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Volume 52 (1950)
- Issue 3-4 Pages 207-
- Issue 1-2 Pages 1-
Volume 52, Issue 1-2
Displaying 1-37 of 37 articles from this issue
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Kiichiro Suzuki1950 Volume 52 Issue 1-2 Pages 1-7
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSBy making use of the method of electric flicker, I measured throughout 24 hours the degree of fatigue and recovery of Japanese railroad men in all kinds of labor (ordinary, a little severe and very severe labor).
The degree of fatigue caused by ordinary labor amounted to about 200 mV when they were leaving office, the maximum value for a little severe labor was about 300 mV at the end of work, and that for very severe labor rose above 400 mV. The value of fatigue measured by Motokawa's method of electric flicker run nearly parallel with the quantity of work done, and corresponded well to the felling of fatigue in many cases.
The author has pleasure in acknowledging his indebtedness to Prof. K. MOTOKAWA who has guided him kindly.View full abstractDownload PDF (351K) -
(5th Report) “Secondary Screening” Test on 15 Strains of Actinomyces, Specifically Antagonistic to Acid-fast BacteriaMasahiko Kuroya, Nakao Ishida, Ken Katagiri, Takehiko Shiratori, Reiko ...1950 Volume 52 Issue 1-2 Pages 8
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Kiichiro Suzuki1950 Volume 52 Issue 1-2 Pages 9-16
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn exercise by a bicycle ergometer, running and exercise of going up and down stairs, I compared the oxygen consumption with the degree of fatigue as measured by the method of electric flicker and obtained the following results.
Data of the electrical measurements went nearly parallel with oxygen consumption during the exercises, while during the time of recovery some discrepancy was found. between both sorts of measurements; the recovery was attained always earlier as to oxygen consumption than as to the electrical values.
The time course of recovery showed sometimes especially after severe exercise a negative phase which could be proved more clearly by the electrical method than by the measurement of oxygen consumption.
The author has pleasure in acknowledging his indebtedness to Prof. K. MOTOKAWA who has guided him kindly. He also acknowledges with gratitude the support given to him by Prof. K. MATSUDA.View full abstractDownload PDF (432K) -
First Report. A Search for the Group (A, B, O)-Specific Substance in the Lipoid FragmentYutaka Hamasato1950 Volume 52 Issue 1-2 Pages 17-27
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Strong group-specific lipoid-fractions were obtained from red blood cells.
2. From the physical and chemical properties of those fractions and for reasons by analogy the writer considered: a) the group lipoids from the present source contain galactose, sphingosine, nitrogen and phosphorus in the equivalent proportions of 1:1:3:2 in common, and the content of the sugar is nearly 16%; b) these active factors possess a solubility atypical of lipoids, namely, they give a complete solution in hot water and are difficultly soluble in such usual organic solvents as alcohol, ether, petroleum ether and acetone.
3. A “co-adsorbent” is present in erythrocytes. It resembles the group specific lipoids in composition (only qualitatively examined) as well as in solubility and promotes the sero-reaction of these.View full abstractDownload PDF (661K) -
(6th Report) On the Properties of Several Kinds of Streptothricin-like SubstancesMasahiko Kuroya, Nakao Ishida, Ken Katagiri, Jiro Konno, Masami Kikuch ...1950 Volume 52 Issue 1-2 Pages 28
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Second Report. Is any Group Polysaccharide Existent in Erythrocytes?Yutaka Hamasato1950 Volume 52 Issue 1-2 Pages 29-33
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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8th Report: Naevus fusco-caeruleus ophthalmomaxillaris OTA. Preliminary ReportKunio Yoshida1950 Volume 52 Issue 1-2 Pages 34
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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The Blood Group Substance in Red Blood Cells. Third Report. Is any Group Protein Present in Erythrocytes?Yutaka Hamasato1950 Volume 52 Issue 1-2 Pages 35-38
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Hachiro Seto, Shigeaki Yamamoto, Tsutanosuke Fujii1950 Volume 52 Issue 1-2 Pages 39-42
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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The Sixth Report. Function of Blood DiastaseSyoiti Yamagata1950 Volume 52 Issue 1-2 Pages 43-47
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSFrom these experiments the following conclusion can be brought out: The blood diastase is usefull for the carbohydrate metabolism, assisting in the hydrolysis of glycogen which is poured out into the plasma from the liver cells as such.View full abstractDownload PDF (262K) -
Preliminary ReportMasao Abe1950 Volume 52 Issue 1-2 Pages 48
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Masabumi Yamasaki1950 Volume 52 Issue 1-2 Pages 49-52
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Kituya Iwama1950 Volume 52 Issue 1-2 Pages 53-62
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA delayed conditioned reflex was established in man with a metronome as a conditioned stimulul and with an electric light as an unconditioned one. The interval between the beginning of the metronome and the administration of the electric light was twenty seconds. Changes in electroencephalograms were studied in the course of the establishment of the conditioned reflex.
