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Volume 70 (1959)
- Issue 4 Pages 305-
- Issue 3 Pages 213-
- Issue 2 Pages 103-
- Issue 1 Pages 1-
Volume 70, Issue 4
Displaying 1-12 of 12 articles from this issue
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II. Experimental SupplementIwao Yamaguchi1959 Volume 70 Issue 4 Pages 305-310
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAqueous extracts were prepared from 39 gastric carcinoma tissues and injected into mice intraperitoneally, the liver catalase activity of which was measured. The results obtained are summarized as follows.
1. Liver catalase activities in mice injected with the tumor extracts were significantly lower than those in the control mice.
2. Catalase-lowering activity of a tumor extract was not dependent upon the macroscopic or microscopic features of the tumor.
3. Decrease in liver catalase activity of gastric carcinoma cases had little relation to the catalase lowering activity of the tumor extract, but showed close parallelism with the catalase-depressing ability of the tumor itself calculated under some assumptionsView full abstractDownload PDF (293K) -
Akira Kajita, Katsuhiro Nakamura, Susumu Taya, Teiichi Teshima1959 Volume 70 Issue 4 Pages 311-318
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (3030K) -
Masaaki Inoue1959 Volume 70 Issue 4 Pages 319-323
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn toads the transection or hemisection of the spinal cord was made at the level of the second spinal roots. After 4 days insulin was given. The adrenaline and noradrenaline contents of the adrenal gland were estimated by the permanganate method.
The decrease in the adrenaline content of the adrenal gland causable by insulin hypoglycemia was found to be prevented by the transection of the spinal cord. By the hemisection of the spinal cord it was also abolished in the ipsilateral gland but not in the contralateral gland.
Thus it is concluded that in the toad the descending spinal pathway subserving adrenaline secretion of the adrenal gland does not decussate.View full abstractDownload PDF (229K) -
Kaneyoshi Akazaki, Mizu Kojima, Keigo Miyakawa, Tutomu Watanuki, Terua ...1959 Volume 70 Issue 4 Pages 325-334
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
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Seiichi Zinnouchi1959 Volume 70 Issue 4 Pages 335-340
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSNine dogs, anesthetized with Evipan-sodium, were used in the experiments. The adrenal venous blood was collected by the lumbar route method of Satake et al. and its adrenaline content was estimated chemically by the method of Bloor and Bullen. In dogs, whose splanchnic nerves were cut about 2 hours before the onset of the experiments, the adrenaline secretion rate was increased markedly by the intravenous injection of acetylcholine before administering hexamethonium. After hexamethonium, however, no definite increase in the secretion rate was elicited by acetylcholine.
In dogs, whose splanchnic nerves were cut 2 or 3 weeks before experiments, a considerable increase in the secretion rate was induced by injection of acetylcholine even after administering hexamethonium, although it was smaller than that before hexamethonium.
Thus it may be reasonable to conclude that the suppressive effect of hexamethonium on the adrenal medullary response to acetylcholine is definitely reduced by the chronical denervation of the adrenal gland, but not by the acute denervation.View full abstractDownload PDF (313K) -
Seiichi Zinnouchi1959 Volume 70 Issue 4 Pages 341-345
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSExperiments were performed in eight dogs under Evipan-sodium anesthesia. The adrenal venous blood was collected by the cannula inserted into the adrenal vein according to the method of Satake et al. and was estimated for adrenaline by use of the arseno-molybdic acid method of Bloor and Bullen.
By the injection of carbaminoylcholine in a dose of 0.4mg. per kg. the adrenaline secretion rate of the adrenal gland was markedly increased and was estimated at 0.32-0.65 μg. per kg. per minute in the first 60-second period after the start of injection.
Hexamethonium in doses of 0.50-0.75mg. per kg. was applied and this was followed by the injection of carbaminoylcholine in the same dose as before. At this time, the augmentation of adrenaline secretion was small, 0.01-0.09 μg. being estimated there.
