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Volume 66 (1957)
- Issue 3-4 Pages 205-
- Issue 2 Pages 107-
- Issue 1 Pages 1-
Volume 66, Issue 2
Displaying 1-11 of 11 articles from this issue
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Masuzo Oba1957 Volume 66 Issue 2 Pages 107-114
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
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Special Reference to the Possibility of Differentiation of Two Types of Diabetes Mellitus and of Differentiation of Nondiabetics from Diabetics by Sugar Loading TestYoshio Goto, Kogo Seino, Isao Ito1957 Volume 66 Issue 2 Pages 115-124
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe standard sugar loading test (50g. of glucose) was performed in normal adults, non-diabetic patients, and diabetic patients. Our critieria for normal sugar loading test are: a fasting blood sugar below 120mg.%, a peak level below 200mg.%, a 2 hour level below 120mg.% for capillary blood, and a negative urine sugar. In diabetic patients, evaluation of the loading curve may indicate whether insulin is needed in the treatment schedule. If the fasting blood sugar is below 195mg.%, the 2 hour value below 280mg.%, and the peak level below 332mg.%, his diabetic symptoms can be controlled without insulin injections; on the contrary, if the fasting blood sugar is above 218mg.%, the 2 hour value above 298mg.%, and the peak level above 348mg.%, insulin must be used in addition to dietary treatment. The interpretation of transitional and equivocal sugar loading curves and the definition of renal glycdsuria were also discussed.View full abstractDownload PDF (569K) -
Yoshio Goto, Kogo Seino, Isao Ito1957 Volume 66 Issue 2 Pages 125-130
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe limiting level of hyperglycemia was determined by a 2-dose glucose tolerance technique in 46 diabetic and 15 non-diabetic individuals. In most cases, the 2-dose technique revealed the maximum level of blood sugar which could be attained by oral ingestion of glucose. This, by difinition, is the limiting level of hyperglycemia. A remarkably constant ratio existed between the fasting blood sugar value and the limiting level of hyperglycemia. In both severe and in mild diabetics, as well as in non-diabetics, the ratio of limiting level of hyperglycemia to fasting blood sugar levels fell within the range of 1.6 to 2.3 in 90% of cases.View full abstractDownload PDF (327K) -
Kozo Watanabe1957 Volume 66 Issue 2 Pages 131-143
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
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Tatuzi Suzuki, Kazukuni Yamashita, Takaaki Mitamura1957 Volume 66 Issue 2 Pages 144
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
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Sixth Paper: Pentosenucleic AcidHajime Masamune, Hirosi Yosizaki1957 Volume 66 Issue 2 Pages 145-152
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Pentosenucleic acid was prepared from human placentas in electrophoretically homogeneous state. Prep. I was contaminated only with less than 5% DNA, but Prep. II with more than 30% DNA. They were investigated not only chemically but in biological connection with pregnancy-toxemia.
2. Prep. II caused histological lesions in liver and kidney and elevated blood pressure, when injected intravenously into pregnant rabbits. It also prolonged the time of absorbing a blister produced by subcutaneous injection of physiological saline in pregnant rabbits. Prep. I showed tendency of giving the positive skin reaction for pregnancy and cancer.
3. Placental PNA must be a strong factor inducing pregnancy toxemia like placental proteins of which Yosizaki will inform later on.3)View full abstractDownload PDF (844K) -
Part I. Stimulation with Constant CurrentKazumi Yamagiwa1957 Volume 66 Issue 2 Pages 153-162
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Standing on a theoretical ground, excitation was distinguished from initiation of impulse.
2. Regarding the initiation of impulse as due to simultaneous excitation of a certain length L in less than D (duration of excitation), a theoretical treatment was developed on various phenomena of excitation. Chief phenomena explained were, a) appearance of Ir (rheobase for initiation of impulse) combined with a proper duration, tr, and b) repetitive responses without rise of threshold.
3. Discussions were made on a) existence of L, b) strength-duration-relation in initiation of impulse, c) Ir, ir, tr and τ (chronaxie), and 4) repetitive responses.View full abstractDownload PDF (520K) -
Part. II. Stimulation with Slowly Rising and Alternating CurrentsKazumi Yamagiwa1957 Volume 66 Issue 2 Pages 163-174
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. It was shown that the following four facts can be the case without accommodation:
a) Appearance of a liminal gradient Pr in stimulation with linearly rising current.
b) Linear relationship between final current and time constant in stimulation with exponentially increasing current.
c) Repetitive responses to linearly rising current.
d) Intensity minimum or frequency optimum in stimulation with alternating current.
2. Lapicque's “soeul de climalyse” was explained.
3. Discussions were made on: a) identity of βr and I∞-γ-line, b) independence of β'r and I∞-γ-line from accommodation, c) meaning of βr, and d) modes of action of slowly rising currents as stimuli for initiation of impulse.View full abstractDownload PDF (516K) -
Part III. AccommodationKazumi Yamagiwa1957 Volume 66 Issue 2 Pages 175-185
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
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Koiti Motokawa, Tadashi Aizawa1957 Volume 66 Issue 2 Pages 187-196
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSRetinal processes in two typical achromats were investigated. by the method of electrostimulation. From measurements of time courses of electrical excitability of the eye following a brief illumination, two kinds of process were distinguished.
1. The time courses of the two processes showed no dependence on wavelengths of lights, and their magnitudes varied like the scotopic visibility curve, as the wavelengths of spectral lights were varied. Therefore they were interpreted as subserving achromatic vision.
2. The spatial distribution of both processes was found very similar to that of the density of rods in the retina.
3. The two processes differed, however, with respect to intensity ranges of illumination which elicits them ; the working range of the one process was from 10-6 to 104 millilamberts, and that of the other from 10-6 to 102, when tested with a flash of white light lasting 40 msec.
4. Dark-adaptation curves were obtained from the achromats. They showed two parts like a normal dark-adaptation curve. These two parts were accounted for in terms of the two kinds of achromatic process studied above.View full abstractDownload PDF (484K) -
Kazukuni Yamashita1957 Volume 66 Issue 2 Pages 197-203
Published: August 25, 1957
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn dogs anesthetized with evipan-sodium, the adrenal venous blood specimens were collected through the lumbar route preparation. The adrenaline content of the specimens was measured colorimetrically by means of the Bloor & Bullen's arseno-molybdic acid method. The blood sugar content was also determined simultaneously.
Insulin was applied intravenously in a dose of 7 units per kg. of body weight. The adrenaline secretion rate was increased gradually, and from 1 to 2 hours after insulin a definite increase was invariably observed. At the height of augmentation of adrenaline secretion, hexamethonium was injected intravenously in a dose of 0.75mg. per kg. In all cases the secretion rates were cut down to low levels by hexamethonium. It was mea-sured in 3 cases as 0.02-0.04 μg. per kg. per minute after hexametho-nium against 0.13-0.30 μg. before hexamethonium. In one case, it was 0.01 μg. against 0.07 μg.
Thus it is concluded that hexamethonium acts to inhibit the accelerating adrenaline secretion causable by insulin hypoglycemia.
It is my pleasure to acknowledge the encouragement and advice I have received from Prof. T. Suzuki. I am also grateful to Dr. I. Tanaka for his help given in each of my experiments.View full abstractDownload PDF (358K)
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