The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Volume 55, Issue 1
Displaying 1-20 of 20 articles from this issue
  • Clinical Observations of so-called “Shibi” or “Gatchaki” in Tsugaru District
    Kan-ichi Masuda, Jun-ichi Aoyama
    1951 Volume 55 Issue 1 Pages 1-5
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • Akira Sato
    1951 Volume 55 Issue 1 Pages 6
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • Takeshi Azuma
    1951 Volume 55 Issue 1 Pages 7-21
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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    In the ventral abdominal wall of the 10th month human embryo, the sensory nerve fibres in the subserous layer pass into the non-corpusclar and the corpusclar terminations. The formers are far superior to the latters in quantity and divided into the non-ramified and the ramified endings. The latters are likely divided into the Pacinian bodies and the special ones discovered by me. The Pacinian bodies are found rarely and only in the subserous tissue, but develope almost to the rough completion.
    The special bodies distribute not only in the subserous tissue, but also in other tissues, even much more than the Pacinian bodies, are composed of a good developed inner lulb and a few lamellae surrounding it, and often divide itself into two bodies, to show a twin-like formation. Further-more there is seen as a appendage of this body the formation of a cylinder-body termed the vestibulum corpusculi.
    The inner bulb occupies the half or sometimes nearly the whole part of the body, and consists of many special nuclei and granular and darkreddish stainable substances, showing no cell-border like a syncytium. The vestibulum is composed of the proper substance which contains a few of special nuclei of syncytial nature and the connective tissue capsule. A medullated fibre penetrates the vestivulum after losing its myelin and takes a wavy course in it. Reaching the inner bulb of the proper body, the nerve fibre takes in general suddenly the straight course and end finally with a clubbed termination. But some of the nerve fibres show the change of thickness and the peculiar winding course, and often divide into some branches.
    The muscle-spindles in the abdominal muscles in the 01th month human embryo are composed of a few Weismann's fibres and a thick connective tissue capsule like those in other striated muscles, and found in m. rectus abd. most numerous and well developed. In comparison with the muscle-spindles in the tongue-and the thenar of the same month embryo, the abdominal muscle-spindles may be several times in number and much better developed.
    The nuclei in the Weismann's fibres are divided into the proper nuclei and the special nuclei. The formers are oval and rich in chromatin, while the latters are round and poor in chromatin, and gather in the swelling of the spindle (central nuclei gathering by Felix and etc.). So the swelling formation may be caused, by their gathering. Accordingly, the connective tissue capsule becomes very thin in this place and Weismann's fibres also become so degenerative, that they come in places to disappear incontinously. It seems that the special nuclei might grow from the Schwann's nuclei belonging to the sensory nerve fibres, like the special nuclei in the inner bulb of the terminal body.
    It is not too much to say that the nerve fibres for the muscle-spindle are almost occupied by the sensory fibres, because the motor and the vege-tative fibres are far inferior to the formers. The sensory terminations show the very complicated figures as well as the regular innervation and are divided into the chief and the accessory terminations. A thick medullated fibre for the muscle-spindle loses its medullary sheath and divides into several branches, most of which advance to the nuclei gathering, to ramify furthermore. This is the chief termination. On the contrary, there are a few branches which do not enter the nuclei gathering, but run along the Weismann's fibres forward and terminate finally by encircling them. This is the accessory termination, which is far inferior to the chief termination in scale.
    In the cheif termination, the nerve branches to the nuclei gathering run with their subbranches along the sarcolemm spirally or looplikely, , or often quite irregularly and terminate with each peculiar end-apparatus either epilemmally or hypolemmally. The terminal endings sometimes. remarkably terminate in contact with the special cell nuclei.
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  • Akira Sato
    1951 Volume 55 Issue 1 Pages 22
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • CXLVI. Mucosin Third Report
    Tyuiti Isikawa
    1951 Volume 55 Issue 1 Pages 23-27
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • Hiroshi Wako
    1951 Volume 55 Issue 1 Pages 28
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • CXLVII. Heparin
    Hajime Masamune, Tyuiti Isikawa, Yasuo Katabira
    1951 Volume 55 Issue 1 Pages 29-33
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • Hiroshi Wako
    1951 Volume 55 Issue 1 Pages 34
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • CXLVIII. Structural Study of Group A-specific Carbohydrate from Mucus-Mucin of Pig Stomach Seventh Paper
    Zensaku Yosizawa
    1951 Volume 55 Issue 1 Pages 35-42
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1. A method for estimating free acetylhexosamine or bound acetylhexosamine with bare CI was devised.
