The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Volume 39, Issue 1
Displaying 1-7 of 7 articles from this issue
  • Kimio Maruta
    1940 Volume 39 Issue 1 Pages 1-10
    Published: September 30, 1940
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • 96th Report. The Difference of Urinary Elimination of Phenolsulphonphthalein (Injected Intravenously) in Rabbits with Different Liver Power; and Influence of Yakriton upon It. Part I
    Fumio Ohta
    1940 Volume 39 Issue 1 Pages 11-25
    Published: September 30, 1940
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    1. If phenolsulphon-phthalein is injected intra-venously, the total amount of it excreted in the urine will be almost the same in all the rabbits, despite the strength of liver power, but the rate of the dye elimination will be greater in a rabbit with strong liver power than in one with weak liver power (Cf. Tables 2, 3 and 4, and Fig. 1).
    2. Yakriton, the detoxicating hormone of the liver, will accelerate the rate of elimination of phenolsulphonphthalein in the urine in a rabbit with weak liver power (Cf. Tables 2 and 5, and Fig. 2).
    3. The influence brought out by yakriton upon the rate of urinary elimination of phenolsulphonphthalein will be larger in a rabbit with weak liver power than in a rabbit with strong liver power (Cf. Tables 3 and 6, and Fig. 3).
    In the present paper the kidneys were not injured, so that rabbits excreted the whole amount of the dye as duly expected. Using yakriton, the elimination was accelerated, but the total amount of the dye excreted through the kidneys was not changed. Yakriton exerted its accelerating influence through the liver upon the kidneys.
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  • 97th Report. The Difference of Urinary Elimination of Phenolsulphonphthalein (Injected Intravenously) in Rabbits with Different Liver Power; and Influence of Yakriton upon It. Part 2
    Fumio Ohta
    1940 Volume 39 Issue 1 Pages 26-36
    Published: September 30, 1940
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Yakriton exerts, as has been published in Part 11) of the present paper, an accelerating effect upon the rate of urinary elimination of phenolsulphonphthalein injected intravenously.
    1. Now when yakriton was used 30 minutes prior to dye injection, it was not so effective in the amount of 1/4 R. A. U. or 2 R. A. U. (per kilo of body weight) as in the amount of 1 R. A. U. (per kilo) (Cf. Tables 1, 2, 3 and 5).
    2. When yakriton was used 30 minutes prior to dye injection, it was not so effective in the amount of 1 R. A. U. (per kilo of body weight) as in the amount of 1/2 R. A. U. (per kilo) (Cf. Tables 2 and 5, of the preceding paper, 1) and Tables 2 and 5 of this paper).
    3. When yakriton was injected in the amount of 1/2 R. A. U. per kilo of body weight for 4 consecutive days, and dye was injected 30 minutes after the last injection of it, the rate of the dye elimination was not accelerated (Cf. Tables 4 and 5).
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  • 98th Report Contribution to the Usage of Yakriton against Experimental Chromate Nephritis
    Fumio Ohta
    1940 Volume 39 Issue 1 Pages 37-46
    Published: September 30, 1940
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    I investigated the therapeutic effect of yakriton on experimental chromate nephritis from urine protein content, and examined, besides, the functional kidney test by means of phenolsulphonphthalein. I ob-tained the following results:-
    1. Experiment 1. In this experiment 0.5% aqueous solution of potassium chromate was injected in the amount of 0.5 c. c. per kilo of body weight. Control animals were put to urine examination and kidney. function test on the 4th day of the poison injection. And the yakriton animals were injected with yakriton in the amount of 1/4 R. A. U. per kilo of body weight (once a day) 4 times after the poison injection and put to the same tests, as has been shown in Fig. 1. Urine protein content of the control animals was somewhat larger than that of the yakriton animals (Cf. Tables 1 A and B). The total amount of the dye excreted through the kidneys in the 1st 4 hour portion was smaller by 10.8% in the control animals, and larger by 2.7% in the yakriton animals, than the normal (Cf. Table 4).
    2. Experiment 2. This experiment differed from Exp. 1 only in the amount of poison used. In this experiment it was used in 1 c. c. per kilo of body weight instead of 0.5 c. c.. Urine protein content of the control animals was larger than that of the yakriton animals (Cf. Tables 2 A and B). The total amount of the dye excreted in the urine in the 1st 4 hour portion was smaller by 42.5% in the control animals, and by 2.6% in the yakriton animals, than in the normal (Cf. Table 4).
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  • Tomezô Huziwara
    1940 Volume 39 Issue 1 Pages 47-65
    Published: September 30, 1940
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
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  • Koiti Motokawa
    1940 Volume 39 Issue 1 Pages 66-83
    Published: September 30, 1940
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    Wird ein Froschhautpräparat, das, gut fixiert mit Sieben, an einem Osmometer angebracht ist, mit kurzem Induktionsstrom gereizt, so tritt eine Flüssigkeitsbewegung mit einer Latenz von einigen Zehn-tel Sekunden auf.
    1. Es lassen sich zwei Komponenten an dieser Erscheinung unterscheiden, von denen eine gegen den auf die Haut angelegten hydro-statischen Überdruck auftritt, während die andere immer in der Rich-tung der Sekretion gerichtet ist.
    2. Die beiden Komponenten verkleinern sich mit der Abnahme der hydrostatischen Druckdifferenz.
    3. Diese Flüssigkeitsbewegung geht unter Einwirkung von KCN und verschiedener Narkotika reversibel verloren.
    4. Sie wind durch Atropin gehemmt, dagegen durch Acetylcholin befördert.
    Es wurde aus all dem erwähnten geschlossen, dass diese neue Erscheinung nichts anderes als ein Ausdruck der sekretomotorischen Funktion der Hautdrüsen ist, und der Mechanismus der Sekretion wurde weiter erörtert.
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  • 135th Report of the Peroxidase Reaction
    Shizuo Kimura
    1940 Volume 39 Issue 1 Pages 84-102
    Published: September 30, 1940
    Released on J-STAGE: November 28, 2008
    JOURNAL FREE ACCESS
    In the present paper I have examined the platelet count of ap-parently “healthy” lactating mothers with very different Arakawa's reaction on different sides of the breast. Such cases are rare, of course. And the cases I selected were those with the index over 8 (Cf. p. 85) -or with very different reaction on different sides of the breast.
    All my own 30 cases were divided into 3 groups (Groups A, B and C) according to the intensity of Arakawa's reaction of the stronger side breast. In each group, the average count showed re-spectively an increase as compared with the average count of mothers with the reaction of the stronger side on both breasts.
    The platelet count given by J. Kimura, 2)3) the reticulocyte count by Shiraishi9-11), the milk chlorine content by Ishii, 12) the milk sul-phate content by Yoshino13) and the milk sodium content by Kuro-sawa15) in such cases-mothers with very different Arakawa's reac-tion on different sides-shwoed an increase or a high figure in each report. On the other hand the milk glyoxalase content by Orimo17) in such cases showed a decrease (Cf. Table 12). An increase of the blood platelet count, reticulocyte count, milk chlorine content, milk sulphate content and milk sodium content, and at the same time a de-crease of the milk glyoxalase content respectively were, as they re-port, seen in lactating mothers with negative Arakawa's reaction. Thus, it is probable that such mothers are in a state of avitaminosis B, however strong may be the Arakawa reaction on one side of the breast.
    It is to be added here that it is a question whether or not a lac-tating mother who secretes on one breast alone and whose Arakawa's reaction is normally positive is always healthy, especially if the reac-tion is tested only once.
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