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Volume 104 (1971)
- Issue 4 Pages 305-
- Issue 3 Pages 205-
- Issue 2 Pages 105-
- Issue 1 Pages 1-
Volume 104, Issue 2
Displaying 1-14 of 14 articles from this issue
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KENICHI IWATSUKI, YASUHIKO HASHIMOTO, TAKESHI SHIMA1971 Volume 104 Issue 2 Pages 105-109
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe effects of Trasylol® (Bayer) on the action of muscle relaxants and the serum cholinesterase activity were investigated in view of controversial opinions on the question. Studies were carried out in man anesthetized with nitrous oxide-oxygen and halothane. The results revealed that Trasylol in doses of 25, 000 to 30, 000 K. I. units, when given intravenously, exerted no effect on d-tubocurarine block, while the same dose of Trasylol produced a slight transitory potentiation of succinylcholine block. Trasylol in doses of 25, 000 to 50, 000 K. I. units did not affect the serum cholinesterase activity. From the results obtained an interaction between Trasylol and muscle relaxants seemed to be clinically insignificant.View full abstractDownload PDF (957K) -
KENICHI IWATSUKI, MASAHIRO SUZUKI, TSUNEO YUSA, YASUHIKO HASHIMOTO1971 Volume 104 Issue 2 Pages 111-120
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSPentazocine was used as an alternative for fentanyl in combination with droperidol in neuroleptanesthesia and the results were compared with those of the ordinary techniques using droperidol and fentanyl or Thalamonal®. This modified technique proved to have advantages such as smooth induction of anesthesia, cardiovascular stability during surgery, rapid recovery of consciousness and postoperative tranquility, which were comparable to those of the ordinary techniques. Pentazocine caused less respiratory depression than fentanyl. Moreover, this technique was convenient for clinical practice, because the analgesic drug used was not narcotic. The longer duration of action of pentazocine appeared to be disadvantageous for the controllability of anesthesia, but it was considered to outweight the drawback in view of postoperative pain relief. The data of experimental studies also supported the clinical results. Pentazocine seemed to be a suitable alternative for fentanyl as a component of neuroleptanesthesia.View full abstractDownload PDF (3269K) -
KOZO WATANUKI, KAZUTOMO KAWAMOTO, SHUICHI KATAGIRI1971 Volume 104 Issue 2 Pages 121-127
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe light microscopical structure of Reissner's membrane was studied in the cat. The epithelial cells facing the endolymphatic space are smaller on the inner (modiolus) side and they become larger towards the outer (spiral ligament) side of Reissner's membrane. The epithelial cells on the inner side of the membrane are more vulnerable to post-mortem changes. The mesothelial cells facing the perilymphatic space are very elongated and fusiform in shape with a regular arrangement from the inner to the outer side of Reissner's membrane. Post-mortem changes of the mesothelial cells consisted in separation of cell junctions or detachment from the basement membrane.View full abstractDownload PDF (4056K) -
NOBUAKI SASANO, YOSHIAKI TAKEZAWA, HIRONOBU SATO, NORIKO HORIKAWA1971 Volume 104 Issue 2 Pages 129-141
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSMicro-vascular patterns in the human adrenals in the course of development and in adults were visualized by postmortal angiography and examined in relation to adrenocortical lesions. The terminal unit of the arterial blood supply to the adult adrenal cortex consists of the capillary dome in the glomerulosa with brush-like capillaries perforating the fasciculata, while the zona reticularis receives arterial blood from the arteriae medullae. Therefore, the proper fasciculata is situated in the utmost periphery of the arterial circulation. The capillary dome as the terminal unit of the arterial blood supply plays an important role in precipitating various adrenocortical lesions. Capillary dysarrangement was rather indistinct in nodular hyperplasia, but it was remarkable in solitary intracortical nodules receiving several arterioles. In fetuses and newborns, cortical lesions appeared diffusely because they lacked capillary domes. The cortico-medullary vein drained from the glomerulosa into the medullary vein, while the emissary vein was demonstrated as large communications between the capsular and medullary veins. A circulatory blockade between the permanent and fetal cortex proceeding with fetal maturity was found responsible for neonatal hemorrhage involving exclusively the fetal cortex. The similarity of the adrenal vascular pattern of anencephalic newborns to that of normal infancy was ascribed to early involution of the fetal cortex in anencephalus.View full abstractDownload PDF (2980K) -
TOGO HORIUCHI, TADAAKI ABE, TAKESHI ISHITOYA, SHIGEO TANAKA, RYOSEI KU ...1971 Volume 104 Issue 2 Pages 143-149
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe corrected transposition of the great arteries with pulmonary stenosis was completely repaired in a 5 1/2-year-old boy. To relieve the stenosis of the pulmonary valve ring which was located posterior to the aorta and heart chambers, the valve-bearing tube-graft made of the pericardium was implanted as a bypass graft between the right-sided ventricle and the pulmonary trunk. Postoperative hemodynamics and cineangiographic findings were satisfactory. The use of the viable autologous tissue such as the pericardium is definitely more advantageous than that of the other homografts, since the former requires neither sterilization nor long-term preservation.View full abstractDownload PDF (3043K) -
MAKOTO ISHIZAKI1971 Volume 104 Issue 2 Pages 151-155
