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Volume 125 (1978)
- Issue 4 Pages 305-
- Issue 3 Pages 205-
- Issue 2 Pages 103-
- Issue 1 Pages 1-
Volume 125, Issue 1
Displaying 1-12 of 12 articles from this issue
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EIJI ISHIZAWA, TOGO HORIUCHI, MASAMICHI TADOKORO, YOSHIYUKI OKADA, YAS ...1978 Volume 125 Issue 1 Pages 1-9
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAmong the heart diseases, there are some cases in which pulmonary arteries cannot be visualized by standard right ventriculography and aortography. We have categorized such a case as “angiographically absent pulmonary artery syndrome”, which may include congenital or acquired absent pulmonary artery, and anatomically present but non-visualized pulmonary artery. It has been extremely difficult to achieve an accurate diagnosis in such cases and there has been no report of successful surgical treatment for them. Recently, we developed a method of retrograde pulmonary arteriography, with which the pulmonary artery can be successfully visualized in cases of angiographically absent pulmonary artery. Subsequently, re-establishment of the blood flow to the non-visualized pulmonary artery has been successfully performed in 7 of 8 cases of this syndrome.View full abstractDownload PDF (3080K) -
SINOBU HIGAMI, KIYOSHI OMURA, KOJI NISHIZAWA, TOSHINOBU YAMASHITA, KEI ...1978 Volume 125 Issue 1 Pages 11-17
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSPrenatal diagnosis was successfully accomplished by determining sphingomyelinase activity in the cultured amniotic fluid cells in a case of high risk pregnancy for Niemann-Pick disease (NPD), type A. No detectable activity of sphingomyelinase was found in the cultured amniotic fluid cells obtained at the 17th week of gestation. Patient's pregnancy was terminated and the aborted fetus was proved to be affected with NPD. The liver, brain and skin fibroblasts from the aborted fetus revealed a markedly diminished activity of sphingomyelinase. Sphingomyelin content in the liver of the affected fetus was found to be increased approximately sevenfold as compared with that in a control fetus liver. On the other hand, there was no increase of sphingomyelin in the brain from the affected fetus. No significant increase in cholesterol content was found in the liver and brain from the affected fetus. Electron-microscopic findings revealed membranous cytoplasmic bodies and elec-tron dense material with vacuoles in cytoplasm of the liver cell and a number of Zebra body-like inclusions in the cerebral vessel wall. Biochemical and histological findings of the NPD fetus indicate that there is the progress of the disorder already in the midtrimester of gestation.View full abstractDownload PDF (2009K) -
SENTARO SHISHITO1978 Volume 125 Issue 1 Pages 19-30
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSTo clarify the segmental innervation of the spinal cord to the visceral organs, selective section of the individual spinal nerve root of the dog in different spinal segment was performed, and the distribution of distal degeneration of myelinated nerve fibers in the sympathetic trunk and in peripheral nerves was observed. From the results obtained, much wide-spread innervation of each spinal segment to the visceral organs was revealed, and an efferent system in the dorsal root of the spinal nerve was confirmed to be related to the visceral organ. Furthermore, widely extended innervation of the vagus nerve to the visceral organ was clarified.View full abstractDownload PDF (709K) -
KEIICHI ONO, RYUKICHI HADA1978 Volume 125 Issue 1 Pages 31-38
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIndirect cholangiojejunostomy was carried out using a Latex T tube for pallia-tion of non-curative malignant jaundice and its technique is described. The surgical procedures reported here can separate cholangiojejunostomy which otherwise involves some difficulty into three simple steps; 1) insertion of a Latex T tube into the common bile duct or hepatic duct, 2) Witzel type internal fistulization, and 3) Roux-en-Y jejunostomy. The reported technique can be one of the useful arms for control of obstructive jaundice due to malignancy of the biliary-pancreatic region and may have a special appeal to general practitioners.View full abstractDownload PDF (1076K) -
SHIGETOSHI CHIBA, TOSHIO OHHASHI, TAKEHIKO AZUMA1978 Volume 125 Issue 1 Pages 39-43
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSCanine carotid arteries were isolated, suspended in a bath and perfused under a constant flow rate with arterial blood led from a support dog. Resting perfusion pressure was set at a constant level over 50mm Hg. Drugs were administered into the endothelial side of the artery through a cannulated tubing and the response was obtained as pressure changes. This preparation was proved to be superior to usual isolated arterial strips, since its reactivity was kept in a stable condition over 5-10 hours at 37°C. Using this preparation, effects of 5-hydroxytryptamine (5-HT) on the internal and external carotid arteries were investigated in comparison with effects of norepinephrine. In the internal carotid artery, 5-HT caused a much more potent vasoconstriction than norepinephrine. On the other hand, in the external carotid artery, 5-HT caused only slight vasoconstriction, while norepinephrine produced a marked vasoconstriction.View full abstractDownload PDF (327K) -
KUNIO SUWA, HIROZUMI ASAHARA1978 Volume 125 Issue 1 Pages 45-51
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSVasomotor waves (VMW) were observed in nine cardiac patients during cardiopulmonary bypass. The period and amplitude of the waves were described together with their consistency and other pertinent data. Effects of several pharmacologic agents on these waves were tested. These VMW are likely to be caused by spontaneous oscillation of presso-regulatory feedback systems. Cerebral ischemic response is suspected to be the most likely candidate. However, no patients showed any gross neurological symptoms in the postoperative period.View full abstractDownload PDF (387K) -
