency of K-X ray is very low, the minimum detectable amount of Fe55 was about 5×10-2 m. c. c.
Instead of Geiger-Müller counter an 1 mm thick NaI (TI) crystal scintillation counter and a 256 pulse height analyser were used in the second method. A typical spectrum of K-X ray was obtained. Subtracting the background and the interference of higher energies the amount of Fe55 was deduced from the photo-peak area of this spectrum. The minimum detectable amount of Fe55 in the second method was found to be less than 1/10 of the minimum detectable amount in the first method.View full abstractDownload PDF (632K) -
Tetsuro Fujiwara, Haruko Hirono, Tsuneo Arakawa1965 Volume 85 Issue 1 Pages 33-39
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe surface-active material, obtained from the foam of calf lungs, contained a high concentration of phospholipids, of which dipalmitoyl-alpha-lecithin being predominant. The phosphatidylethanolamine of the surface-active material con-tained highly unsaturated fatty acids.
Both the composition and fatty acid patterns of the total phospholipid as well as lecithin which were isolated from the surface-active lung foam were found to be similar to those from the lung tissue. This finding indicates that the surface-active material has its origin in the lung parenchyma, most likely in the alveolar epithelium.View full abstractDownload PDF (654K) -
Sunao Kuroda, Hajime Nagamori, Michio Ebe, Misao Sasaki1965 Volume 85 Issue 1 Pages 40-54
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe lungs of 77 infants who were known to be either liveborn or stillborn were histologically observed in order to find morphological characteristics of the lung in both instances. The results of the observation suggest that the expansion of the air-passage as a whole may or may not be the evidence of live-birth. However, localized expansion of the air-passage in the respiratory bronchioli and alveolar ducts was found exclusively in the liveborn infants. The hyaline membrane was also visible only in the liveborn infants.View full abstractDownload PDF (3887K) -
Kazuhiko Fukuda1965 Volume 85 Issue 1 Pages 55-71
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThere were unexpectedly few detailed reports on the family in which more than three members were affected from Wilson's disease. Consequently there are difficulties in the way of studying the genetical aspect of the disease. Four sisters in a family, three cases of typical Wilson's disease and a ease of asymptomatic one, were studied and the results were reported and discussed in this paper. According to the detailed analysis of clinical features, the fairly close similarity that three sisters bear in the age of onset, in the duration of the disease and in the time of beginning, severity or courses of not only chief symptoms but also of some-what atypical symptoms, may be emphasized, though some inconsistencies are inevitable. The pathological studies revealed that not only the typical or basic findings of Wilson's disease, but also relatively rare or somewhat atypical findings were commonly or coincidently found in sister cases. In regard to the copper metabolism, three sisters showed quite the same remarkable disturbances. The genetic fashion of the disease is mostly considered to be of an autosomal recessive pattern, but whether the factor is single or multiple was not yet concluded. Especially in our country the theory of multiple factors has been weighty. However, considering the almost uniformal process of the disease in sister cases and no abnormalities in other family members, it may safely be asserted that the disease is inherited not in multiple factors, but in a single factor. As little attention has been paid to sibling cases, the clinicopathological study of sister cases will contribute to the researches of the genetic aspect of the disease.View full abstractDownload PDF (2707K) -
Jeunichiro Nagasawa1965 Volume 85 Issue 1 Pages 72-82
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe movement of calcium ions in the smooth muscle of guinea-pig taenia coli under various conditions was estimated by means of radioisotope technique. Uptake of 45Ca was not affected by the temperature of the soaking Krebs solution, whereas the rate of efflux of 45Ca decreased considerably in low temperature Krebs solution. Ethylenediamine-tetraacetate (EDTA) increased not only the rate of loss of 45Ca but also influenced markedly the movements of sodium and potassium ions in this tissue; after 30 minutes' incubation in 4mM EDTA-Krebs solution, taenia coli lost about 60m-mole/kg wet wt. potassium and gained 55m-mole/kg wet wt. sodium. Depolarization by high potassium, application of adrenaline, histamine or scrotonin increased the efflux of calcium, but the effect of acetyl-choline was variable dependent on the state of muscle preparation.View full abstractDownload PDF (548K) -
Iwami Tanemura, Shoichi Ito1965 Volume 85 Issue 1 Pages 83-88
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe relative potencies of phenothiazine derivatives to suppress the avoidance responses in the rats which were conditioned in a high degree were determined as follows: promazine 1, chlorpoomazine 0.8, acetylpromazine 1.3, trimeprazine 0.7, levomepromazine 2.9, triflupromazine 3.2, prochlorperazine 3.7, perphenazine 21.4, thioproperazine 35.4, trifluoherazine 39.7 and trifluphenazine 43.8. The dimethylamino derivatives induced the rapid action and its duration was shorter except chlorpromazine and triflupromazine which had a longer lasting effect even with a rapid induction while the piperazine derivatives showed the slow induction and the effect lasted longer as a rule.View full abstractDownload PDF (774K) -
Norio Taira, Yoshiyuki Imazawa, Koiti Motokawa1965 Volume 85 Issue 1 Pages 89-104
Published: February 25, 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSResponses to electrical stimulation of the cat's retina wore recorded from single optic tract fibers. Two kinds of responses, short-latency and long-latency responses were distinguished. The short latency was about 10 msec and the long latency about 30 msec. The type of unit “on” or “off” was determined by local illumination of the center of the receptive field. In the on-unit a short-latency response was obtained at the make of a corneopositive current, but a long-latency one at the break of the current. In the off-unit a current of the opposite direction gave the same result as above. The electrical threshold of the on-unit was generally decreased by steady illumination (facilitation), but that of the off-unit was increased (inhibition) in the initial stage of illumination, but decreased (facilitation) in the later stage. The site of electrical excitation was discussed and it was suggested that the probable seat of electrical stimulation was the synaptic part between the receptor and bipolar cell at least for the on-unit. A more complicated structure was suggested for the off-unit.View full abstractDownload PDF (837K) -
1965 Volume 85 Issue 1 Pages e1
Published: 1965
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (21K)
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