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Volume 93 (1967)
- Issue 4 Pages 301-
- Issue 3 Pages 199-
- Issue 2 Pages 105-
- Issue 1 Pages 1-
Volume 93, Issue 3
Displaying 1-10 of 10 articles from this issue
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Kenji Koyama1967 Volume 93 Issue 3 Pages 199-217
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSBy means of a dye dilution method using Indoevanine green as an indicator, measurements of splenic blood flow and circulation time were carried out on the control and ischemic spleens in the dog and on spleens of clinical cases of Banti's syndrome with fairly satisfactory results. Splenic blood volume, vascular resistance and O2 consumption were calculated from the splenic blood flow and circulation time. The results are summarized as follows: Blood flow of the ischemic spleen of the dog was found increased, as compared with the control. In human subjects, total splenic blood flow of the control cases was approximately 300ml/min, while it was markedly increased in all the cases of Banti's syndrome. Splenie blood flow per gram tissue, however, was decreased in this syndrome. Concerning the splenic blood volume, resistance and circulation time, there were obvious differences between the control and diseased spleens. Total O2 consump-tion of the Banti spleen was three to six times greater than that of the control. Oxygen consumption per gram tissue, however, was markedly decreased. It was concluded that the splenic tissue in Banti's syndrome was in a hypoxic state, which might play a role in the pathogenesis of this syndrome.View full abstractDownload PDF (2801K) -
Takashi Nakamura, Shozo Nakamura, Noboru Karoji, Tatsuya Aikawa, Osamu ...1967 Volume 93 Issue 3 Pages 219-226
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe influence of alcoholic intake on hepatic function was investigated in two groups of apparently healthy workmen. In laborers at a fish market, there was no significant difference of hepatic function tests between those with and without the habit of high alcohol intake. The dietary surveys showed rather increased protein intake in the heavy drinkers. As it is conceivable that these results are associated with the particular condition of the fish market laborers who can eat a lot of fish, a further investigation was carried out with employees engaged in sedentary works at an electric power company. Though abnormal bromsul-phalein test was generally high in its incidence in this group of workers and the results were not so clear-cut as in the former group, the incidence of abnormal bromsulphalein test was similar or only slightly higher in the heavy drinkers as compared with non-heavy drinkers or abstainers. Protein intake was not decreased in the heavy drinkers. Thus, the results of hepatic function tests in heavy drinkers in these worker groups are quite different from those in heavy drinkers visiting the hospital. This difference is explained by the absence of protein deficiency in the heavy drinkers of the worker groups. From these results, the critical quantity of alcohol to cause hepatic injury is discussed.View full abstractDownload PDF (371K) -
Takashi Nakamura, Shozo Nakamura, Atsushi Onodera, Osamu Suzuki, Tatsu ...1967 Volume 93 Issue 3 Pages 227-233
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThirty-two rats were divided into 4 groups and were fed on four kinds of liquid diets for 3 weeks. The first group was fed on a control diet similar to the average Japanese diet. The second group was kept on a similar diet except that sucrose was replaced isocalorically with alcohol up to 36% of toatl calories. Twelve mg of choline chloride per day were given to the first and the second groups. The third group was fed on a low protein choline-deficient diet. The diet of the fourth group was identical with that of the third group except that sucrose was replaced isocalorically by alcohol up to 36% of total calories.
Total hepatic lipids were found to be 53.8mg/g in the first group, 99.2mg/g in the second, 88.9mg/g in the third and 190.3mg/g in the fourth. Hepatic triglycerides were 8.2mg/g in the first group, 38.8mg/g in the second, 30.1mg/g in the third and 102.6mg/g in the fourth. Histological examination also showed the same tendency. Thus, a large amount of alcohol itself produces fatty liver, and associated dietary deficiency further accelerates its development.View full abstractDownload PDF (1246K) -
Naoshi Nakamura1967 Volume 93 Issue 3 Pages 235-247
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSCalcium carbonate gallstones and calculus-like concrements of calcium carbonate experimentally produced by Maki et al. were cut into thin serial sections by the author's resin-reinforcing technique.1 These specimens were then observed under polarized light, by contact microradioeraphy or after various histochemical stainings. The results obtained were as follows: a) Human calcium carbonate gallstone has a specific structure of its own, though it has been considered until now to be an amorphous mass. b) In human calcium carbonate gallstone, mucopolysaccharides were found evenly distributed, filling the spaces among calcium carbonate crystals in reticular fashion. c) Histochemically, these mucopolysaccharides consisted mainly of sulfated mucopolysaccharides with some contamination of neutral or weakly acid mucopolysaccharides. d) The mucopolysaccharides in human calcium carbonate gallstone are quite similar to sodium alginate in an artificial calculus in their way of distribution and arrangement in minute details. These facts suggest that mucopolysaccharides may take an important part through their bridging action in the formation of calcium carbonate gallstones.View full abstractDownload PDF (2704K) -
Itsuo Yamaura, Shiko Chichibu1967 Volume 93 Issue 3 Pages 249-259
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Super-high frequency electric field (100μW/mm3;11Gc) was applied to the abdominal ganglia of crayfish and prawn.
