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Volume 176 (1995)
- Issue 4 Pages 191-
- Issue 3 Pages 131-
- Issue 2 Pages 69-
- Issue 1 Pages 1-
Volume 176, Issue 3
Displaying 1-8 of 8 articles from this issue
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NAOYOSHI TAKATSUKA, NORITO KAWAKAMI, ATSUKO OHWAKI, YOSHINORI ITO, YOK ...1995 Volume 176 Issue 3 Pages 131-135
Published: 1995
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSTAKATSUKA, N., KAWAKAMI, N., OHWAKI, A., ITO, Y., MATSUSHITA, Y., IDO, M. and SHIMIZU, H. Frequent Hard Physical Activity Lowered Serum β-Carotene Level in a Population Study of a Rural City of Japan. Tohoku J. Exp. Med., 1995, 176 (3), 131-135-To determine the effect of physical activity on serum β-carotene, we analyzed data about life styles including 3-day food records and blood samples collected from 57 men and 74 women in a rural city of Japan. Physical activity was asked as mean frequency of hard physical activities per week last year. A declining trend in serum β-carotene was observed with increasing frequency of hard physical activities in men. In multiple regression analyses, the frequency of hard physical activities showed a negative partial correlation coefficient (r=-0.38, p=0.007) with serum β-carotene in men when controlled b yage, BMI (body mass index), dietary factors (carotene intake, alcohol consumption and vitamin supplements use), smoking status, serum total cholesterol and serum triglycerides. These results suggest that frequent hard physical activity decreases serum β-carotene especially in men.View full abstractDownload PDF (514K) -
SEIKI ITO, AKIO USAMI, MASATOSHI YAMAZAKI, AKIRA SHIBATA1995 Volume 176 Issue 3 Pages 137-147
Published: 1995
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSITO, S., USAMI, A., YAMAZAKI, M, and SHIBATA, A. A Radioimmunometric Assay for Urinary α2-Macroglobulin. Tohoku J. Exp. Med., 1995, 176 (3), 137-147-To measure urinary α2-macroglobulin levels, a sensitive radioimmunometric assay was established. The least detectable level of this assay was 225pg/ml. A linear correlation between α2-macroglobulin levels and serial dilution of urine samples was found. Western blot analysis and study on column chromatography revealed that the molecular weight of α2-macroglobulin in urine was identical to that of serum α2-macroglobulin. The findings suggested that urinary substance detected by the present assay was truly α2-macroglobulin. Timed overnight urine samples from 49 diabetic patients with retinopathy and 20 healthy controls were measured by the present assay. Patients were classified as Albustix-negative and Albustix-positive patients. The highest urinary α2-macroglobulin excretion rates (α2-MER) was found in Albustix-positive patients followed by Albustix-negative patients and the healthy controls. In view of the fact that the stroke radius of α2-macroglobulin (88Å) is larger than that of the restrictive pore (56Å), the present finding suggests that leakage of α2-macroglobulin in urine may be induced by defect of non-discriminatory pores in the glomerular basement membrane proposed by Deen and colleagues.View full abstractDownload PDF (1331K) -
RYOETSU ABE, SHIGEMI OOISHI, KAZUTO SATO, HIROSHI SUMA, TSUNEMICHI WAK ...1995 Volume 176 Issue 3 Pages 149-154
Published: 1995
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSABE, R., OOISHI, S., SATO, K., SUMA, H., WAKABAYASHI, T., SAWATANI, S. and TAKEUCHI, H. Development of an Apparatus to Measure Plasma Colloid Osmotic Pressure Mounted on the Extracorporeal Hemodialysis Circuit. Tohoku J. Exp. Med., 1995, 176 (3), 149-154-We newly developed an apparatus to measure colloid osmotic pressure (COP) of blood plasma continuously by hemodialysis (HD) or extracorporeal ultrafiltration method (ECUM) without any invasive procedure or blood sampling. The COP value measured by this apparatus highly correlated with the COP value calculated from the concentration of total protein of blood plasma (TP) sampled simultaneously (y=21.182+0.96256x, r2=0.911). Measurement of the COP with this apparatus seems to be reliable.View full abstractDownload PDF (443K) -
HIDESHI TOMITA, KAZUO IKEDA, KAZUKI IIDA, SHUNZO CHIBA1995 Volume 176 Issue 3 Pages 155-162
Published: 1995
