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Volume 79 (1963)
- Issue 4 Pages 335-
- Issue 3 Pages 209-
- Issue 2 Pages 103-
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Volume 79, Issue 4
Displaying 1-7 of 7 articles from this issue
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Ken-ichi Kurouji1963 Volume 79 Issue 4 Pages 335-341
Published: May 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn Clauberg rabbits, the effects of the following plants on the progesteroneinduced endometrial carbonic anhydrase increase were studied: Radix Polygon multiflori, Cortex Acanthopanacis radicis, Herba Epimedii and Semen Cuscutae. All of the plants were administered orally as a water extract.
Progesterone manifested a typical increase in endometrial carbonic anhydrase. Radix Polygon multiflori and Cortex Acanthopanacis radicis administered simultaneously with progesterone suppressed the endometrial response, 0.01-0.1 g. of the former and 10-50 g. of the latter being effective for the inhibition of the effect of 2.0 mg. of progesterone. Herba Epimedii and Semen Cuscvtae did not interfere with the progestational effect of progesterone.View full abstractDownload PDF (396K) -
Fumio Sasabe1963 Volume 79 Issue 4 Pages 342-360
Published: May 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThere have been several reports on experiments which studied histologically the fate of the blood injected to the brain, subdural space and cisterna magna. The author has produced hematoma by injecting red cells labelled with Fe59 in the cerebrospinal space, the brain, subdural and epidural spaces and under the scalp to clarify the dynamics of absorption.
It was found it preliminary experiments that radioactive isotope Fe59 proved to be a very useful tracer to carry out the experiments proper. When it is injected into the ear vein or the cisterna magna of rabbits, Fe59 attached to the red cells leaves the red cells only when they hemolyze, but adheres to new red cells. Most of it becomes distributed in the circulating red cells and hematopoietic tissues and just a small amount of it deposits in the brain. Distribution in the serum and external excretion are also very slight. Deposit in various organs becomes maximum in a short period of time after injection and thereafter maintains a certain value. Fe59 in the circulation only slightly passes into the cerebrospinal space. On the other hand, Fe59 in the cerebrospinal space rapidly passes into the circulation. With increase in amount of intravenous injection of Fe59, higher radioactivities of red cells labelled with Fe59 can be obtained.
Consequently, a large amount of Fe59 was injected into the ear vein of normal rabbits, and blood was withdrawn 3 days afterwards. After serum was separated, it was washed by centrifuge and red cells labelled with Fe59 in normal saline were obtained. After this was injected into the cisterna magna, brain, subdural space, epidural space and under the scalp of normal rabbits to produce hematoma, respectively, the appearance of Fe59 in the circulating red cells, serum, CSF and urine was studied periodically.
In the case of hematoma in the cisterna magna, the passage of Fe59 into the circulation by hemolysis and absorption was fastest, while the deposit in the injected tissues were least. In this case, red cells in the cisterna magna rapidly disappear. This may be due to dilution with the cerebrospinal fluid.
In the case of hematoma in the brain, the passage into circulation due to hemolysis and. absorption was less than that in the case of hematoma in the cisterna magna. The deposit in the injected tissue was smaller than that in the case of hematoma under the scalp and epidural hematoma. Absorption into the circulation through CSF was recognized.
In the case of subdural hematoma, the passage and absorption into the circulation by hemolysis were less fast than those in the cases of hematoma in the cisterna magna and intracerebral hematoma. Deposit in the injected tissues was less than that in hematoma in the cisterna magna. Passage into the cerebrospinal space was recognized. In the case of epidural hematoma, the passage into the circulation by hemolysis and absorption was most delayed, while the deposit in the injected tissues was the most among the intracranial hematomas. In this case, no absorption into the cerebrospinal space was noticed.