1. As the conditioning proceeded, cortical responses to the com-bination of the conditioned and unconditioned stimulus changed in a characteristic manner.
2. When the delayed conditioned reflex was completely established, the amplitude of α-waves increased at the onset of the metronome. In spite of the absence of the unconditioned stimulus the so augumented α-waves were suppressed and β-waves appeared at about the 20th second from the start of the metronome beats. The augumentation of the α-waves is an expression of the internal inhibition developed during the de-layed conditioned reflex, and the suppression of the α-waves and the ap-pearance of the β-waves represent the conditioned cortical excitation.
3. An extra-stimulus inhibited the effect of the inhibition induced by the conditioned stimulus and elicited a long lasting train of β-waves (disinhibition).
4. Experiments on generalisation, differentiation and experimental extinction were carried out when the conditioning was complete. After the differentiation or extinction had been established, it was found that a-waves were well developed in the whole extent of the oscillogram. This phenomenon must be attributed to the differential or extinctive inhibition.
5. The nervous mechanism underlying excitation and inhibition was discussed on the basis of experimental evidence.View full abstractDownload PDF (685K) -
Kituya Iwama1950 Volume 52 Issue 1-2 Pages 63-68
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSElectroencephalograms (eeg) were recorded in normal subjects, who breathed gas mixtures containing from six to eleven volume per cent oxygen for five to seven minutes. Changes of eeg were expressed with mean am-plitude and mean period obtained from the recorded brain waves.
1. Under a high degree of oxygen lack, following changes of eeg were observed. Within a minute after the beginning of the gas breathing, small rapid waves appeared, and corresponding to this change, the mean period was temporarily diminished. Two or three minutes later slow large δ-waves appeared in groups, and the mean amplitude and mean period increased rapidly hand in hand. In the final stage of the gas breathing eeg consisted of almost only δ-waves.
2. In oxygen lack of a slighter degree potentials were markedly sup-pressed at an early stage of the gas breathing, and thereafter the mean period increased prior to the mean amplitude.
3. Soon after the cessation of the gas breathing, δ-waves disappeared, but the normal pattern of eeg was not recovered for a long time. Eeg at the recovery stage were found similar to those obtained in mental fatigue.View full abstractDownload PDF (399K) -
Umon Fukuyama, Kengoro Matsumoto1950 Volume 52 Issue 1-2 Pages 69-75
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Kojiro Matsuda1950 Volume 52 Issue 1-2 Pages 75-76
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Chigashi Suzuki1950 Volume 52 Issue 1-2 Pages 77-86
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Shigeji Kondo1950 Volume 52 Issue 1-2 Pages 87-94
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe fact that a substance which resembled very closely penicillin could be obtained from the culture filtrate of a strain of penicillia isolated by the author was revealed by the present paper. Thus it was shown that there was considerable evidence of biological similarity between penicillin and the isolated antibiotic substance.
1) A strain of penicillia which produced in cultures a powerful anti-bacterial substance against Gram-positive bacteria was isolated from a contaminating blood plate in the laboratory.
2) The antibacterial power of the cultures reached its maximum in about 11 days at 20°-25°C. and after 12 days diminished, until it had almost disappeared in 27 days.
