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Volume 115 (1975)
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- Issue 2 Pages 99-
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Volume 115, Issue 1
Displaying 1-14 of 14 articles from this issue
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TAKEO TAKAHASHI, YASUO TSUKAHARA1975 Volume 115 Issue 1 Pages 1-10
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe generalized paroxysmal discharges (GPDs) induced by the visuo-sensory and oculomotor activations in a total of 30 patients were investigated. The patients consisted of 27 epileptics and 3 with sequelae of head trauma; all of them showed photoconvulsive response. The visuo-sensory activation with red-flicker of 15 cycles/sec or with visual stimuli containing patterns, “pattern, ” was carried out under the constant condition of 20 ccl/m2. In 22 cases (73%), G-type (simultaneous occurrence of GPD over all the areas) was induced by red-flicker, while in 28 cases (93%) P-type (GPD was preceded by posterior spikes) was induced by “pattern.” With the oculomotor activation, paroxysmal discharges were induced in 11 cases of photogenic epilepsy; 10 cases (91%) were of A-type (GPD was preceded by anterior spikes), and one case (9%) showed focal spikes over the right frontal area. In 21 cases (70%), the type of GPD changed from G-type to P-type as the red-flicker activation was replaced by the “pattern” activation. Further, in seven (33%) out of the 21 cases it changed from P-type to A-type as the activation with “pattern” was replaced by the oculomotor activation. It was suggested that the non-specific thalamo-cortical system, the visual cortex, and the frontal eye field are chiefly concerned with the occurrences of G-type, P-type, and A-type, respectively, when such stimuli as described above are given independently.View full abstractDownload PDF (686K) -
AIKO TAKASE, ICHIRO MATSUDA1975 Volume 115 Issue 1 Pages 11-13
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSPositive correlation between red blood cell count and serum cholesterol level was found in a case of hereditary spherocytosis associated with nephrotic syndrome. Red blood cell cholesterol content varied with serum cholesterol level.View full abstractDownload PDF (167K) -
TATSUO SATO, KIYOSHI KOBAYASHI, YUKIO MIURA, HISAICHI SAKUMA, KAORU YO ...1975 Volume 115 Issue 1 Pages 15-19
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSPercent of epine-phrine content to total catecholamine is low in pheochromocytomas irrespective of unilateral or bilateral adrenal origin when they have no medullary carcinoma of the thyroid. However, epinephrine content higher than norepinephrine has been noted in the adrenal tumors from the patients with Sipple's syndrome. Although an exact reason for this remained unknown, our data could suggest that the adrenal tumors in Sipple's syndrome are primarily different from other types of pheochromocytoma, and thorough examinations for detecting the thyroid carcinoma should be necessary when the adrenal tumor is rich in epinephrine.View full abstractDownload PDF (296K) -
RIKURO SASAKI, HIROTSUGU YAMAGIWA, SHIZUKA ICHIKAWA, AKIHIKO ITO, SHOI ...1975 Volume 115 Issue 1 Pages 21-31
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSHistometrical estimation of scar tissue was made on 28 hypertrophied human hearts obtained at autopsy in order to know the significance of scar tissue in the process of cardiac hypertrophy and in the development of cardiac failure. Estimation was made on histological specimens of the anterior wall of the left ventricle and the posteromedial papillary muscle, according to Chalkley's point counting method, and the amount of scar tissue was expressed by percentages. The mean percentages were 4.6, 8.5 and 18.3 in the epicardial, endocardial part of the left ventricle, and the papillary muscle. There were very significant differences between these 3 mean percentages. There was a very significant correlation between the percentages of scar tissue in the endocardial part of the left ventricle and heart weight. There were no definite correlations between the percentages of scar tissue in the epicardial part or in the papillary muscle and heart weight. From these results, possible causes of scar formation and significance of scar tissue to the development of cardiac failure were discussed.View full abstractDownload PDF (559K) -
YUTAKA FUKUDA, MICHIO SUGITANI, YONG-GI KIM1975 Volume 115 Issue 1 Pages 33-45
