The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Volume 175, Issue 3
Displaying 1-7 of 7 articles from this issue
  • HIDETADA SASAKI, KIYOHISA SEKIZAWA, MUTSUO YAMAYA
    1995 Volume 175 Issue 3 Pages 143-162
    Published: 1995
    Released on J-STAGE: August 31, 2006
    JOURNAL FREE ACCESS
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  • YOSHIHIRO ONO, HISAKO YUASA, CHIKAKO OHMA, TOHRU MASHIMO, KEIJI SUZUKI ...
    1995 Volume 175 Issue 3 Pages 163-169
    Published: 1995
    Released on J-STAGE: August 31, 2006
    JOURNAL FREE ACCESS
    ONO, Y., YUASA, H., OHMA, C., MASHIMO, T., SUZUKI, K, and YAMANAKA, H. Eosinophils Infiltration in the Rat Seminal Vesicle Associated with Estradiol-17β- Related Stromal Proliferation. Tohoku J. Exp. Med., 1995, 175 (3), 163-169-We performed a histological quantitative analysis of collagen and smooth muscle in seminal vesicle (SV) stroma after Estradiol-17β (E2) administration to the immature castrated rat. On day 14 after E2 administration, collagen and smooth muscle had increased approximately five and fifteen times, respectively, over the baseline of day 0. On day 28 (14 days after the cessation of E2 administration), smooth muscle decreased to the same level as that on day 7, but collagen did not decrease during the 14 days after the cessation of E2 administration. As the proliferation of stroma, the infiltration of eosinophils was seen in the perigrandular stroma that consisted of rich collagen. The number of infiltrated eosinophils increased exponentially in the period in which collagen proliferated. But in the peripheral stroma which consists of rich smooth muscle, no eosinophil infiltration was seen. These results suggest that eosinophil infiltration into SV is related to E2 administration and to stromal proliferation, especially to collagen proliferation in this condition.
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  • HIROMITSU MAKINO, SHINJI SATO, AKIRA YAJIMA, SHOKO KOMATSU, AKIRA FUKA ...
    1995 Volume 175 Issue 3 Pages 171-178
    Published: 1995
    Released on J-STAGE: August 31, 2006
    JOURNAL FREE ACCESS
    MAKINO, H., SATO, S., YAJIMA, A., KOMATSU, S. and FUKAO, A. Evaluation of the Effectiveness of Cervical Cancer Screening: A Case-Control Study in Miyagi, Japan. Tohoku J. Exp. Med., 1995, 175 (3), 171-178 - To estimate the effectiveness of screening for invasive cervical cancer, a case-control study was performed in Miyagi, Japan. A total of 198 cases (129 mass screen-detected and 69 outpatient-detected) of invasive cervical cancer were identified between 1984 and 1990. The results of the Papanicolaou smear of these cases were compared to those of 396 age- (±5 years) and area-matched controls. Compared with women who had no prior screening (cases 51.6%, controls 16.2%), women who were screened had an odds ratio (OR) for invasive cervical cancer of 0.14 (95% confidence interval [CI] 0.088-0.230). The OR for the 175 cases of squamous cell carcinoma was 0.13 (95% CI 0.077-0.215), while the OR for the 23 cases of screened women with adenocarcinoma was 0.40 (95% CI 0.091-1.753). The time intervals following the last negative smear were assessed and we found an OR for a one-year interval and a two-year interval of 0.09 (95% CI 0.055-0.163) and 0.17 (95% CI 0.083-0.335), respectively. In conclusion, screening for invasive cervical cancer is not only effective but also the degree of protection is high for one to two years.
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  • HIROTAKA KATOH, NOBUHIRO OHKOHCHI, TAKUJI HIRANO, MASATOSHI SAKURADA, ...
    1995 Volume 175 Issue 3 Pages 179-184
    Published: 1995
    Released on J-STAGE: August 31, 2006
    JOURNAL FREE ACCESS
    KATOH, H., OHKOHCHI, N., HIRANO, T., SAKURADA, M., ORII, T., KOYAMADA, N., FUJIMORI, K., TAKEMURA, M., ENDOH, T., SATOMI, S., TAGUCHI, Y. and MORI, S. Viability of Partial Liver Graft from Living Donor in Pigs. Tohoku J. Exp. Med., 1995, 175 (3), 179-184 - For evaluation of the viability of partial liver graft from a living donor, we investigated energy production of mitochondria and radical scavenging enzyme activities in partial and whole liver transplantation in pigs. The values of adenosine triphosphate (ATP) and total adenine nucleotide (TAN) of the partial liver graft were higher than those of the whole liver graft, whereas the hypoxanthine of the partial liver graft was lower than that of the whole liver graft. There was no statistical difference in the radical scavenging enzyme activities between the two groups. The values of respiratory control ratio (RCR) in both groups were above 3.0 and there was no statistical difference. The survival rates of pigs received partial liver and whole liver graft with 2 to 3hr cold preservation was 71% and 91%, respectively and there was no statistical difference between two groups. These results suggest that viabilities of the partial liver graft from the living donor are satisfactory enough, compared with those of whole liver graft from a cadaver.