3) The best one of all culture media used for the production of the antibacterial substance was a Czapek medium with 1% Katayama's peptone (initial pH. was 7.0). In reference to the Czapek medium, kinds of peptones used had a great effect upon the potency of antibiotic sub-stances, but not upon the growth and the spore formation of this fungus.
4) The culture filtrate inhibited the growth, in particular, of sta-phylococci, streptococci, Bac. anthracis, Corynebact. diphtheriae, gonococci, meningococci, and pneumococci, namely Gram-positive bacteria, but not the growth of B. coli, Salmonella typhi, S. paratyphi A, S. paratyphi B, S. enteritidis B. dysenteriae, Proteus vulgaris, P. pyocyanea, or Vibrio cholerae, namely Gram-negative bacteria.
5) The rate of killing of staphylococci by the culture filtrate was very weak. It was thought, therefore, that its action was bacteriostatic rather than bactericidal.
6) The antibacterial titre of small bright yellow drops which were collected on the surface of the fungus was higher than the titre of the culture filtrate.
7) Passage through the Berkefeld filter diminished the antibacterial power, but not through the Seitz filter or filter paper.
8) At pH 2.0 the culture filtrate lost almost all powers after 1 day at the refrigerator temperature, but if its reaction was kept from pH 5.0 to 7.0, it could be preserved almost constantly after 14 days.
9) The active agent of the culture filtrate was thermostable, if it was kept from pH 5.0 to pH 7.0, but boiling at pH 2.0 for 30-60 minutes re-duced the power considerably.
10) The culture filtrate was able to be concentrated to one fifteenth of its volume by means of vacuum distillation at about 35°C. without di-minishing of the antibiotic titre.
11) The culture filtrate was non-toxic to animals in enormous doses.
12) The active constituent could be extracted as a calcium or sodium salt from the culture filtrate.View full abstractDownload PDF (462K) -
VI. The Genesis of the Nevus CellMinor Ito1950 Volume 52 Issue 1-2 Pages 95-101
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. By means of the Bielschowsky-Seto's method of neurofibril stain-ing, the author have concluded that the nevus cell is not the production of the “Abtropfung” of epidermis (Unna), but originates from the neuro-ectodermal cell which is homogenetic with the Schwann's cell of Masson.
2. I have recognized the argentaffinity of the Schwann's cell by Bielschowsky-Maresch's staining, and have supported the neurogenic nature of nevus cell. But I am obliged to regect the so-called Abtropfung theory on account of the indifferent attitude of argentaffin fibril against the epi-dermis.
3. The author believes the melanin production depends entirely upon the chemical reaction in the cell which is in contact with the termination of peripheral vegetable nerve, and that it does not matter whether the cell is ectodermal or mesodermal.View full abstractDownload PDF (1784K) -
Taizo Suzuki1950 Volume 52 Issue 1-2 Pages 102
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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CXXV. Glycidamins in Human BileHirosi Tiba1950 Volume 52 Issue 1-2 Pages 103-110
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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CXXVI. Structural Study of A-specific Carbohydrate from Mucus Mucin of Pig Stomach. Second PaperZensaku Yosizawa1950 Volume 52 Issue 1-2 Pages 111-117
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1) The unit disaccharide (N-acetylglucosamine-galactoside) of the A group carbohydrate (separated from mucus-mucin of pig stomach) re-duces 3 mols of periodic acid per mol.
2) It is cleft by β-galactosidase from snail liver.
3) From these findings it is assumed that, in this compound, galactose links position 4 of acetylglucosamine through β-glucosidic union, if glucos-amine takes the pyranose form.
