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Volume 97 (1969)
- Issue 4 Pages 289-
- Issue 3 Pages 191-
- Issue 2 Pages 101-
- Issue 1 Pages 1-
Volume 97, Issue 2
Displaying 1-9 of 9 articles from this issue
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Toyoharu Isawa, Koichiro Shiraishi, Koichi Okubo, Takashi Matsuda, Sut ...1969 Volume 97 Issue 2 Pages 101-112
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSPostural effects on regional ventilation were studied in nine normal subjects using radioactive xenon gas. Two scintillation detectors were mounted on two precordial spots on the right and left lungs, and regional ventilation was assessed on the same spots in the supine position and the right and left lateral decubitus positions.
Regional total lung capacity (TLCr) and regional turn-over rate increased in the dependent lung in the lateral decubitus positions, whereas regional functional residual capacity (FRCr) decreased in the dependent lungs. Regional 50% wash-out time was always shorter in the dependent lung than that in the superior lung, although there was no appreciable difference in the right and left lungs in the supine position.View full abstractDownload PDF (647K) -
Masahiro Maki, Kazuma Nagasawa, Atsushi Urushihata, Yoshihiro Ogawa, K ...1969 Volume 97 Issue 2 Pages 113-118
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn 2 cases of postoperative acute renal failure, abnormally high level of plasminogen, low fibrinolytic activity of euglobulin fraction and decreased urokinase excretion into urine were observed.
These changes may be explained by the following mechanisms:
(1) Tissue activator of plasminogen from the kidney (urokinase) enters into the circulation and also is excreted into urine in normal condition.
(2) The production of urokinase might be suppressed markedly under such a condition as acute renal failure. This would be the cause of lowered urokinase level in both blood and urine. The lowered level of plasminogen activator in blood may cause an accumulation of plasminogen, because continuous conversion of plasminogen to plasmin is disturbed.
From the above consideration, we have reached the conclusion that the kidney may play an important role as a regulator of circulating plasminogen.View full abstractDownload PDF (345K) -
A. Elmo Saito, Mineko Fukushima1969 Volume 97 Issue 2 Pages 119-139
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDownload PDF (1342K) -
Toshio Fujita, Masao Miyazaki1969 Volume 97 Issue 2 Pages 141-154
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIntravenous regional anesthesia was re-evaluated, and the rational use of this technic was discussed.
In five healthy medical students lidocaine anesthesia was examined for the onset, recovery time, analgesia with sustained motor activity or the effect of dif-ferential block, safety dose and optimal concentration of lidocaine. Using our own mechanogram, the twitch responses of the left finger and E. M. G. of the hypothenar group evoked by an electrostimulator were recorded on the monitor oscilloscope.
By Holmes' technic, analgesia followed by anesthesia was produced with 3mg/kg of 0.5% lidocaine solution. Volitional movement of volunteers' fingers were sustained up to ten minutes after the infusion of lidocaine but in this research twitch responses scarcely continued for 30 minutes when the tourniquet was released. During the process of this regional block, the phenomena of ‘post-tetanic facilitation’ were observed.
It is still uncertain that this kind of nerve block belongs to ‘non-depolarizing block’ or ‘mixed block’ at the neuromuscular junction. Anyway, exsanguination of the arm to be anesthetized is quite essential for this technic. Venous blood gas analysis at the time of tourniquet release revealed the effect of ‘ischemia’ or ‘exsanguination’. From the data of pyruvate/lactate ratio, venous pCO2, and base excess, oxygen deficit was assumed in association with the progress of anaerobic metabolism. This study was performed for only half an hour and the results of analysis do not indicate harmful effect of the treatment for human subjects. Our experiment also suggests that man can tolerate almost without danger the present anesthetic procedure.View full abstractDownload PDF (4847K) -
Masahiro Maki, Kyoko Tachita, Yasuyuki Kawasaki, Kazuma Nagasawa1969 Volume 97 Issue 2 Pages 155-160
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSFrom the view-point that amniotic fluid embolism is associated with disseminated intravascular coagulation, platelet thrombi or both, heparin therapy was attempted on a patient with suspected amniotic fluid embolism. The treatment was effective.
The tests for coagulation-fibrinolysis system revealed a sudden and transient prolongation of thrombin clotting time and prothrombin time, and decrease in fibrinogen and platelets during shock. These laboratory findings assured that acute disseminated intravascular coagulation was complicated in this patient. The significance of erythrocyte sedimentation rate in establishing the diagnosis of obstetric hypofibrinogenemia was emphasized.View full abstractDownload PDF (376K) -
Toshio Sato, Kenji Koyama, Yasuo Suda, Kenichi Watanabe1969 Volume 97 Issue 2 Pages 161-174
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSSplenoportography obtained from 71 patients with idiopathic splenomegaly (so-called Banti's syndrome) was examined in relation to the portal pressure and the extent of extrahepatic shunt. It was noted that in patients with increased portal pressure, collateral channels were visualized; the splenic vein was curved or tortuous; the sum of the length of the splenie vein and that of the portal trunk was increased; the junction of the splenic vein with the portal vein was shifted to the right; and visualization of intrahepatic branches of the portal vein was impaired. It is therefore possible from the findings in splenoportography to estimate the degree of portal hypertension.
Hepatofugal collateral channels consisted most often of ascending channels through the both right and left gastric veins and the esophageal vein. In the majority of patients in whom ascending collateral channels were demonstrated in splenoportography, esophageal varices were detected in x-ray films with barium meal. Extrahepatic shunt measured with RISA was correlated well with the extent of collateral channels in splenoportography and proved to be useful in quantitative evaluation of collateral circulation.View full abstractDownload PDF (3131K) -
Kazukuni Yamashita, Keishun Nakasone, Kunihiko Kawao1969 Volume 97 Issue 2 Pages 175-180
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe effect of methylenedianiline on testicular 17-oxosteroid secretion caused by pregnant mare serum (PMS) was evaluated by measurements of 17-oxosteroids in the spermatic vein blood of the dog. Testicular 17-oxosteroid secretion in dogs which received a single injection of PMS (2, 000 per animal) into the saphenous vein increased markedly and reached the maximum within approximately 90 minutes after the injection; the increase in secretion tended to be maintain-ed over 4 hours of observation. At the highest rate of secretion, an intravenous injection of methylenedianiline (20 or 60mg/kg) into these dogs brought about a rapid decline in the output of testicular 17-oxosteroids. The response was rever-sible. These results show that methylenedianiline can prevent the augmented secretion of testicular 17-oxosteroids caused by pregnant mare serum.View full abstractDownload PDF (369K) -
Sakuzi Kodama1969 Volume 97 Issue 2 Pages 181-185
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA method of measuring the oxygen consumption of a rabbit-heart perfused in vitro is described. The quantity of the consumption is simply measured by a burette system at any time during the perfusion experiment.View full abstractDownload PDF (254K) -
Shigetoshi Chiba, Kazubiro Ohkuda, Koroku Hashimoto1969 Volume 97 Issue 2 Pages 187-189
Published: 1969
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe perfusion of the AV node artery in dog heart in vivo was performed. After destroying the sinoatrial node by selective injection of ethanol into the sinus node artery, the selective administration of catecholamines into the AV node artery induced acceleration of nodal rhythm. In the course of recovery, eminent oscillatory change in the AV nodal rhythm was regularly observed. This oscillatory change was not blocked by atropine, phenoxybenzamine and tetrodotoxin.
These results led to the conclusion that the oscillatory response of the AV node to cateeholamines might be probably an inherent property of AV node pacemaker itself.View full abstractDownload PDF (141K)
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