The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Volume 62, Issue 3
Displaying 1-10 of 10 articles from this issue
  • Shin'itiro Katayama
    1955 Volume 62 Issue 3 Pages 209-220
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    The curve showing the time course of electrical excitability of the eye determined after exposure to colored light and then to white light is mater-ially different from the curve for white light alone, but closely similar to that for the complementary colored light alone. This phenomenon is termed “retinal induction”.
    1. In the present experiment it is shown that direct currents of suitable form and time constant may be used as a substitute for inducing colored light in the experiments of retinal induction.
    2. Condenser discharges; exponentially increasing currents and re-ctangular pulses of various time constants and durations are used, and it is found that the inducing effect is maximal when they are of threshold strength, irrespective of the wave form and time constant.
    3. Condenser discharges of small time constants show an inducing effect equivalent to that of lights of longer wave-lengths, while exponentially increasing currents of large time constants behave like blue light in retinal induction.
    4. When light complementary to the inducing light is interposed between this and the subsequent white light, no retinal induction can be found, and this phenomenon is termed “neutralization of retinal induction.” It is shown that electric stimuli of suitable wave form and time constant can neutralize the retinal induction caused by colored light.
    I am greatly indebted to Prof. K. Motokawa for his kind guidance and helpful criticism.
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  • Takeshi Hoshi, Toru Kojima, Shigenori Kameyama, Kojiro Matsuda
    1955 Volume 62 Issue 3 Pages 221-234
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    In sixteen healthy individuals the effects of alteration of posture on the heart rate were studied by continuous recording of the instantaneous heart rate by means of Carcliotachograph.
    The posture was changed from recumbent to sitting and then standing in one experiment, from squat to standing and then again to squat in an-other experiment.
    Blood pressure was also measured and compared with the change of heart rate.
    On each of the postural change from reclining to sitting and from sitting to standing the heart rate became immediately accelerated, attained its maximum at ten to fifteen seconds, and with oscillatory fluctuations, came to be stabilized within sixty seconds in a level which was always higher than before.
    Similar but more pronounced change was observed in heart rate on changing posture from squat to active standing.
    The physiological mechanisms responsible for these changes were discussed: The immediate effect of changing the posture to more vertical from reclining, is the reduction of venous return to the heart, due to the pooling of blood in dependent parts of the body by gravity. Various cir-culatory reactions or adjustments accompanying the postural change were interpreted on this basis and the importance of the cardio-accelerg ating and vago-pressor reflex originating in the venous area (McDowall and Aviado) was stressed.
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  • Eiki Nanjo
    1955 Volume 62 Issue 3 Pages 235-242
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1. Observations and quantitative analysis of action potentials of respiratory muscles recorded during the conduct of general anesthesia were made. It has been shown that it is possible to judge the depth of anesthesia by watching the pattern of respiratory discharges in the cathode-ray oscilloscope.
    2. Action potentials of the intercostal muscles during the applica-tion of several different methods of positive pressure respirtion were observed. A method of positive pressure, applied as respiratory assistance, which is thought to be most physiological from the electromyographic view-point and from the viewpoint of blood gas determination, is recommended.
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  • Takashi Yamaguchi, Yasuhiko Hino
    1955 Volume 62 Issue 3 Pages 243-251
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • Its Application to Enlargement Radiography (Studies on Enlargement Radiography. 1st Report)
    Shinji Takahashi, Kihachiro Komiyama, Masamichi Tanaka
    1955 Volume 62 Issue 3 Pages 253-259
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    This paper is concerned with our very fine focus of a fixed anode tube applied to the enlargement radiography. The focal spot of 0.126mm. in size, acertained under the geometrical and experimental consideration, was made by electron beams narrowed after the principle of bias phenomena. By means of this very fine focus method any part of the body can be taken in sharp enlargement radiogram. Roentgenographic conditions are de-tailed. Up to now, 930 times exposures were made with this bias tube with no ruin on the surface of the target.
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  • Part I
    Genyo Mitarai
    1955 Volume 62 Issue 3 Pages 261-270
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    The electric response of the optic lobe to retinal stimulation by light was observed in the isolated brain-eyeball-preparation of toad.
    1. The response consisted of two or three main waves which are first negative monophasic or first diphasic with initial positive abrupt and a series of successive monophasic waves. But these wave forms showed remarkably seasonal variations. In a hibernation toad the response con-sisted of only two or three large waves.
    2. Such complicated waves as seen in summer toads are simplified by repetitive stimulation of a certain frequency into only two or three waves.
    3. Strychnine facilitates the activity, especially that of the elements which respond in the beginning.
    4. According to these findings, it appears that two or three main waves show the activities of the afferent terminals while a series of suc-cessive waves show the activities of the synaptic process and motor cells.
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  • Part II
    Genyo Mitarai
    1955 Volume 62 Issue 3 Pages 271-281
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1. The latency of on-response was changed markedly by the changes of stimulus intensities, especially by the changes from 0.1 lux to 6 lux, and showed a large seasonal variation. The amplitude was changed in pro-portion to the log-intensity at least within a range from 0.1 lux to 1 lux, in winter toads.
    2. The optic lobe off-responses were frequently absent even if on-responses appeared. The latency of the former was always shorter than that of the latter. But wave forms were almost the same in both cases. The optic lobe off-response seems to arise from the off-elements in the optic lobe, which receives neural impulses originated in the retina as post-inhibitory-rebounds.
    3. From comparison of the latency and culmination time of optic lobe response with those of optic nerve and retinal responses the following relation was established: The latency of retinal b-wave ≤ the latency of optic nerve response < the latency of optic lobe response < the culmina-tion time of retinal b-wave. The latency of the retinal b-wave correspond-ed to 60 to 70% of that of optic lobe response. Accordingly it seems that the retinal process plays a dominant role in the change of latency of the visual process. These findings also suggest that the b-wave originats from the immediate precursor which sends the' impulse to the optic nerve.
    4. The latency of optic lobe on-response in the course of dark adapta-tion showed a characteristic change which resembled the critical stage in the so-called perception time for light. These findings suggest that the evoked potential of the optic lobe is closely connected with the occurrence of the visual sensation and can be an objective measure for visual activity.
    The author wishes to express his gratitude to Dr. Seizo Katsunuma and Hideo Toyoshima for their constant interest and guidance during this study, and to Mr. Koichi Otani for his invaluable technical assistance.
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  • Shoichiro Ohara
    1955 Volume 62 Issue 3 Pages 283-286
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • M. T. Peng, H. C. Lee, H. S. Lin
    1955 Volume 62 Issue 3 Pages 287-297
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1. Extract of psidium guajava root induced sex organ atrophy in male rats and diestrus in the female by subcutaneous injection. Growth retardation, adrenal hypertrophy, thymus involution and local necrosis were observed also.
    2. No remarkable change was found in the orally administered rats.
    3. Vacuolated basophils were found in the anterior pituitaries of the injected rats, especially many in the male.
    4. Oestrous cycle of mice was inhibited by oral administration. of large amount of psidium extract. Slight decrease of the weight of the prostate with seminal vesicles was observed in male young mice but it is not statistically significant.
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  • C. Chang, M. T. Peng
    1955 Volume 62 Issue 3 Pages 299-302
    Published: October 25, 1955
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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