The activity of the Atopic Dermatitis Treatment Problem Committee of the JDA was reported. Last year, a cancer risk of tacrolimus ointment was proposed by the NPO organization and was reported in the newspapers. The Ministry of Health and Labor regired the doctors who prescribe this ointment, to provide informed consent of cancer risk. To help in the better understanding of this risk and to support the doctors to explain it to the patients, JDA published their opinion on this problem through the internets and other routs. Based upon more proper usage of tacrolimus ointmant both for adults and childran, the treatment guidlines were changed in 2003 and 2004. Some other problems related to adequate treatment of this disease were also reported.