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSSkins of newborn F1 hybrids between C57BL/6 males and DBA/2 females were grafted to adult DBA/2 mice, including males, females and the hybrids' own mothers. Grafts of male F1-to-female DBA/2 were quickly destroyed, while those of other combinations survived slightly longer. The data suggest possibilities of donor-age effect to H-2 histoincompatibility in F1-to-parental allograftings and of postpartum unresponsiveness of mothers against both H-Y and H-2 antigens of their offspring.View full abstractDownload PDF (833K) -
KIYOSHI TAMURA, MASAO ENDOH, KOROKU HASHIMOTO1971 Volume 104 Issue 2 Pages 157-169
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSPharmacological features of the gall bladder and its vascular bed were studied by means of the intra-arterial administration of various substances in the dog in situ. The contraction of the gall bladder was produced by various compounds as follows: Cholinergic drugs, kinin substances, histamine, ganglion stimulants, ouabain, BaCl2 and CaCl2. Meanwhile, adrenergic drugs, ganglion blocking agents, lys-vasopressin, smooth muscle relaxants, KCl and MgCl2 relaxed the gall bladder. DMPP, 5-HT, nicotine, lobeline, angiotensin and ATP caused a biphasic response, i.e., a contraction followed by a relaxation or a relaxation followed by a contraction. The pharmacological features of cholecystic arteries are not the same as those of the gall bladder: Cholinergic and adrenergic drugs except isoprenaline, and ganglion stimulating and blocking agents produced opposite effects, while smooth muscle stimulants and relaxants acted similarly on both. Among polypeptides, lys-vasopressin relaxed the gall bladder, cholecystokinin constricted it, and gastrin and oxytocin caused no response, while the former constricted the artery and the latter three dilated it.View full abstractDownload PDF (689K) -
SHIGERU ONO, HIROKO HIRANO, KIJURO OBARA1971 Volume 104 Issue 2 Pages 171-175
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSDegradation of 17, 21-dihydroxy-20-ketone side-chain of cortisol by lens homo-genate was investigated and a fairly active degradation of adrenocortical steroid in the lens was verified. The assay system required the addition of nicotinamide adenine dinucleotide. Optimal pH, optimal temperature and the optimal medium composition for activity were also determined. The degradation product of corti-sol after loss of the side-chain was identified to be 11β-hydroxyandrost-4-ene-3, 17-dione by paper chromatography and scanning method using cortisol-4-14C as substrate.View full abstractDownload PDF (286K) -
OTOTAKA HIGASHI, YOSHIYUKI HONDA, MIWAKO KARITA, TSUNEO ARAKAWA1971 Volume 104 Issue 2 Pages 177-182
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe incidence in megakaryocytes with hypersegmentation of nuclear lobes was increased in the bone marrow of rats when fed on a diet deficient in folic acid with an addition of sulfaguanidine for a period of 2-3 weeks.View full abstractDownload PDF (868K) -
OTOTAKA HIGASHI, TSUNEO ARAKAWA, KUNIAKI NARISAWA, TOSHIO YOSHIDA, MIW ...1971 Volume 104 Issue 2 Pages 183-194
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSA7-year-old girl with low serum folate levels and macrocytic anemia, in which the bone marrow picture was predominated by the presence of megakaryocytes with a marked nuclear hypersegmentation, was described. The child had homocyst.inuria of vitamin B6 dependent type and had been under anticonvulsant therapy since her infancy. The nuclear shift of megakaryocytes was studied quantitatively and the results suggested that the hypersegmentation could be correctable by the administration of folic acid. A diagnostic significance of the nuclear hypersegmentation of megakaryocytes in folic acid deficiency was emphasized.View full abstractDownload PDF (1360K) -
TOSHIO YOSHIDA, KEIYA TADA, TSUNEO ARAKAWA1971 Volume 104 Issue 2 Pages 195-198
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSIn a patient with vitamin B6 dependent convulsions, the activity of glutamie acid decarboxylase (GAD) was found to be decreased when pyridoxal-phosphate (PALP) was not added in the reaction system for the enzyme assay. The activity was restored to normal level when PALP was added in large amounts in the reaction system. These findings suggest that the metabolic abnormality in this disorder exists in the binding abnormality between GAD apoenzyme and PALP.View full abstractDownload PDF (218K) -
AKIRA RIKIMARU, YASUE FUKUSHI, TAIZO SUZUKI1971 Volume 104 Issue 2 Pages 199-200
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSTransmural stimulation applied to the atropinized human taenia coli caused relaxation which was resistant to adrenergic neuron blocking agents. This relaxation was, however, entirely abolished by tetrodotoxin. These results may suggest the presence of non-adrenergic inhibitory nerves in the human taenia coli.View full abstractDownload PDF (114K) -
TOM MORI, HAJIME HOSHI1971 Volume 104 Issue 2 Pages 201-202
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSObservations on the spleen of chickens aging one day to 8 weeks showed that the development of the lymphoid tissue around Schweigger-Seidel ellipsoids proceeded quite independently of that of the thymus-dependent periarterial lymphoid tissue. These periellipsoidal lymphoid cells were considered to be bursadependent because of their depletion in bursaless chickens and their consistent increase irrespective of extirpation or destruction of the thymus.View full abstractDownload PDF (144K) -
OSAMU TAKEUCHI, SUSUMU SATOH, KOROKU HASHIMOTO1971 Volume 104 Issue 2 Pages 203-204
Published: 1971
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe infusion of the canine pancreas in situ was performed under constant pressure. It was found that dopamine caused a profuse flow of pancreatic juice with a slight vasoconstriction depending on the doses ranging from 1 to 10μg. The secretory response of dopamine was also obtained by intravenous administration. The authors suggest that dopamine acts a definite physiological role in the secretory mechanism of the pancreas.View full abstractDownload PDF (101K)
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