4) N-acetylglucosamine, α-methyl-N-acetylglucosaminide and lac-tose reduce 3, 1 and 4 mols of periodic acid respectively per mol.View full abstractDownload PDF (254K) -
Preliminary Report: “On Angioreticulin”Takeshi Kurobane1950 Volume 52 Issue 1-2 Pages 118
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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VII. Mongolian Spot Cell and Blue Nevus CellMinor Ito1950 Volume 52 Issue 1-2 Pages 119-124
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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VIII. Melanodermatitis facieiSusumu Iijima1950 Volume 52 Issue 1-2 Pages 125-134
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Kenji Honda, Takeo Otomo1950 Volume 52 Issue 1-2 Pages 135-137
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Preliminary ReportShinji Takahashi1950 Volume 52 Issue 1-2 Pages 138
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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62nd Hematological PaperKakujiro Sakai, Shinji Takahashi, Tsuneyoshi Yano, Hozo Kakazu, Kiyohi ...1950 Volume 52 Issue 1-2 Pages 139-143
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Preliminary ReportShinji Takahashi, Takehiko Nikaido1950 Volume 52 Issue 1-2 Pages 144
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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CXXVII. Structural Study of A-specific Carbohydrate from Mucus Mucin of Pig Stomach. Third PaperZensaku Yosizawa1950 Volume 52 Issue 1-2 Pages 145-150
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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CXXVIII. Structural Study of A-specific Carbohydrated from Mucus Mucin of Pig Stomach. Fourth PaperZensaku Yosizawa1950 Volume 52 Issue 1-2 Pages 151-155
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Preliminary ReportTakeshi Hoshi1950 Volume 52 Issue 1-2 Pages 156
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Sokichi Furuhashi1950 Volume 52 Issue 1-2 Pages 157-164
Published: 1950
Released on J-STAGE: November 17, 2010
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1st Report. On the Toxemias of Late Pregnancy Excluding EclampsiaHideo Nagase1950 Volume 52 Issue 1-2 Pages 165-172
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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2nd Report. Clinical Study of Eclampsia and its Recurrence and Transition to Chronic TypeHideo Nagase1950 Volume 52 Issue 1-2 Pages 173-180
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
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Shungo Osato1950 Volume 52 Issue 1-2 Pages 181-194
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn this paper I have reported four cases of stomach cancer, who had been cured with chemotherapy and on reexamination after 6 months to 4 years were found free from relapse. Some other cases, in whom chemo-therapy was efficacious, are given briefly. Two cancer cases, who were treated with chemotherapy under cooperation of surgery, are mentioned.View full abstractDownload PDF (6211K) -
Koiti Motokawa, Kiitiro Suzuki1950 Volume 52 Issue 1-2 Pages 195-206
Published: May 31, 1950
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe time course of changes in electrical excitability of the eye after 2 seconds' illumination by white light was investigated in normal and color-blind subjects.
1. The excitability curve obtained by plotting ζ-values or percentage increases in electrical excitability as ordinates against the time after the end of illumination as abscissae showed a single maximum at 2 seconds in normal subjects. In the deuteranope, two distinct elevations were found on the excitability curve, while the curve taken from the protanope showed a single maximum At one second.
2. The excitability curve for white light obtained from deuterano-malous subjects showed distinct three elevations which were termed R, G and Bin the order of rapidity of development. It was shown that the three elevations represent three independent processes but not different phases of one and the same process. The development of the G process is weak in the deuteranomalous and entirely lacking in the deuteranope, so that there appear only two elevations in the excitability curve of the deuteranope.
3. The G elevation of the excitability curve taken from deuteranomal-ous subjects disappeared at a sufficiently low intensity of illumination, so that the excitability curve taken under such conditions could not be dis-tinguished from that of the deuteranope.
4. The wave-lexxgth dependence or spectral locus of each color pro-cess was investigated. The locus of the B process has its maximum at about 460mμ in all cases of normal and color-blinds. The R locus could not be found in the protanope, and the G locus was found lacking in the deut-eranope. The R and G loci obtained from the color-blinds had a maximum at 610 mμ and 530 mμ respectively. The locations of these maxima did not coincide precisely with those of the corresponding loci taken from the fovea of normal man, but showed a close agreement with those of the cor-responding loci taken from a parafoveal region of the retina of normal man.
In the deuteranomalous, the B and R loci showed normal behavior in all respects, but the G locus was found always smaller than normal not only in the maximum height but also in the extent of the locus over the spectrum. In one case of the deuteranomalous, the G process extended over such a narrow range of the spectrum as between 490mμ and 570mμ. It is worthy of note that the defect in color vision was so severe in this case that it could not be distinguished from a true deuteranope by tho routine anomaloscopic test and by our method of excitability curves for white light.View full abstractDownload PDF (740K)
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