The close association of primary protein-losing gastroenteropathy with abnormalities of the lymphatic system has been well documented by the use of lymphangiography. However, although this method is effective in demonstrating the parietal lymphatic system, the abdominovisceral lymphatics are not seen.
As the cause of chronic atrophic gastritis, many factors have been suggested. However, experimental studies were few in this field and definite conclusion is not determined. On the other hand, it is well known that chronic gastritis is often observed in the residual stomach after gastrectomy. It is generally believed that the role of the regurgitation of duodenal content and the loss of gastrin stimuli are most important to cause postoperative gastritis.