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  • MICHIYO SAKAMOTO, NATSUME YAZAKI, NORIKO KATSUSHIMA, KATSUMI MIZUTA, H ...
    1995 Volume 175 Issue 3 Pages 185-193
    Published: 1995
    Released on J-STAGE: August 31, 2006
    JOURNAL FREE ACCESS
    SAKAMOTO, M., YAZAKI, N., KATSUSHIMA, N., MIZUTA, K., SUZUKI, H. and NUMAZAKI, Y. Longitudinal Investigation of Epidemiologic Feature of Adenovirus Infections in Acute Respiratory Illnesses among Children in Yamagata, Japan (1986-1991). Tohoku J. Exp. Med., 1995, 175 (3), 185-193 - Using human embryonic fibroblast (HEF) and HEp-2 cell cultures, adenoviruses were isolated from 989 (3.7%) out of 26, 793 pediatic patients with ARI in Yamagata, Japan from January, 1986 to December, 1991. All isolates were identified as types 1 (Ad1)-6 and no other serotypes were identified. Epidemiologic feature was different depending on the subgenus group. Ad1, 2, 5 and 6 (group C) were endemic and the infections occurred frequently in the summer season. Ad3 (group B) was epidemic in the autumn to winter season, although the virus was isolated every month in non-epidemic season. No seasonal distribution of Ad4 (group E) could be determined because the number of patients was limited. Neutralizing antibody positive ratio for group C were more than 40% at 1-2 years of age and almost 100% by 10 years of age but those for Ad3 (group B) were 40% by 10 years of age. The neutralizing antibodies for Ad4 (group E) or Ad7 (group B) became negative by 10 years of age. With group C infections, most cases were infants and young children less than 2 years of age, but Ad3 infections were older children with the peak at 4 and 5 years of age.
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  • KANAE NAKAYAMA, SADAHIKO MASUKO, TOSHIYUKI TSURUTA, TATSUO KUTSUNA, HI ...
    1995 Volume 175 Issue 3 Pages 195-209
    Published: 1995
    Released on J-STAGE: August 31, 2006
    JOURNAL FREE ACCESS
    NAKAYAMA, K., MASUKO, S., TSURUTA, T., KUTSUNA, T. and WATANABE, H. Vascularization and Innervation of the Canine Wrist Joint Synovial Membrane. Tohoku J. Exp. Med., 1995, 175 (3), 195-209 - The correlation between vascular distribution and synovial structures was investigated using corrosion cast of the Synovial fold of the dog antebrachiocarpal joint (wrist joint) under scanning electron microscopy. Arterial branches arose from a main artery deep in the subsynovial layer, ascended toward the free margin of the fold, dividing into several branches, and finally formed a dense capillary network beneath the lining layer. Immunohistochemical study and a retrograde axonal tracing experiment revealed that almost all nerve fibers were associated with the arterial tree and that: (1) proximal parts of the arterial tree were innervated with neuropeptide Y (NPY)-containing noradrenergic sympathetic fibers, vasoactive intestinal peptide- containing non-catecholaminergic sympathetic fibers from the stellate ganglion and substance P (SP)- and calcitonin gene-related peptide (CGRP)-containing sensory fibers from the C7-T1 segments of the dorsal root ganglia; (2) more distal parts of the arterial branches were associated with NPY-immunoreactive sympathetic fibers and SP- and CGRP-immunoreative sensory fibers; and (3) the most peripheral precapillary arterioles were accompanied by only SP- and CGRP-containing sensory fibers. These results indicate that synovial blood flow is regulated by at least three different nerve systems which possess regional differences.
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  • MIKI FUJIMURA, TAKAMASA KAYAMA, TOSHIHIRO KUMABE, TAKASHI YOSHIMOTO
    1995 Volume 175 Issue 3 Pages 211-218
    Published: 1995
    Released on J-STAGE: August 31, 2006
    JOURNAL FREE ACCESS
    FUJIMURA, M., KAYAMA, T., KUMABE, T. and YOSHIMOTO, T. Ganglioglioma in the Basal Ganglia Totally Resected by a Trans-Distal Sylvian Approach. Tohoku J. Exp. Med., 1995, 175 (3), 211-218 - A patient with a ganglioglioma in the basal ganglia is presented. An 18-year-old man presented with involuntary movement in his right hand and right homonymous hemianopsia. Computed tomography and magnetic resonance imaging revealed a cystic tumor with an enhancing nodule in the basal ganglia extending into the thalamus. The mass was totally resected by a tans-distal Sylvian approach and was histologically proven to be a ganglioglioma. This is a rare case of midline ganglioglioma in a patient who underwent gross total resection.
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