FUKAZAWA, H., SAKURADA, T., YOSHIDA, K., KITAOKA, H., NOMURA, T., SUZUKI, M., KAISE, N., KAISE, K., YAMAMOTO, M., SAITO, S. and YOSHINAGA, K.
Free Thyroxine Estimation for the Screening of Hyper- and Hypothyroidism in an Adult Population. Tohoku J. exp. Med., 1986,
148 (4), 411-420-Serum free thyroxine (FT
4), total T
4 (T
4) and total T
3 (T
3) were determined by radioimmunoassay in 1, 114 adults during a periodic health evaluation to detect unsuspected thyroid dysfunction. As a result, 3 patients with hyperthyroidism, 4 with hypothyroidism, 3 taking thyroid medication, 4 with chronic thyroiditis, 1 with simple goiter and 3 women under estrogen administration were found. Free T
4 values were within the normal limits in the present four subjects taking estrogens, but all of them showed high T
4 and one high T
3 values. FT
4 and T
4 were low in four patients with hypothyroidism, but two of them showed normal T
3 values. For the screening of hyperthyroidism, FT
4 was the most reliable measurement and determination of either FT
4 or T
4 was suitable for the screening of hypothyroidism, but T
3 measurement did not diagnose all patients with hypothyroidism.
View full abstract