YOSHIRO YOSHIDA, MORIKUNI FUKUDA, MOTONAO TANAKA, YOSHIO TERASAWA1978 Volume 125 Issue 1 Pages 53-57
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSTwo-dimensional echocardiography of a patient revealed overriding of the large aortic trunk which bifurcated above the semilunar valve, suggesting persistent truncus arterious. This diagnosis was confirmed by cardiac catheterization and angiocardiography. Surgery and autopsy also confirmed the accuracy of the two dimensional echocardiographic findings. Two-dimensional echocardiography is thus valuable in diagnosing persistent truncus arteriosus.View full abstractDownload PDF (2030K) -
MAKOTO HANAWA, TAKAAKI TAKEBE, SUSUMU TAKAHASHI, MASARU KOIZUMI, KATSU ...1978 Volume 125 Issue 1 Pages 59-69
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn order to study the disposition which is thought to be latent in chronic panereatitis, we investigated the sweat chloride concentration of 95 normal subjects, 43 cases of chronic pancreatitis, 12 cases of cholelithiasis, 15 cases of peptic ulcers, 16 cases of hepatic diseases and 23 cases of diabetes mellitus with the sweat test, using the method of pilocarpine iontophoresis. We obtained the following results. (1) In normal subjects, the sweat chloride concentration was inclined to rise gradually with age from childhood to adulthood; the mean value of sweat chloride concentration was 30.0 mEq/liter in adults from 20 years old, and the upper limit was about 60mEq/liter. (2) The mean value of sweat chloride concentration was 60.0mEq/liter in chronic calcifying pancreatitis; this value was markedly higher than that of control subjects of the same age (p<0. 001). (3) The mean value of sweat chloride concentration in cholelithiasis, peptic ulcer and hepatic diseases did not differ significantly from control subjects. The mean value of sweat chloride concentration in diabetes mellitus was significantly higher than that of control subjects (p<0.01), but was significantly lower than that in chronic pancreatitis (p<0.01). (4) It was supposed that some cases of chronic pancreatitis have a congenital disposition toward abnormal secre-tion of sweat glands and epithelium in the pancreatic duct, resembling cystic fibrosis, and this disposition leads easily to pancreatic disorders when the individual is exposed to various external factors.View full abstractDownload PDF (1118K) -
YASUHIKO HASHIMOTO, TAKESHI SHIMA, SHUH MATSUKAWA, MITSUO SATOU1978 Volume 125 Issue 1 Pages 71-75
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe effect of amikacin on the neuromuscular junction was studied in man during anesthesia and surgery. Amikacin alone did not show any neuromuscular blocking action in normal man in therapeutic doses (100-200mg). However, during recovery from either d-tubocurarine block or phase II block with suceinylcholine, the intravenous administration of 200mg of amikacin caused a decrease in twitch tension. This neuromuscular block aggravated by amikacin was antagonized by edrophonium (10mg) or calcium chloride (400mg). Data obtained from the peroneal nerve-anterior tibial muscle preparation of rabbits suggested that the neuromuscular blocking potency of amikacin was one-twelfth of that of kanamycin in therapeutic doses. Although amikacin is thus less potent than kanamycin, caution should be taken in its use for patients with myasthenic state.View full abstractDownload PDF (727K) -
HIROSHI MUNAKATA, TOKUTARO SATO, ZENSAKU YOSIZAWA1978 Volume 125 Issue 1 Pages 77-83
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSPorcine kidney slices were gently homogenized with 0.9% NaCl in a Waring blender, followed by sieving of the homogenate to isolate tubules. The tubular basement membrane (TBM) was then prepared from the tubules by sonieation in 1.0M NaCl. Electron micrographs indicated a high degree of purity of the TBM with negligible contamination of fibrillar collagen. Analytical data showed that the TBM was a glycoprotein containing approximately 10% of carbohydrates. Of the sugar components, glucose and galactose comprised approximately 70% of the total carbohydrates and glycosylgalactosylhydroxylysine was detected in an alkaline hydrolyzate of the TBM. Besides them, mannose, fucose, glucosamine, galactosamine and sialic acid were also detected. The protein portion of the TBM contained hydroxyproline, hydroxylysine, half cystine, methionine and a large amount of glycine as the characteristic amino acids. Polyacrylamide gel-electrophoresis of the TBM gave 15 bands.View full abstractDownload PDF (1417K) -
SHIGERU MORI1978 Volume 125 Issue 1 Pages 85-91
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThis histomorphometrical study was performed on the kidney and the parathyroid glands of autopsy cases of chronic glomerulonephritis. The kidneys showed atrophy in varying degrees. Weight of the parathyroid glands increased because of proliferation of parenchyma. Weight of parathyroid parenchyma correlated negatively with weight of the kidney and volume density of tubules in renal cortex.View full abstractDownload PDF (1242K) -
TOORU KUDOH1978 Volume 125 Issue 1 Pages 93-101
Published: 1978
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe activity of GM1 β-galactosidase in the brain and liver of patients with GM1-gangliosidosis was assayed using GM1-ganglioside tritiated in the terminal galactose. In the cases of GM1-gangliosidosis Types 1 and 2A the activity was less than 0.5% of the control. In the liver of GM1-gangliosidosis Type 2B the activity was observed to be much higher than that of Types 1 and 2A. On Sephadex G-150 gel filtration, three active fractions (I, II and III) for 4-methylumbelliferyl β-galactopyrancside (4MU) and two active fractions (I and II) for GM1, -ganglioside were obtained in the control liver. There was no active fraction for GM1-ganglioside in spite of the preserved fraction I for 4MU in the liver of GM1-gangliosidosis Type 1 or Type 2A. In any of the three cases fraction II for both 4MU and GM1-ganglioside was not detected.View full abstractDownload PDF (506K)
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