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Volume 190 (2000)
- Issue 4 Pages 239-
- Issue 3 Pages 169-
- Issue 2 Pages 65-
- Issue 1 Pages 1-
Volume 190, Issue 1
January
Displaying 1-6 of 6 articles from this issue
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Regular Contributions
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Yosuke Kusano, Yoshisada Shibata, Shigeru Katamine, Taro Yamamoto, Ken ...2000 Volume 190 Issue 1 Pages 1-13
Published: 2000
Released on J-STAGE: May 24, 2005
JOURNAL FREE ACCESSIn order to elucidate demographic and reproductive factors associated with Chlamydia trachomatis seropositivity, serological screening and questionnaire survey were conducted on pregnant women in Nagasaki Prefecture, Japan. Serum samples were taken from 1718 pregnant women between September and December, 1996, at the cooperative obstetric hospitals and clinics, and tested for the presence of antibodies to C. trachomatis using the enzyme immunoassay. A questionnaire was administered on a sub-sample (n=409), among whom 85 (20.8%) were seropositive. A multiple logistic analysis revealed that four characteristics showed a significant association with the seropositivity: (i) experience of premarital pregnancy, (ii) non use of condoms, (iii) short duration of education, and (iv) more frequent induced abortion. The unsafe sexual behavior of young people lacking proper knowledge of how to prevent STD is the most important intervention target for control of the C. trachomatis epidemic in Japan.View full abstractDownload PDF (845K) -
Toshihiro Morito, Kazunori Oishi, Masashi Yamamoto, Keizo Matsumoto2000 Volume 190 Issue 1 Pages 15-22
Published: 2000
Released on J-STAGE: May 24, 2005
JOURNAL FREE ACCESSDipalmitoyl phosphatidylcholine (DPPC) is a major phospholipid constituent in the pulmonary surfactant, whereas lysophosphatidylcholine (Lyso-PC) is a minor constituent, this membrane phospholipid being produced at inflammatory sites in association with activation of phospholipase A2. To determine the role of these two different forms of phospholipids in the phagocytic function of alveolar macrophages (AM), we examined the effects of DPPC or Lyso-PC on Fc-mediated phagocytosis. We demonstrated a significant decrease of the ingestion activity of AM for anti-sheep erythrocyte immunoglobulin G-coated sheep erythrocytes (EA: IgG) by DPPC. On the other hand, Lyso-PC caused significantly increased ingestion of EA: IgG by AM. These data indicate that increase of Lyso-PC due to the hydrolysis of DPPC through activation of phospholipase A2 may up-regulate AM-mediated phagocytic functions in the alveolar milieu associated with infections and inflammation. DPPC may suppress and stabilize the AM-mediated phagocytosis in the normal alveolar environment.View full abstractDownload PDF (461K) -
Masayuki Imaeda, Satoshi Sumi, Satoru Ohba, Kiyoshi Kidouchi, Kyoko Ko ...2000 Volume 190 Issue 1 Pages 23-32
Published: 2000
Released on J-STAGE: May 24, 2005
JOURNAL FREE ACCESSA screening system for pyrimidine metabolism disorders by measurement with high-performance liquid chromatography using dried filter-paper urine samples is presented. This system permits the simultaneous determination of dihydrouracil, uracil, orotic acid and pseudouridine. The coefficient of variations for the four compounds on the filter-paper urine samples were 0.010∼0.069 and the recoveries were 98.5∼107.1%. The detection limits of the four compounds were 2∼20 μmol/liter. The correlation between the filter-paper urine samples and liquid urine samples was excellent (0.938-0.988). We supeculated that this method could be used to detect pyrimidine metabolism disorders, such as dihydropyrimidinuria, dihydropyrimidine dehydrogenase deficiency and hereditary orotic aciduria. As a pilot study, we have analyzed dried filter-paper urine samples from 34 200 healthy Japanese, and found three cases of dihydropyrimidinuria without clinical symptoms.View full abstractDownload PDF (472K) -
Eiji Abe, Kozo Sato, Hajime Murai, Hiroshi Tazawa, Mitsuho Chiba, Koic ...2000 Volume 190 Issue 1 Pages 33-49
Published: 2000
Released on J-STAGE: May 24, 2005
JOURNAL FREE ACCESSEight cases of solitary spinal metastasis with neurological deficit in thoracolumbar spine in which total en bloc spondylectomy (TS) was performed by bisecting the affected vertebra through both pedicles using fine thread wire saws were reviewed. Patient age ranged from 40 to 78 (mean, 62) years. Primary lesions were in the lung (2), kidney (2), thyroid (3) and prostate (1). TS was performed through a posterior approach in 5 cases (T6-7, T12, L2, L2 and L2-3) and through a one-stage anterior and posterior combined approach in the others (L2, L3 and L4). The spine was reconstructed with a ceramic vertebral prosthesis and a pedicle screw fixation system in 5 cases, and with augmented anterior spinal instruments in 3 cases. There were neither surgical complications nor surgical mortality. All patients became ambulatory and pain-free after surgery. Histologically, a marginal surgical margin was achieved in only one case. The other 7 cases had intralesional margin at the osteotomized pedicles. Four patients died from causes unrelated to local recurrence 4 to 44 (mean, 19) months after surgery. Effectiveness of surgery was maintained until death in all 4 of these patients. Asymptomatic local recurrence occurred in 2 patients with renal cancer at 10 and 33 months after surgery. These preliminary results suggest that TS for solitary spinal metastasis can achieve good control of local recurrence without major complications and is clinically acceptable surgery.View full abstractDownload PDF (2611K)
Case Reports
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Takenori Ogawa, Katsuhisa Ikeda, Mika Watanabe, Mitsuaki Satake, Takes ...2000 Volume 190 Issue 1 Pages 51-59
Published: 2000
Released on J-STAGE: May 24, 2005
JOURNAL FREE ACCESSA sinonasal teratocarcinosarcoma (SNTCS) is a rare and aggressive malignant neoplasm histologically characterized by the combination of one or more epithelial elements and mesenchymal components. We report a case of a 78-year-old man with SNTCS involving the nasal cavity and paranasal sinuses. He complained of epiphora and exophthalmos with weight loss. Physical and diagnostic images resulted T4N0M0. The tumor was completely and widely resected via a transfacial approach to perform total maxillectomy with orbital exenteration. The clinical presentation, pathologic features, and clinical course are described with a review of the literature.View full abstractDownload PDF (2385K) -
Yukihiko Fukada, Takehiko Yasumizu, Shoji Ohta, Youko Tsurugi, Kazuhik ...2000 Volume 190 Issue 1 Pages 61-64
Published: 2000
Released on J-STAGE: May 24, 2005
JOURNAL FREE ACCESSA 30-year-old woman was found to be carrying monochorionic-diamniotic twins at 7 weeks of gestation. The growth-retarded fetus died at 21 weeks of gestation. At 28 weeks of gestation, periventricular leukomalacia was detected in the brain of the surviving fetus by transvaginal ultrasonography. A female baby presenting with microcephaly was born at 39 weeks of gestation, and CT of the brain showed microcephaly and marked hydrocephalus. At 12 months of age, the surviving infant presented with severe physical growth retardation, and frequent episodes of clonic convulsions.View full abstractDownload PDF (1038K)
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