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn the lateral geniculate body (LGB) of urethane-anesthetized and Flaxedil-immobilized rats, unit responses of principal cells (P-cells) were recorded by using flash stimulation of the eyes. By measuring response latencies to electrical stimulation of the optic tract, all P-cells were classified into the fast or slow group according to the criterion established by Fukuda. Flash-evoked unit responses consisted of the two kinds of discharges, i. e. the early discharge (ED) with latencies less than 100 msec and the late discharges of spike burst (LDs) often recurring twice or more (LD1, LD2 and so on). Cells' firings were suppressed during the interval between ED and LD, and those between successive LDs. The ED- and LD1-latencies, measured in dark with strong flashes, were shorter in the fast cells than in the slow ones. The interval between ED and LD1 was shorter in the fast cells than in the slow ones. It was common to the both types of P-cells that as flash intensity was reduced, the ED-latency increased and the LD1-latency decreased. However, the ED-LD1 interval remained shorter in the fast cells than in the slow ones. Upon shifting from dark to light, the LD1-latency markedly increased or decreased in the slow cells, whereas such was not seen in the fast cells. These findings seem to provide a further support for the classification of P-cells into the fast and slow types.View full abstractDownload PDF (751K) -
MICHIO ARAI1975 Volume 115 Issue 1 Pages 47-52
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSMycoplasma colonies were found on culture of synovial fluid in 14 of 18 cases of rheumatoid arthritis. It was possible to demonstrate the colonies in primary culture medium only by the method of hot water fixation and Giemsa staining. The organisms grown on solid medium were also observed electron-microscopically.View full abstractDownload PDF (1750K) -
YOSHIRO WADA, TSUNEO ARAKAWA, NOBUKAZU CHIDA, AKIRA ONUMA, HIROSHI NAK ...1975 Volume 115 Issue 1 Pages 53-59
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA Japanese boy was diagnosed as globoid cell leukody-strophy on the basis of a marked decrease in the galactocerebroside β-galactosidase activity in the leukocytes and the serum when one year and two months old. At autopsy when 1 year and 10 months, microscopic findings were characteristic for those of globoid cell leukodystrophy. Galactocerebroside β-galactosidase activities of leukocytes and sera of his father and mother were found to be half those of control subjects, thus it suggested the parents being heterozygotes of the disease.View full abstractDownload PDF (1478K) -
SHIGETOSHI CHIBA1975 Volume 115 Issue 1 Pages 61-65
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSEffects of glucagon on SA node pacemaker activity and atrial contractility were investigated in isolated canine atrium preparations which were perfused with blood led from a support dog and suspended in a bath. Glucagon at a dose from 0.1 to 10 μg was injected into the sinus node artery, which caused a marked positive chronotropic but a less inotropic effect. The positive inotropic response was simulated by atrial acceleration produced by atrial pacing. Glucagon effects were not influenced by treatment with an adrenergic β-blocking agent, alprenolol or SQ 11725, which blocked effects of norepinephrine. It was concluded that glucagon is more effective on pacemaker activity than on atrial contractile force, and glucagon effects may not be mediated by an adrenergic β-mechanism.View full abstractDownload PDF (315K) -
TADASHI YOSHIDA, GORO KIKUCHI1975 Volume 115 Issue 1 Pages 67-74
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSOccurrence of a biliverdin-iron complex or verdoheme as the final oxidation product of heme moiety in the coupled oxidation of myoglobin and ascorbic acid in air was evidenced and the sequence of heme decomposition in this reaction system was concluded to proceed in the order of protoheme, hydroxy-heme and biliverdin-iron complex or verdoheme. The final oxidation product usually remains attached to globin and appears to give a diffuse absorption possibly with a peak at 760 nm at neutral pH. In alkaline solution the compound exhibits an absorption peak at 840 nm, and when reduced with Na2S2O4, it is readily converted to biliverdin which exhibits a large absorption with a peak originally at 800 nm, being followed by a gradual shift to 760 nm.View full abstractDownload PDF (467K) -
KAZUIE IINUMA, AKIRA ONUMA1975 Volume 115 Issue 1 Pages 75-79
