Seventy hundred and sixty one patients of cholelithiasis, who had been operated at twenty two hospitals in Aomori prefecture from 1964 to 1969, were investigated into the distribution of area, age, sex, occupation and so on. 1) Gallstones were classified into cholesterin stones, and pigmented calcium stones. Generally speaking, cholesterin stones and pigmented calcium stones were found in equal ratio in Aomori prefecture. In western part of the prefecture faced the Japan Sea, pigmented calcium stones got an advantage over cholesterin stones, but in some cities of the eastern part of the prefecture, cholesterin stones were predominant. In other districts, both stones were found in nearly equal ratio. 2) On the basis of vital statistics classified in age, 60 to 69 years old were the most frequent age to have gallstones. Pigmented calcium stones were less common than cholesterin stones among patients of age between 10 to 49 years old. Among older patients, pigmented calcium stones were almost equally frequent as cholesterin stones. 3) Women had much tendencies to have gallstones especially cholesterin stones. Pigmented calcium stones were equally distributed in men and women. 4) Divided the patients with cholelithiasis into professional and laboring groups, the laboring group existed in between 30 to 80 per cent of the patients, which were nearly equal to the ratio of inhabitants in these area. We should confirm that one of the reason why cholestrin stones were increasing at some cities in the prefecture recently might be the result of the increase of the number of professional group. Whereas, decreasing of pigmented calcium stones in other area might be the result of the decrease of the number of laboring group in the area.
Clinical and histopathological studies were made on 39 cases of erosive gastritis among the 227 cases of resected stomach specimen of benign ulcer. The results are as follows: 1) Erosive gastritis accompaning ulcer was observed in 17.2%. Highest incidence was observed in gastroduodenal ulcer, followed by duodenal ulcer, gastric ulcer respectively. 2) Erosive gastritis was more common in the male and most of the cases were the patients. between the age of 20 to 60. 3) Commonest complaint of the patient with erosive gastritis was abdominal pain. Bleeding was approximately 10%. Duration of complaint was about 6 months in average. 4) Examining occult blood, the positive rate was greater in the erosive gastritis with ulcer in comparison to the control. 5) Most of the cases of erosive gastritis showed hyperacidity of gastric juice. 6) Macroscopical observation revealed that most of the cases were diffuse protruded verioliform type and no cases of mixed type (protruded and excavated) were present. An exceptional case demonstrated diffuse protruded lesion on all over the mucosal surface from cardia to pylorus. Sometimes it is difficult to differentiate erosive gastritis from early stomach cancer and careful caution is necessary to establish the diagnosis. 7) Histologically, atrophy of pyloric gland and intestinal metaplasia is less common in erosive gasgritis. Lymphfollicular hyperplasia was observed in some degree. 8) It can be considered that erosive gastritis may appear during the course of mucosal atrophy. Repeated changes between erosion and regeneration may finally produce high grade of mucosal atrophy.