    2. An enzyme mixture of snail liver (called ‘the original enzyme solution’) could not split acetyl from N-acetylglucosaminides.
    3. Optimum pH's for α- and β-acetylglucosaminidase in it were found to be 4.5.
    4. β-Acetylglucosaminidase could be separated from α-acetylglucosaminidase by adsorption of the latter to aluminium silicate. A β-acetylglucosaminidase solution, thus prepared, contained also β-galactosidase.
    5. The original enzyme solution as well as the β-acetylglucosaminidase solution above could hydrolyze hardly the group carbohydrate from pig-stomach mucus but comparatively easily a partial-scission product of that carbohydrate with increase of the amount of free acetylglucosamine.
    6. From the findings in 5. a conclusion was drawn that acetylglucosamine molecules in the inner part of the group carbohydrate chain take β-glucosidic type.
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  • CXLIX. Structural Study of Group A Carbohydrate from Mucus-mucin of Pig Stomach Eigth Paper
    Hajime Masamune, Zensaku Yosizawa
    1951 Volume 55 Issue 1 Pages 43-45
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • Akira Sato, Hiroshi Wako
    1951 Volume 55 Issue 1 Pages 46
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • CL. On Chondrosin and Chondroitinsulfuric Acid
    Hajime Masamune, Zensaku Yosizawa, Masahiro Maki
    1951 Volume 55 Issue 1 Pages 47-52
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    N-Acetylchondrosinethylester, and a chondroitinsulfate and its partial cleavage products were allowed to react with HIO4 and the requirements of the oxidizing agent per mole of them and also the production of formalde-hyde from the first one were estimated. The findings thereby and else suggested that 1) chondrosin is chondrosamine-3-β-glucuronide, and 2) chondroitin is expressed by Fig. 3 with acetylchondrosamine at the reducing end of the chain and glucuronic acid at the non-reducing.
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  • (First Report) On the Estimative Observation of Nucleic Acids in Salmonella abortivo-equina
    Hisashi Sato
    1951 Volume 55 Issue 1 Pages 53-59
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • Studies on the Nutrition of Children in Hirosaki Area (9th Report)
    Tsuneo Arakawa, Shigeho Wada, Futsu Takahashi
    1951 Volume 55 Issue 1 Pages 61-68
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • Susm Satoo
    1951 Volume 55 Issue 1 Pages 69-73
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • Itiro Tano
    1951 Volume 55 Issue 1 Pages 75-78
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • Itiro Tano
    1951 Volume 55 Issue 1 Pages 79-80
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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  • I. On the Distribution of Cholinesterase in the Human Brain
    Shigeo Okinaka, Masaki Yoshikawa, Juya Goto
    1951 Volume 55 Issue 1 Pages 81-85
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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    The distribution of ChE in human brains was studied with eight autopsy materials. The concentration of ChE in the white matter of cerebrum is less than one fifth of that in the grey matter of cerebrum.
    Basal ganglions and cortex of cerebellum had larger content of ChE than the grey matter of cerebrum. Putamen and Ncl. caudatus had extraordinarily high concentration of ChE.
    There is some slight variation of the ChE content among the similar portions of these eight brains, but the relationship between the ChE concentration in the brain and the disease of the patients was not clearly observed owing to the small number of test cases.
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  • II. On the Cholinesterase of the Human Serum
    Shigeo Okinaka, Osamu Kitamoto, Masaki Yoshikawa, Juya Goto, Zenyata T ...
    1951 Volume 55 Issue 1 Pages 87-94
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    The serum ChE level in the normal persons and the patients of various disease was determined manometrically. The value was expressed in terms of CO2cmm. per 1 min. per 1 cc. serum freed from the Ringer's solution of 0.015M acetylcholine chloride (Roche).
    1) Average value of serum ChE in normal persons is 65.4. The variation is from 50 to 90.
    2) The serum ChE level in the patients of liver- and neoplastic diseases is low. The decrease of the value is remarkable in the cases of serious damage of the liver and in gastric cancer. The decrease of serum ChE can occur despite the negative results of many liver function tests. The serum ChE level correlates with the results of bromsulfaleine test better than those of other liver function test.
    3) In pulmonary tuberculosis, the variation of the serum ChE level is in a very wide range. Serious cases showed very low value, while in others normal or higher level was found.
    4) In the cases of the endocrine disturbance, nervous disease or other various diseases, no characteristic change of the serum ChE level was found. However, regardless of the sort of disease, the serum ChE level is low in the serious cases.
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  • Satoshi Sato
    1951 Volume 55 Issue 1 Pages 95-104
    Published: December 25, 1951
    Released on J-STAGE: November 28, 2008
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