2. Changes of the spontaneous discharge frequencies were used as an index of response, and they were divided into two phases.
3. During the irradiation, the discharge frequency decreased. This was called suppressed phase.
4. After termination of the irradiation, the discharge frequency increased up to 40% over the control value. This was designated as supernormal phase.
5. A fifty percent attenuation of the intensity of the applied electric field produced twice as much elongation of the time constant of the declining limb in the suppressed phase.
6. Repeated irradiation produced an accumulative effect.
7. Possible mechanisms of the microwave irradiation were discussed with relation to the thermal conversion of absorbed energy and the re-orientation effect of cell membrane structure.View full abstractDownload PDF (948K) -
Itsuo Yamaura, Shiko Chichibu1967 Volume 93 Issue 3 Pages 261-267
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA simple electronic device to discriminate amplitudes of action potentials was described. The principle of the impulse amplitude discrimination circuit (IADC) was to use the time lag in the falling phase of the action potential and the application of NOT-AND gate in the circuit. An application of IADC to the analysis of spontaneous discharges from the crayfish abdominal ganglion, and the detec-tion of microwave effect was presented.View full abstractDownload PDF (316K) -
Kitsuya Iwama, Ichiji Sumitomo1967 Volume 93 Issue 3 Pages 269-277
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSSpontaneous unitary discharges were recorded from the lateral geniculate body in anesthetized rats. Measurements were made on the number of dis-charges in successive time intervals of unit length. With the neurons in which the stationary distribution of the discharge number was found to obey the Poisson law the joint distribution of the discharge numbers of two successive time intervals was studied. The stochastic model of Smoluchowski which fits to density fluctuation of a colloidal solution was found to be applicable to interval-to-interval fluctuation of the discharge number.View full abstractDownload PDF (414K) -
Yasuharu Sakai1967 Volume 93 Issue 3 Pages 279-284
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSUrine of cats was collected before and after medullo-adrenalectomy and was analyzed fluorimetrically for adrenaline and noradrenaline. Bilateral medullo-adrenalectomy was performed in two stages under sodium pentobarbital anesthesia. Urinary excretions of adrenaline and noradrenaline were not changed by unilateral medullo-adrenalectomy. After bilateral medullo-adrenalectomy, the excretion of adrenaline was reduced markedly, whereas that of noradrenaline was not changed. These results indicate that adrenaline excreted in urine is derived mainly from the adrenal medulla and, in part, from the other sources, while noradrenaline in urine comes mainly from extra-adrenal origins, presumably the endings of adrenergic nerve fibers.View full abstractDownload PDF (262K) -
Yasuharu Sakai1967 Volume 93 Issue 3 Pages 285-289
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSRemoval of the adrenal medulla in cats was performed in two stages under sodium pentobarbital anesthesia. One mg eserine per kg of body weight was in-jected subcutaneously before and after medullo-adrenalectomy. Urine of 24-hour period was collected before and after injection of eserine and fluorimetrically analyzed for adrenaline and noradrenaline. The urinary excretion of adrenaline was increased significantly after administration of eserine in both intact and medullo-adrenalectomized cats. However, the urinary excretion of adrenaline in response to eserine in medullo-adrenalectomized cats was only 8 per cent of that in intact cats. The urinary excretion of noradrenaline was also increased after injection of eserine. As to the magnitude of increase in noradrenaline excretion there was no definite difference between those before and after medullo-adrenalec-tomy.View full abstractDownload PDF (240K) -
Shoichi Kasahara, Leonard E. Reisman1967 Volume 93 Issue 3 Pages 291-300
Published: 1967
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA case is described of a girl with developmental retardation and facial anoma-lies.
A cytological abnormality was found consisting of a deletion of the short arm of one of the E chromosomes, which on the basis of morphologic and autoradiographic studies have been identified as a number 18 chromosome.
Autopsy findings included aplasia of the corpus callosum of the brain, congenital deformities of the cranial bones and of the chest.
The clinical and anatomical findings in 14 previously reported cases are dis-cussed.View full abstractDownload PDF (1868K)
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