All issues
Volume 77 (1962)
- Issue 4 Pages 311-
- Issue 3 Pages 205-
- Issue 2 Pages 99-
- Issue 1 Pages 1-
Volume 77, Issue 1
Displaying 1-10 of 10 articles from this issue
- |<
- <
- 1
- >
- >|
-
Shoichi Yamagata, Yoshinori Sasaki, Akira Ohneda, Nozomu Ito1962 Volume 77 Issue 1 Pages 1-10
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSClinical studies on the endocrine function of the pancreas in diabetes mellitus were performed before and after treatment.
Mean serum insulin activity expressed as glucose uptake of the diaphragm was 0.97 mg. per unit weight of the diaphragm in type I diabetics before treatment, while in type II it was -0.33.
Type I diabetics did not show an increase in serum insulin activity after the dietary treatment, however type II did show an increase.
A significant correlation between serum insulin activity and fasting blood sugar was observed before treatment.
Serum insulin activity after the administration of glucose increases in seven out of twelve cases of type I diabetics and five out of ten cases of type II diabetics. The increase in serum insulin activity, however, was not observed in five out of twelve cases of type I diabetics and five out of ten cases of type II.
The mean levels of plasma glucagon-like activity before treatment were 5.5, 46.8 and 54.0μg. per dl. in normal subjects, type I diabetics and type II diabetics, respectively.
Glucagon-like activity decreased after treatment in both types of diabetics. In several diabetics, whose diabetic state was not improved, it did not decrease.
There was observed a significant correlation between glucagon-like activity in plasma and fasting blood sugar.
The mean ratios of α to β cells in islets of the pancreas were 1:5.59, 1:5.04 and 1:4.03 for non-diabetics, type I diabetics and type II diabetics, respectively.View full abstractDownload PDF (474K) -
Shoichi Yamagata, Jun Uemura, Toshio Otuka, Hiroshi Sasaki, Humiaki Sa ...1962 Volume 77 Issue 1 Pages 11-22
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe fluctuation of the function of the adrenal gland, both cortex and medulla, after treatment was observed in diabetics admitted to our Department.
The average content of 17-OHCS in plasma was within the normal range before treatment and was not changed after treatment in type I diabetics, while it was higher than the normal range before treatment and decreased after treament in type II diabetics.
The average excretions of urinary 17-OHCS before therapy were 7.9 and 10.0 mg. daily in type I and type II diabetics, respectively, whereas after therapy they were 8.1 and 5.2 mg. per day in type I and type II diabetics, respectively. A decreased excretion of urinary 17-OHCS was found especially in type II diabetics when well controlled.
The average excretion of 17-KS in urine was within the normal range before treatment in both types of diabetics. Higher value of urinary excretion of 17-KS was observed in 10 per cent out of thirty type I diabetics and 35 per cent out of fifty-four type II diabetics. After treatment, the average urinary excretions of 17-KS were 7.7 and 7.4 mg. per day, respectively.
The average excretion of uropepsin in type I diabetics before treatment was 273 micrograms per hour, decreasing to 218 micrograms after treatment. It was 388 micrograms in type II diabetics before treatment and markedly decreased to 261 micrograms after therapy.
The eosinophil cells in blood were within the normal range and were markedly reduced in five out of thirty-one type I diabetics and twelve out of thirty type II diabetics before treatment. They decreased only in one out of seven type I and three out of ten type II diabetics after treatment.
The response of eosinophil cells to the administration of ACTH-Z was within the normal range in both diabetic types before and after treatment.
The urinary excretion of adrenaline in diabetics was significantly decreased as compared with the normal subjects. The mean values were 5.5 and 4.7 micrograms daily in type I and type II diabetics, respectively. They remained to be low after treatment, 6.2 and 4.3 micrograms per day in type I and type II diabetics, respectively.
The mean values of urinary noradrenaline excretion in diabetics remained within the normal range before treatment and they did not fluctuate after therapy.
The hyperfunction of the adrenal cortex and a decreased excretion of urinary adrenaline in diabetics were discussed.View full abstractDownload PDF (619K) -
Takeo Sato1962 Volume 77 Issue 1 Pages 23-27
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAn improved assay method of β-glucuronidase activity in bile is described. Fishman's original method was improved in three points.
1) The difficulty in colorimetry due to bile pigment can be avoided by dilution of bile and the use of animal charcoal.
2) The prolongation of incubating time of bile may facilitate the determination of the activity of β-glucuronidase.
3) The use of ethanol after incubation is effective not only to stop the reaction, but also to extract liberated phenolphthalein.View full abstractDownload PDF (156K) -
Report 7. Functional Observation on Neutrophils and Lymphocytes from the Standpoint of the Hematopoietic Phases of the Bone Marrow and the Blood Reaction FieldsAkira Saito1962 Volume 77 Issue 1 Pages 28-41
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (818K) -
Report 8. Functional Observation on Monocytes, Endothel Cells, Eosinophils, Basophils and Plasma Cells from the Standpoint of the Hematopoietic Phases of the Bone Marrow and the Blood Reaction FieldsAkira Saito1962 Volume 77 Issue 1 Pages 42-55
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (744K) -
Report 9. An Analytical Consideration of the Inflammatory Reaction from the Standpoint of the Hematopoietic Phases of the Bone Marrow and the Fields of the Blood ReactionAkira Saito1962 Volume 77 Issue 1 Pages 56-65
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (573K) -
Report 10. Relation between Blood and Tissue Observed from the Standpoint of the Hematopoietic Phases of the Bone Marrow and the Fields of the Blood Defense ReactionAkira Saito1962 Volume 77 Issue 1 Pages 66-77
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (670K) -
Tatsuo Sato, Kaoru Yoshinaga, Nozomu Ishida, Chuichi Itoh, Yasuo Wada1962 Volume 77 Issue 1 Pages 78-82
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA method of screening test for pheochromocytoma and argentaffinoma, which consists of a rapid paper chromatography using NaCl-acetic acid-water as solvent and spraying diazotized p-nitroaniline as color reagent, was described. Using this method, highly specific and accurate results may be obtained within one hour.View full abstractDownload PDF (643K) -
Takeo Sato1962 Volume 77 Issue 1 Pages 83-95
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (464K) -
Takashi Mizuno, Sei-ichiro Sasaki, Toshihiro Okamura, Tsuneo Arakawa1962 Volume 77 Issue 1 Pages 96-97
Published: June 25, 1962
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (85K)
- |<
- <
- 1
- >
- >|