All issues
Volume 112 (1974)
- Issue 4 Pages 293-
- Issue 3 Pages 197-
- Issue 2 Pages 103-
- Issue 1 Pages 1-
Volume 112, Issue 4
Displaying 1-12 of 12 articles from this issue
- |<
- <
- 1
- >
- >|
-
SHOZO NAKAMURA, YOSHIAKI TAKEZAWA, KO SASAKI, GEN YOSHIDA, TAKASHI SAT ...1974 Volume 112 Issue 4 Pages 293-297
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA new method is devised to show characteristic changes of hepatic sinusoids in hepatic cirrhosis. After a venous catheter was wedged into the hepatic veins and the wedged hepatic venous pressure was recorded, a contrast medium was slowly infused by gravity at a pressure which was slightly higher than the wedged hepatic venous pressure and was sufficient to flow slowly into the hepatic veins. By this method scattered nodules were shown in 74 per cent of the patients with hepatic cirrhosis, while uniform fine granular or reticular opacification of the sinusoids was observed in patients without hepatic diseases and in patients with hepatic diseases other than cirrhosis. Hepatic sinusoidography by this method is useful for the diagnosis of hepatic cirrhosis.View full abstractDownload PDF (2399K) -
AKIRA B. MIURA, AKIRA SHIBATA, TETSUO AKIHAMA, YASUYUKI ENDO, YASUKO S ...1974 Volume 112 Issue 4 Pages 299-313
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSUltrastructure of the erythroblasts in the bone marrow of human adults was studied. Although the knowledge of the stem cells has been increasing, the precise morphology of them is not yet clearly identified in the bone marrow specimen. However, the so-called proerythroblasts and the developing erythroblasts are easily identified under electron microscopic observations by the characteristic features such as the round shape of the cells, almost perfectly round nucleus with unique chromatin figures, polysome formation of a few ribosomes, a number of microtubules and micropinocytic vesicles, and siderosomes.View full abstractDownload PDF (5633K) -
TAKUJI OKITSU1974 Volume 112 Issue 4 Pages 315-323
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe effect of the intensity modulated tones on the electroencephalogram was investigated in normal and hearing-impaired subjects. In all normal subjects and most cases of the conductive hearing loss, the response was not evoked by the increment by 4 dB from the basic tone at 20 dB above the subjective threshold. The size of the minimal increment which effectively evoked the response was generally smaller in the cochlear hearing loss than in the normal and the conductive hearing loss. A particular case of cochlear disorder showed the response even when the increment of 0.6 dB was tested. The results suggest that this method is useful for differentiating lesions in the auditory system objectively.View full abstractDownload PDF (336K) -
MASARU OIRAWA, ERIC N. C. MILNE1974 Volume 112 Issue 4 Pages 325-338
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSWe have used serial microangiography and radioactive 133Xe to study microvascular morphology and to quantify blood flow in Walker 256 carcinomas implanted in rat tails during growth and immune rejection. Two tumour groups were indentified. Group A grew rapidly with a 2 to 6 times increase in blood flow, and caused death in 10 days. Group B grew more slowly and increased blood flow 2 to 4 times. At 6 to 8 days after implantation the B tumours diminished in size, blood flow decreased and extensive lymphocytic infiltration developed. By 21 days all evidence of the tumour disappeared. The rejection appears to be cell-mediated and the high incidence of tumour rejection (65-70%) to be related to the number of tumour cells and/or presence of foreign cellular debris in the inoculum. Microangiographic changes during immune rejection were specific and included marked tortuosity of feeding vessels and a “ghost-like” fading out of tumour vessels quite unlike the appearance of necrosis.View full abstractDownload PDF (5169K) -
YOSHIO GOTO, SHIN-ICHIRO SATO, MITSUO MASUDA1974 Volume 112 Issue 4 Pages 339-353
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe cause of death and the patho-anatomical changes of various organs were analyzed in 3, 151 diabetic autopsy cases, which were collected from Annual Reports of Pathological Autopsy Cases (1958-1970) published by the Japanese Society of Pathology. In 2, 754 primary diabetics, the causes of death were as follow: diabetic coma 4.5%, arteriosclerotic cardiovascular diseases 41.2% (renal 19.3%, cerebral 11.1%, coronary 6.5%), infections 19.4% (tuberculosis 4.6%, lung 5.8%, urinary tract 3.3%, biliary tract 1.0%), malignant neoplasms 15.9% (stomach 3.9%, lung 3.7%), miscellaneous 15.2%. Diabetic coma was most common in the first decade and decreased with age. Infections were high in the third and fourth decades but showed no tendency to increase with age. Among the infections, the highest was purulent pulmonary disease. The arteriosclerotic cardiovascular disease was not seen in the first and the second decade as the main cause of death. They appeared at the third decade and increased with age. As compared with the reports from American and European countries, a high incidence of diabetic nephropathy and a low incidence of ischemic heart disease are characteristic of this series. As a cause of the low incidence of ischemie heart disease, the low consumption of fat in this country was proposed. Diabetic glomerulosclerosis was high in the third to sixth decades, especially in females. The incidence of cerebral infarction in this diabetic series was significantly higher than that in the general population, but that of cerebral hemorrhage was not different from that in the general population. 397 cases were classified as secondary diabetes (12.6%). These consisted of 96 pancreatic cancer, 25 pancreatitis, 175 liver cirrhosis, 22 hemochromatosis, 16 endocrine diseases and 63 steroid diabetes.View full abstractDownload PDF (729K) -