Thus, it may be concluded with definiteness that hexamethonium is capable of reducing the augmented adrenaline secretion of the adrenal gland causable by carbaminoylcholine.View full abstractDownload PDF (269K) -
Takashi Yamaguchi, Masuo Kato, Mitsugi Hanata1959 Volume 70 Issue 4 Pages 347-356
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA method for measuring the volume of the peripheral blood flow by using PAH was reported. The values of the plasma flow per 100 cc. of extracellular fluid in forearm per minute was 8.0-25.3 cc. (mean 15.2 cc.) in 22 normal individuals and 11.9-36.1 cc. (mean 18.3 cc.) in 10 hypertensive, and this method is supposed to be able to be applied clinically for estimating the blood flow in organs or tissues, where the assumption, that the mean concentration of PAH in the extracellular fluid is appro-ximately equal to the PAH concentration in the veins, can exist.View full abstractDownload PDF (485K) -
Report H. Studies on Liver Protein in Surgical Gastric DiseasesToshio Sato, Satoru Akiba, Yoshihiko Miura, Hisanobu Ise, Goro Kakizak ...1959 Volume 70 Issue 4 Pages 357-366
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSBy means of our electrophoretic method applied to analyse the liver protein, as reported in Part I of this series, we studied the liver protein fractions in eight cases of chronic gastritis and 50 cases each of gastric or duodenal ulcer and of gastric cancer. The results obtained were as follows:
1. The liver protein in two cases of chronic gastritis and six of gastric ulcer, but only in mild grade as diagnosed clinically, was found to contain only a very small quantity of albumin (5.8% on the average), the remainder being all globulins, β-globulin being particularly abundant (47.1% on the average).
2. Of the severe cases of gastric diseases, the cases showing the liver protein fraction values within the range of the above mild cases were generally of good general conditions, but those with lowered β-globulin, raised γ globulin and/or albumin value were usually cases with complications or advanced disease.
3. The liver protein fraction values were more frequently within the values of mild cases in gastritis-ulcer cases than in gastric cancer cases, and the β-globulin value was lowered, the γ-globulin and/or the albumin value raised more frequently among the gastric cancer cases.View full abstractDownload PDF (1216K) -
Report III. Studies on Liver Protein in Surgical Biliary Tract DiseasesToshio Sato, Satoru Akiba, Yoshihiko Miura, Hisanobu Ise, Goro Kakizak ...1959 Volume 70 Issue 4 Pages 367-372
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSUsing our method for obtaining electrophoretic patterns of the liver protein, the liver protein fraction in 35 cases of surgical biliary tract diseases was studied. The results obtained were as follows.
1. Among the cases of biliary tract diseases, not to speak of the cases with liver disturbances detected by clinical function tests, even in the cases free from such disturbances and showing good general conditions, lowered β-globulin value and raised i-globulin and/or albumin value in their liver protein could be frequently observed.
2. In comparison with the previously reported cases of gastric diseases, the liver protein fraction picture with lowered β-globulin value and raised γ-globulin and/or albumin value was more frequent among the biliary tract disease cases.View full abstractDownload PDF (1040K) -
Koiti Motokawa, Mitsuo Komatsu, Kei Watanabe1959 Volume 70 Issue 4 Pages 373-382
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe color processes caused by monochromatic lights of equal energy were investigated and expressed in terms of zeta-time curves which indicate the time-course of electrical excitability following a brief illumination.
1. Comparison was made on zeta-time curves obtained at the fovea and at 20° from the fovea.
2. Zeta-time curves for two kinds of white light from sources A and C of the ICI were compared.
3. Curves of direct and indirect induction were investigated at the fovea.View full abstractDownload PDF (448K) -
I. Influence of Diet on Carbohydrate Metabolism in Normal RatsTatuo Saito, Akira Wakui, Akira Ohneda1959 Volume 70 Issue 4 Pages 383-393
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSOne hundred and five normal rats were fed with seven different diets, among which carbohydrate tolerance was found to be decreased extremely in the group fed with high-protein high-fat diet for two months.
Three factors, such as xanthurenic acid, overstrain of Langerhans' islets and pituitary adrenal system were discussed to be presumably responsible for this mechanism.View full abstractDownload PDF (1109K) -
H. The Dietary Influence on the Occurrence of Alloxan Diabetes in RatsTatuo Saito, Akira Wakui, Akira Ohneda1959 Volume 70 Issue 4 Pages 395-401
Published: September 25, 1959
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAlthough almost animals were induced by the administration of 40mg. per kg. body weight of alloxan, occurrence of diabetes mellitus by 30 mg.per kg. body weight of alloxan is the highest in the group of high-protein high-fat high-caloric diet among various dietary groups.
Progress of diabetes by alloxan administration was classified into three groups, namely persistent diabetization, recovery after diabetization and non-diabetization.
Furthermore it was emphasized that glucose tolerance was revealed to be decreased equally in the groups of recovery after diabetization and non-diabetization.
It was suggested that high-protein high-fat diet intensified the induc-tion of diabetes mellitus with the administration of small amount of alloxan and, therefore, could spare the amount of alloxan administered to induce experimental diabetes.View full abstractDownload PDF (231K)
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