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSTOMITA, H., IKEDA, K., IIDA, K. and CHIBA, S. Mild to Moderate Pulmonary Valvular Stenosis in Infant Sometimes Improves to the Condition Unnecessary to Do PTPV: Doppler Echocardiographic Observation. Tohoku J. Exp. Med., 1995, 176 (3), 155-162-The purpose of this study is to clarify the natural history of the valvular pulmonary Stenosis (PS) from the standpoint of the indication for percutaneous transvenous pulmonary valvuloplasty (PTPV). We retrospectively analyzed age-dependent changes of the peak velocity in the pulmonary artery (peak V) using Doppler echocardiography (Doppler), and some other echocardiographic and clinical findings in 55 children with mild to moderate PS. Groups A, B, and C consisted of those who had peak V above 3.54m/sec, between 3.54 and 2.74m/sec, and less than 2.74m/sec, respectively. Peak V of 42 patients who had the first Doppler study before 1 year of age decreased from 2.61±0.66 to 2.27±0. 80m/sec (p<0.01). One infant in group A, that initially included 3 children, has improved to group B. Among the 15 patients in group B, one patient deteriorated to group A, and peak V of 10 infants reduced to less than 2.74m/sec. In group C, peak V of 2 infants increased above 2.74m/sec. Other than age at the first examination, we could not find specific indications that could predict the reduction of peak V. Mild to moderate PS younger than 1 year of age sometimes markedly improves; the invasive procedure of PTPV may not be necessary in non-critical infant patients with mild to moderate PS.View full abstractDownload PDF (927K) -
KENJI SUDO, KENJI KONNO, TOMOYUKI YOKOTA, SHIRO SHIGETA1995 Volume 176 Issue 3 Pages 163-171
Published: 1995
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSSUDO, K., KONNO, K., YOKOTA, T. and SHIGETA, S. A Screening System for Antiviral Compounds against Herpes Simplex Virus Type 1 Using the MTT Method with L929 Cells. Tohoku J. Exp. Med., 1995, 176 (3), 163-171-We developed the improved MTT assay system for in vitro evaluation of anti-HSV-1 agents using L929 cells derived from mouse connective tissue. This assay system provides results in 4 days using a 96-well microplate. The EC50 values of several anti-HSV agents (ACV, BVaraU, and others) were found to be similar to those obtained by the plaque reduction method using MRC-5 cells. The present MTT assay is rapid, accurate, and may be useful as an automatic screening system for evaluation of anti-HSV-1 compounds.View full abstractDownload PDF (825K) -
SATORU ISHIBASHI, KENJI NAMIKI, MOTOI ABE, YASUHIRO SHIRAHATA, KEISUKE ...1995 Volume 176 Issue 3 Pages 173-180
Published: 1995
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSISHIBASHI, S., NAMIKI, K., ABE, M., SHIRAHATA, Y., OHNISHI, K., TOYODA, T. and OHUCHI, K. Cystic Adventitial Disease of the Popliteal Artery-A Case of Young Boy. Tohoku J. Exp. Med., 1995, 176 (3), 173-180-Cystic adventitial disease (CAD) of the popliteal artery (PA) is rare but one of the well-recognized causes of intermittent claudication. Now more than 200 case reports are available in the world, but there are only 6 cases younger than 15 years old. In this paper, we report a case of 14-year-old boy with CAD of the PA found by intermittent claudication. On examination, the pulses were not palpable below the right popliteal artery, and the angiography demonstrated about 1.5 cm-long obstruction of the right PA. We operated a resection of a cyst with artery, and replaced the autovein graft (V. saphena magna). Cyst contained mucoid degeneration-like ganglion. Two weeks after operation, the angiography showed no stenotic lesion, and follow-up at 4 years showed no symptoms.View full abstractDownload PDF (1543K) -
AKIRA KOBAYASHI, FUJIHIKO NISHINOMIYA, YUHZOU FUKAMACHI, MASAHIRO OHTA ...1995 Volume 176 Issue 3 Pages 181-185
Published: 1995
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSKOBAYASHI, A., NISHINOMIYA F., FUKAMACHI, Y., OHTAKA, M., YAMAMOTO, J., TAKAGI, K., TANAKA, S., TAKIZAWA, S., IMADACHI, H., FUKASE, M., SHIHIZU, Y. and HAYASAKA, K. A Case of Glycogen Storage Disease Type III (Glycogen Debranching Enzyme Deficiency) with Liver Cirrhosis and Hypertrophic Cardiomyopathy. Tohoku J. Exp. Med., 1995, 176 (3), 181-185-We present a 26-year-old woman with glycogen storage disease type III (debranching enzyme deficiency) complicated with liver cirrhosis and hypertrophic Cardiomyopathy. Glycogen debranching enzyme has two catalytic sites, oligo-1, 4, -1, 4-glucantransferase (EC 2.4.1.25) and amylo-1, 6-glucosidase (EC 3.2.1.33). Variability in the clinical phenotype could be a function of the involvement of one or other catalytic site, or differences in tissue expression of the defective enzyme, or both. We hypothesize that some subtypes of glycogen storage disease (GSD) type III may cause liver cirrhosis as seen in GSD type IV due to the accumulation of glycogen of abnormal structure.View full abstractDownload PDF (909K) -
NORIHIKO NATORI1995 Volume 176 Issue 3 Pages 187-190
Published: 1995
Released on J-STAGE: August 31, 2006
JOURNAL FREE ACCESSNATORI, N. A Case of Cutaneous Anthrax. Tohoku J. Exp. Med., 1995, 176 (3), 187-190-A 63-year-old man developed black crusts on the parietal scalp that showed mixed infections of dermatophytes and Bacillus anthracis on culture. The lesions improved with bifonazole, griseofulvin and bacampicillin hydrochl oride. Although cutaneous anthrax is now a very rare disease, the mortality is high in untreated cases. If a patient has black crusts, anthrax should be differentiated firstly.View full abstractDownload PDF (1386K)
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