In the case of hematoma under the scalp, when compared with various intracranial hematomas, the passage into blood due to hemolysis and absorption was most prolonged, while the deposit into injected tissue was the most. In this case, absorption into the cerebrospinal space was not recognized.View full abstractDownload PDF (1016K) -
V. Plasmin System and Postpartum HemorrhageMasahiro Maki, Kazuma Nagasawa, Toshihiro Sato1963 Volume 79 Issue 4 Pages 361-368
Published: May 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAs to the etiological determination of atone uterine bleeding, the following results were obtained by the measurement of plasmin system.
1. Both caseinolytic and fibrinolytic activity of euglobulin fraction and antitryptic activity of plasma gradually increased during physiological pregnancy and reached a maximum at the time of labor.
2. The plasma of patients with atonic uterine bleeding and patients with hypofibrinogenemia showed significantly elevated caseinolytic activity of euglobuhzi fraction and decreased antitryptic activity.
3. Positive fibrinolysis in plasma was found in 13 of 180 (7.2%) cases of normal and abnormal parturient women, and 5 of these 13 positive cases had atone uterine bleeding.
From the above experiments, we suggest that significant proportion of cases of atonic uterine bleeding includes mild or latent or pre-fibrinogenopenia and the difference between atone uterine bleeding and fibrinogenopenia may be not qualitative but only quantitative.
The term ‘atonic uterine bleeding’ may be applied not only in cases with myoatony but also in those of vasculo-atony and coagWo-aatony.View full abstractDownload PDF (356K) -
Takeshige Yamamoto1963 Volume 79 Issue 4 Pages 369-384
Published: May 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSEffects of high frequency electrical stimulation of the meseneephalic reticular formation upon impulse transmission of the thalamic somatosensory system were studied in unanesthetized dogs under immobilization. As indices of impulse transmission, evoked potentials or unitary activities were recorded from the thalamic ventrobasal complex (VBC) in response to single shock stimulation of the medial lemniscus.
1. The VBC evoked potential recorded focally was a positive-negative diphasic wave of short duration. By examining the recovery cycle and effects of asphyxia, anesthesia and cortical conditioning stimulation, it was evidenced that the positive component of the evoked potential represented ascending impulses of the medial lemniscus and the negative one implied the postsynaptic activity.
2. The negative component of the VBC evoked potential was increased in amplitude for variable lengths of time after high frequency reticular stimulation while the positive component was not influenced. Adequate arousal stimulation applied peripherally showed about the same effect as the reticular stimulation.
3. The enhancement of the negative component of the VBC evoked potential was obtained at about the same threshold of reticular stimulation as for EEG arousal.
4. Concerning the VBC unitary activity, effects of the reticular stimulation were judged by using the following three criteria: latency of evoked spikes, firing index and extent of latency play. It was observed that a half of the VBC units examined was affected more or less by the reticular stimulation, two thirds of them being facilitated and the one third inhibited. Facilitation and inhibition were manifested most frequently in decrease and increase of the spike latency, respectively.View full abstractDownload PDF (3524K) -
Nobukazu Chida1963 Volume 79 Issue 4 Pages 385-388
Published: May 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (200K) -
Yasuo Wada1963 Volume 79 Issue 4 Pages 389-400
Published: May 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA high-voltage paper electrophoretic method of measuring the concentration of doma in urine was described. The recovery rate of doma was 76.0±7.9 per cent and the error of measurement was ±10.6 per cent by this method.
Using this method, it was revealed that the excretion of doma in 24 hours urine amounted to 40_??_150γ in 11 normal subjects, and that it was markedly increased in five cases of pheochromocytoma.
The urinary excretion ratio of eatecholamines and their metabolites by this method in the five cases of pheochromocytoma was always in good agreement with the reported values obtained by measurements using the istope technique.View full abstractDownload PDF (541K) -
Experimental and Clinical ObservationsItaru Ohara, Kenichi Ito1963 Volume 79 Issue 4 Pages 401-413
Published: May 25, 1963
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (690K)
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