TADASHI IGARI, YOSHINORI TOBA, KIJURO OBARA, SHIGERU ONO1974 Volume 112 Issue 4 Pages 355-359
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSTryptophan metabolites through 5-hydroxytryptamine in the synovial fluid and blood of patients with rheumatoid arthritis and those with osteoarthritis were investigated in order to know the role of serotonin in the joint diseases. A metabolic map of tryptophan in the synovial fluid was also made. There were no significant differences in the levels of 5-hydroxytryptamine and 5-hydroxyindole acetic acid in the synovial fluid between rheumatoid arthritis and osteoarthritis, but the activity of monoamine oxidase in the synovial fluid was higher in osteoarthritis than in rheumatoid arthritis.View full abstractDownload PDF (251K) -
TOSHIRO SAKURADA, SHINTARO SAITO, MAKIKO YAMAMOTO, TORU YAMAGUCHI, KAT ...1974 Volume 112 Issue 4 Pages 361-364
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSAdministration of prednisolone, 30mg per day, for a month followed by its alternate-day administration was very effective to restore the thyroid function and clinical symptoms in a rare case of hypothyroidism caused by chronic thyroiditis with inflammatory symptoms. Decreased serum T3 and T4 in this patient were increased to normal values by the administration of prednisolone and increased serum TSH became undetectable.View full abstractDownload PDF (925K) -
TOSHIRO SAKURADA, SHINTARO SAITO, TORU YAMAGUCHI, KATSUMI YOSHIDA, MAK ...1974 Volume 112 Issue 4 Pages 365-371
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn a case of hypothyroidism with clubbing of fingers and toes, exophthalmos, myxoedema tuberosum and myxoedema pretibiale, serum T4 value was low, but both values of serum T3 and TSH were normal and serum LATS was potitive. Three months later both values of serum T4 and T3 decreased and serum TSH value increased without any treatment. These results show that serum T3 as well as T4 might be related to the feedback control of TSH secretion. In a case of Pendred's syndrome, serum T4 value was low, values of serum T3 and BMR were within normal and serum TSH value was high. Normal serum T3 may have kept this patient in a state of compensatory hypothyroidism. In these patients, administration of 25-50 μg of l-T3 per day was sufficient to suppress the secretion of serum TSH from thyroid gland completely.View full abstractDownload PDF (1783K) -
TADAO ORII, TAKAMICHI CHIBA, RYOJI MINAMI, KAZUKO SUKEGAWA, TOORU NAKA ...1974 Volume 112 Issue 4 Pages 373-380
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSUrinary cetylpyridinium chloride (CPC)-precipitates and non-CPC-precipitates in normal male children and seven patients with a new type of mucolipidosis, GM1-gangliosidosis type 1, I-cell disease, Hurler syndrome, Morquio syndrome, Gaucher's disease adult type and Tay-Sachs disease were studied using several methods including Sephadex G-25 gel filtration, ECTEOLA-cellulose column chromatography and enzymatic digestion with chondroitinase ABC. 1) Considerable amounts of glycopeptide fractions were detected in the urine of the patients with a new type of mucolipidosis, Gm, -gangliosidosis type 1, I-cell disease and also Gaucher's disease adult type compared with that of normal male children and other patients. 2) The total acid mucopolysaccharides excreted into the urine from two patients with Hurler syndrome and Morquio syndrome were much higher than those excreted in normal male children and other patients. 3) Large amounts of the chondroitinase ABC-resistant acid mucopolysaccharides were found in the urine of patients with Hurler syndrome, Morquio syndrome and GM1-gangliosidosis type 1.View full abstractDownload PDF (1030K) -
KAZUHIKO IWATSUKI, SHOW TUBOI, KOROKU HASHIMOTO1974 Volume 112 Issue 4 Pages 381-382
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDopa decarboxylase was isolated from rat liver and the effects of active polypeptides and prostaglandins on dopa decarboxylase activity were investigated. Polypeptides and prostaglandins used were as follow: secretin, pancreozymin, glucagon, insulin, eledoisin, kallikrein, bradykinin, angiotensin II, gastrin, prostaglandin E1, E2 and F2α. Only kallikrein among these compounds inhibited the dopa decarboxylase activity at doses from 0.3 to 1.0 unit per 3 ml. According to the Lineweaver-Burk plot, this inhibition appeared to be non-competitive. It is suggested that kallikrein may exert some influence on the conversion of dopa to dopamine.View full abstractDownload PDF (109K) -
KEIZO MATSUMOTO, HISAO KIMURA, KIYO NISHIOKA, YUKIO NOGUCHI, YOSHIO UZ ...1974 Volume 112 Issue 4 Pages 383-384
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA new technique for determining causative agents in various sites of air way in patients with respiratory infection was devised in which sputum specimens were directly aspirated from various sites of air way by use of the Kifa-Green catheter and each of them was cultured for the determination of causative agents. This method has an advantage for obtaining information of an exact location of causative agents in air way. Main causative agents detected by this method in patients with various respiratory infection were Haemophilus influenzae, Pseudomonas aeruginosa, and Diplococcus pneumoniae.View full abstractDownload PDF (131K) -
TADAO ORII, MAMORU YAMAGUCHI, RYOJI MINAMI, TOORU NAKAO1974 Volume 112 Issue 4 Pages 385-387
Published: 1974
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe fresh plasma infusion in patients affected by Hurler, Scheie or Morquio syndromes was followed by a decreased urinary excretion of chondroitin sulfate B or keratosulfate. Furthermore, in all of the patients the infusion was followed by an increased excretion of the noncetylpyridinium chloride precipitates.View full abstractDownload PDF (149K)
- |<
- <
- 1
- >
- >|