A case of cancer complicating tuberculosis of the colon in a 39-year-old man is described. Barium enema showed strictures of coecum, transverse colon, descending colon, sigmoid colon and rectum. The lesion was diagnosed tuberculous on the findings of barium enema and biopsy from the rectal stricture. After the treatment with antituberculotic drugs for a year, passing disturbance of the coecum appeared. Right hemicolectomy was performed and papillary adenocarcinoma was found scattered in the hard scarring tissue of the coecum microscopically.