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAn increased slow wave pattern of the EEG basic waves without epileptogenic discharges was observed in an early stage of a case of Krabbe's disease. In the later stage of the illness, spikes and sharp waves were mixed with. The peculiar runs of fast activity which were described by Kliemann et al. (1969) were not observed during the course of our patient.View full abstractDownload PDF (824K) -
SHIGETOSHI CHIBA1975 Volume 115 Issue 1 Pages 81-84
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn blood-perfused isolated canine atrium preparations, single injections of dibutyryl cyclic AMP at a dose range of 1 to 30 mg were made into the cannulated sinus node artery. At doses above 3 mg, dibutyryl cyclic AMP induced a biphasic chronotropic and inotropic response; there was a slight and rapid negative chronotropic and inotropic response, followed by a long-lasting positive chronotropic and inotropic response. The induction of the positive effects was slow, and it took 4 to 8 min to reach a maximum response. These effects continued 20 to 60 min. The ratios of the positive inotropic effects positive chronotropic effect were very similar to those induced by norepinephrine. In this study, it was confirmed that a large dose of dibutyryl cyclic AMP induced a positive chronotropic and inotropic effect on the canine atrium, and the pos-sibility was discussed that cyclic AMP may be involved in the effects of beta-adrenergic amines on the pacemaker and contractile process of the heart.View full abstractDownload PDF (811K) -
TAKASHI TSUBOKAWA, DALE H. RICHARDSON1975 Volume 115 Issue 1 Pages 85-93
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSTwo cases of primary brain tumor composed of an admixture of sarcomatous and gliomatous tissues are reported together with their clinical courses and neurosurgical examination. There is no difference in clinical course nor in the result of examination between the usual glioblastoma multiforme and these admixture tumor. The histological examination at the surgical biopsy and autopsy suggested that neoplastic change of the sarcomatous element occurs markedly on hyperplastic blood vessels in the glioblastoma multiforme. The neoplastic change observed on hyperplastic blood vessels is not affected by radiation therapy.View full abstractDownload PDF (4038K) -
MASAFUMI SHIRAI, SHIRO MITSUKAWA, SHOTARO MATSUDA1975 Volume 115 Issue 1 Pages 95-96
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSEffect of intratesticular pressure was examined on non-motile sperms in the testis whether they move toward the epididymis when it is raised. The head portion of the epididymis of the dog was cut apart at the proximal portion to the testis fully exposing the lumen of the epididymis. The electric stimulation of perivascular nerves of the spermatic cord caused spermatozoa to flow out onto the incision site at 5 min. The number of them increased progressively, almost innumerable at 15 min. These results support the view that the elevated intratesticular pressure by electric stimulation surely works to transfer non-motile sperm in the seminiferous tubules into the epididymis.View full abstractDownload PDF (997K) -
TAI-ICHIRO TAKEMOTO, TSUGUYOSHI SUZUKI, TOMOYO MIYAMA1975 Volume 115 Issue 1 Pages 97-98
Published: 1975
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSUnexpected convulsive attacks were observed in male dd-D mice which were reared for a long-term experiment. After three months from the onset of rearing, some of mice showed convulsive attacks when they were handled in such routine laboratory procedures as weighing, clearing of cage and feeding. The convulsive attack was observed only among the mice being reared individually in each of sections of cage and did not occur in the mice which had been reared as a colony. The incidence rate of convulsive attack increased as the rearing period was prolonged. Our finding was similar to King and coworkers' report (1955) in which convulsions were observed in the singly housed C3H mice. The one thing particular in our observation was the difference of incidence rate according to the extent of isolation, i.e., the higher rate was observed on the condition of mice without other mice in the neighbouring sections than those with neighbouring mate. The neighbouring mate acted some roles to change susceptibility to convulsive attack, even though separated by a sheet of wire-netting.View full abstractDownload PDF (141K)
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